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Taxonomic review of genus Microrhagus Dejean, 1833 from Korea, with description of a new species (Coleoptera, Eucnemidae, Melasinae, Dirhagini)

characters are also provided. eol>Eucnemidae; Korea; Microrhagus; new species; taxonomy - Copyright Jinbae Seung, Seunghwan Lee. This is an open access article distributed under the terms of the Creative

Taxonomic review of the genus Dirrhagofarsus in Korea (Coleoptera, Eucnemidae)

The genus Dirrhagofarsus is firstly recorded from Korea with three species: Dirrhagofarsus lewisi (Fleutiaux, 1900), Dirrhagofarsus modestus (Fleutiaux, 1923), and Dirrhagofarsus unicolor (Hisamatsu, 1960). A key to Korean species of Dirrhagofarsus, with diagnoses, redescriptions, and photographs of important structures is provided. In this work, Dirrhagus modestus f. unicolor...

Renal Ischemia-Reperfusion Injury in a Diabetic Monkey Model and Therapeutic Testing of Human Bone Marrow-Derived Mesenchymal Stem Cells

Clinically, acute kidney injury (AKI) episodes in diabetes mellitus (DM) patients are associated with a cumulative risk of developing end-stage renal disease. In this study, we asked whether the severity of AKI induced by renal ischemia-reperfusion injury (IRI) is more prominent in DM than in non-DM control using a cynomolgus monkey (Macaca fascicularis) model. We also...

Pharmacokinetic characteristics of telaprevir in healthy Korean male subjects and comparisons with Japanese

Pharmacokinetic characteristics of telaprevir in healthy Korean male subjects and comparisons with Japanese Yewon Choi,1 Seonghae Yoon,1 Kyoko Matsumoto,2 Yoshiyasu Ohta,3 SeungHwan Lee,1 Kyung-Sang

Pharmacokinetics and tolerability of eletriptan hydrobromide in healthy Korean subjects

Pharmacokinetics and tolerability of eletriptan hydrobromide in healthy Korean subjects Yu Kyong Kim,1 Kwang-Hee Shin,2 Jeffrey Alderman,3 Kyung-Sang Yu,1 In-Jin Jang,1 SeungHwan Lee1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea; 2College of Pharmacy, Kyungpook National University...

Evaluation of the effects of food on levodropropizine controlled-release tablet and its pharmacokinetic profile in comparison to that of immediate-release tablet

,* Jaeseong Oh,1 SeungHwan Lee,1 Sang-Min Cho,3 Youn-Woong Choi,3 Joo-Youn Cho,1 Beom-Jin Lee,2,4,* Jang Hee Hong5,* 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of

Comparison of tadalafil pharmacokinetics after administration of a new orodispersible film versus a film-coated tablet

,3 Min-Gul Kim,4 Eun-Heui Jin,5 JaeWoo Kim,5 SeungHwan Lee,1 Jang Hee Hong5,6 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul

Cryptic diversity of the subfamily Calaphidinae (Hemiptera: Aphididae) revealed by comprehensive DNA barcoding

Aphids are a species rich group comprising many important pests. However, species identification can be very difficult for aphids due to their morphological ambiguity. DNA barcoding has been widely adopted for rapid and reliable species identification as well as cryptic species detection. In this study, we investigated cryptic diversity in the subfamily Calaphidinae (Hemiptera...

Fully printable, strain-engineered electronic wrap for customizable soft electronics

ScholarSearch for Seunghwan Lee in:Nature Research journals • PubMed • Google ScholarSearch for Yongtaek Hong in:Nature Research journals • PubMed • Google Scholar Contributions J.B., B.L. and Y.H. conceived the ... , Inter-University Semiconductor Research Center (ISRC), Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 151-744, KoreaJunghwan Byun, Byeongmoon Lee, Eunho Oh, Hyunjong Kim, Sangwoo Kim, Seunghwan

The novel carboxylesterase 1 variant c.662A>G may decrease the bioactivation of oseltamivir in humans

Background Human carboxylesterase 1 (CES1) is a serine esterase that hydrolyses various exogenous and endogenous compounds including oseltamivir, a prodrug used to treat influenza. A novel CES1 c.662A>G single nucleotide polymorphism (SNP) was predicted to decrease CES1 enzymatic activity in an in silico analysis. This study evaluated the effect of the c.662A>G SNP on the...

A first-in-human, double-blind, placebo-controlled, randomized, dose escalation study of DWP05195, a novel TRPV1 antagonist, in healthy volunteers

Kim,3 Ji Duck Kim,4 Joo-Youn Cho,1 SeungHwan Lee,1 Namyi Gu5 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, 2Department of Clinical

Pharmacokinetics and tolerability of DA-8031, a novel selective serotonin reuptake inhibitor for premature ejaculation in healthy male subjects

Pharmacokinetics and tolerability of DA-8031, a novel selective serotonin reuptake inhibitor for premature ejaculation in healthy male subjects Dongseong Shin,1 SeungHwan Lee,2 Sojeong Yi,2 Seo Hyun

Revisit to three-dimensional percolation theory: Accurate analysis for highly stretchable conductive composite materials

Seunghwan Lee Yongtaek Hong OPEN A percolation theory based on variation of conductive filler fraction has been widely used to explain the behavior of conductive composite materials under both small and

Reassessment of Species Diversity of the Subfamily Denticollinae (Coleoptera: Elateridae) through DNA Barcoding

The subfamily Denticollinae is a taxonomically diverse group in the family Elateridae. Denticollinae includes many morphologically similar species and crop pests, as well as many undescribed species at each local fauna. To construct a rapid and reliable identification system for this subfamily, the effectiveness of molecular species identification was assessed based on 421...

Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers

Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers Kyungho Jang,1,2,* Min-Kyoung Kim,3,4,* Jaeseong Oh,1 SeungHwan Lee,1 Joo-Youn

Mitochondrial and bioenergetic dysfunction in trauma-induced painful peripheral neuropathy

Background Mitochondrial dysfunction is observed in various neuropathic pain phenotypes, such as chemotherapy induced neuropathy, diabetic neuropathy, HIV-associated neuropathy, and in Charcot-Marie-Tooth neuropathy. To investigate whether mitochondrial dysfunction is present in trauma-induced painful mononeuropathy, a time-course of mitochondrial function and bioenergetics was...

Pharmacokinetics of the evogliptin/metformin extended-release (5/1,000 mg) fixed-dose combination formulation compared to the corresponding loose combination, and food effect in healthy subjects

-jin Rhee,1,* SeungHwan Lee,1,2,* Seo Hyun Yoon,1 Joo-Youn Cho,1 In-Jin Jang,1 Kyung-Sang Yu1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and

Pharmacokinetic and pharmacodynamic interactions between metformin and a novel dipeptidyl peptidase-4 inhibitor, evogliptin, in healthy subjects

Pharmacokinetic and pharmacodynamic interactions between metformin and a novel dipeptidyl peptidase-4 inhibitor, evogliptin, in healthy subjects Su-jin Rhee,1,* YoonJung Choi,1,* SeungHwan Lee,1,2

Macroevolutionary Patterns in the Aphidini Aphids (Hemiptera: Aphididae): Diversification, Host Association, and Biogeographic Origins

Background Due to its biogeographic origins and rapid diversification, understanding the tribe Aphidini is key to understanding aphid evolution. Major questions about aphid evolution include origins of host alternation as well as age and patterns of diversification in relation to host plants. To address these questions, we reconstructed the phylogeny of the Aphidini which...