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Quantification of the type 2 diabetes risk in women with gestational diabetes: a systematic review and meta-analysis of 95,750 women

Aims/hypothesisWomen with gestational diabetes mellitus (GDM) are at risk of developing type 2 diabetes, but individualised risk estimates are unknown. We conducted a meta-analysis to quantify the risk of progression to type 2 diabetes for women with GDM.MethodsWe systematically searched the major electronic databases with no language restrictions. Two reviewers independently...

Nutritional Manipulation for the Primary Prevention of Gestational Diabetes Mellitus: A Meta-Analysis of Randomised Studies

Introduction The rise in gestational diabetes (GDM), defined as first onset or diagnosis of diabetes in pregnancy, is a global problem. GDM is often associated with unhealthy diet and is a major contributor to adverse outcomes maternal and fetal outcomes. Manipulation of nutrition has the potential to prevent GDM. Methods We assessed the effects of nutritional manipulation in...

Maternal Genotype and Severe Preeclampsia: A HuGE Review

affiliations: Women’s Health Research Unit, Barts and the London School of Medicine and Dentistry, Queen Mary University London, London, United Kingdom (Fiona M. Fong, Shakila Thangaratinam); Centre of Primary ... London, London, United Kingdom (Shakila Thangaratinam, Robert T. Walton). The preliminary results of this work were presented at the annual British Maternal and Fetal Medicine Society in Glasgow, United

Study protocol: differential effects of diet and physical activity based interventions in pregnancy on maternal and fetal outcomes—individual patient data (IPD) meta-analysis and health economic evaluation

Background Pregnant women who gain excess weight are at risk of complications during pregnancy and in the long term. Interventions based on diet and physical activity minimise gestational weight gain with varied effect on clinical outcomes. The effect of interventions on varied groups of women based on body mass index, age, ethnicity, socioeconomic status, parity, and underlying...

Estimation of proteinuria as a predictor of complications of pre-eclampsia: a systematic review

. Additional material Additional file 1 Additional file 2 Acknowledgements The members of the TIPPS (Tests In Prediction of Pre-eclampsia's Severity) review group are: Shakila Thangaratinam (Clinical Lecturer

A review of the methodological features of systematic reviews in maternal medicine

Background In maternal medicine, research evidence is scattered making it difficult to access information for clinical decision making. Systematic reviews of good methodological quality are essential to provide valid inferences and to produce usable evidence summaries to guide management. This review assesses the methodological features of existing systematic reviews in maternal...

Tests for predicting complications of pre-eclampsia: A protocol for systematic reviews

5177680). All authors read and approved the final manuscript. Acknowledgements TIPPS review group Shakila Thangaratinam (Clinical Lecturer), Khalid S Khan (Professor in Obstetrics and Gynaecology

Teaching trainers to incorporate evidence-based medicine (EBM) teaching in clinical practice: the EU-EBM project

Background Evidence based medicine (EBM) is considered an integral part of medical training, but integration of teaching various EBM steps in everyday clinical practice is uncommon. Currently EBM is predominantly taught through theoretical courses, workshops and e-learning. However, clinical teachers lack confidence in teaching EBM in workplace and are often unsure of the...

Erratum to: Study protocol: differential effects of diet and physical activity based interventions in pregnancy on maternal and fetal outcomes: individual patient data (IPD) meta-analysis and health economic evaluation

Tracy Roberts Richard D. Riley 0 Arri Coomarasamy Khalid S. Khan Ben Willem Mol Shakila Thangaratinam 0 School of Health and Population Sciences, College of Medical and Dental Sciences, University of ... Renault, Linda Reme Sagedal, Ingvild Vistad, Signe Nilssen Stafne, Siv Mørkved, Kjell Åsmund Salvesen, Christina Vinter, Marcia Vitolo, Arne Astrup, Nina Rica Wium Geiker and Shakila Thangaratinam. The

How are "teaching the teachers" courses in evidence based medicine evaluated? A systematic review

Background Teaching of evidence-based medicine (EBM) has become widespread in medical education. Teaching the teachers (TTT) courses address the increased teaching demand and the need to improve effectiveness of EBM teaching. We conducted a systematic review of assessment tools for EBM TTT courses. To summarise and appraise existing assessment methods for teaching the teachers...