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Factors associated with residents’ contract behavior with family doctors in community health service centers: A longitudinal survey from China

. Project administration: Rongrong He, Jun Wu. Writing ? original draft: Jiaoling Huang, Shanshan Liu. Writing ? review & editing: Jiaoling Huang. 13 / 16 14 / 16 15 / 16 1. Liu W. Health sector, the next

Effects of transversus abdominis plane blocks after hysterectomy: a meta-analysis of randomized controlled trials

Effects of transversus abdominis plane blocks after hysterectomy: a meta-analysis of randomized controlled trials Hong Zhou,1,* Xuefeng Ma,1,* Jinghua Pan,2 Hanlin Shuai,1 Shanshan Liu,3 Xin Luo,1

Application of weighted gene co-expression network analysis to identify key modules and hub genes in oral squamous cell carcinoma tumorigenesis

, Shanshan Liu, Haiyun Huang, Minqi Li Department of Bone Metabolism, School of Stomatology, Shandong University, Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, China *These authors

The critical roles of activated stellate cells-mediated paracrine signaling, metabolism and onco-immunology in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignant diseases worldwide. It is refractory to conventional treatments, and consequently has a documented 5-year survival rate as low as 7%. Increasing evidence indicates that activated pancreatic stellate cells (PSCs), one of the stromal components in tumor microenvironment (TME), play a crucial part in the...

Mesenchymal stem cells alleviate experimental autoimmune cholangitis through immunosuppression and cytoprotective function mediated by galectin-9

BackgroundMesenchymal stem cells (MSCs) play an anti-inflammatory role by secreting certain bioactive molecules to exert their therapeutic effects for disease treatment. However, the underlying mechanism of MSCs in chronic autoimmune liver diseases—primary biliary cholangitis (PBC), for example—remains to be elucidated.MethodsHuman umbilical cord–derived MSCs (UC-MSCs) were...

Mesenchymal stem cells alleviate experimental autoimmune cholangitis through immunosuppression and cytoprotective function mediated by galectin-9

Mesenchymal stem cells (MSCs) play an anti-inflammatory role by secreting certain bioactive molecules to exert their therapeutic effects for disease treatment. However, the underlying mechanism of MSCs in chronic autoimmune liver diseases—primary biliary cholangitis (PBC), for example—remains to be elucidated. Human umbilical cord–derived MSCs (UC-MSCs) were injected...

Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review

Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review Shuwen Han,1 Jianlan Gao,1 Qing Zhou,2 Shanshan Liu,3 Caixia Wen,3 Xi Yang4 1Department of Medical

A Novel Classification Indicator of Type 1 and Type 2 Diabetes in China

Because of the differences of treatment, it is extremely important to classify the types of diabetes, especially for the diagnosis made by clinician. In this study, we proposed a novel scheme calculating an indicator of classifying diabetes, which contains two stages: the first is a model of feature extraction, 17 features are automatically extracted from the curve of glucose...

Dual function of peroxiredoxin I in lipopolysaccharide-induced osteoblast apoptosis via reactive oxygen species and the apoptosis signal-regulating kinase 1 signaling pathway

Lipopolysaccharide (LPS)-induced osteoblast apoptosis is a prominent factor to the defect in periodontal tissue repair in periodontal disease. LPS challenge contributes to the production of reactive oxygen species (ROS) in periodontitis, and peroxiredoxin 1 (Prx1) is an antioxidant protein that protect cells against oxidative damage from ROS. Without LPS stimulation, apoptotic...

Previously claimed male germline stem cells from porcine testis are actually progenitor Leydig cells

BackgroundMale germline stem cells (mGSCs) offer great promise in regenerative medicine and animal breeding due to their capacity to maintain self-renewal and to transmit genetic information to the next generation following spermatogenesis. Human testis-derived embryonic stem cell-like cells have been shown to possess potential of mesenchymal progenitors, but there remains...

Magnetic alginate microspheres detected by MRI fabricated using microfluidic technique and release behavior of encapsulated dual drugs

Magnetic alginate microspheres detected by MRI fabricated using microfluidic technique and release behavior of encapsulated dual drugs Qin Wang,1 Shanshan Liu,1 Fan Yang,2 Lu Gan,3 Xiangliang Yang,3

STX2 promotes colorectal cancer metastasis through a positive feedback loop that activates the NF-κB pathway

Zhao, Jiaxin Bi, Wenting Wei, Shanshan Liu, Junfeng Qiu, Tingting Li, Li Liang, Yaping Ye, Wenting Liao & Yanqing DingDepartment of Pathology, School of Basic Medical Sciences, Southern Medical ... University, Guangzhou, Guangdong, ChinaYongxia Wang, Honghai Xu, Hongli Jiao, Shuyang Wang, Zhiyuan Xiao, Yali Zhao, Jiaxin Bi, Wenting Wei, Shanshan Liu, Junfeng Qiu, Tingting Li, Li Liang, Yaping Ye, Wenting

Locus-specific Retention Predictor (LsRP): A Peptide Retention Time Predictor Developed for Precision Proteomics

The precision prediction of peptide retention time (RT) plays an increasingly important role in liquid chromatography–tandem mass spectrometry (LC–MS/MS) based proteomics. Owing to the high reproducibility of liquid chromatography, RT prediction provides promising information for both identification and quantification experiment design. In this work, we present a Locus-specific...

Clinical investigation into the initial diagnosis and treatment of 539 patients with stage IV lung cancer

Clinical investigation into the initial diagnosis and treatment of 539 patients with stage IV lung cancer Qian Shao, Shanshan Liu, Wei Wang, Yingjie Zhang, Fengxiang Li, Jianbin Li Department of

Cost-effectiveness of Drugs to Treat Relapsed/Refractory Multiple Myeloma in the United States

Shanshan Liu Elizabeth T. Russo Steven D. Pearson Elizabeth D. Brouwer Daniel A. Ollendorf BACKGROUND: New 3-drug regimens have been developed and approved to treat multiple myeloma (MM). The absence of ... , Pharmaceutical Outcomes Research and Policy Program, University of Washington, Seattle. RICHARD H. CHAPMAN, PhD, MS; PATRICIA G. SYNNOTT, MS, MALD; SHANSHAN LIU, MS; ELIZABETH T. RUSSO, MD; STEVEN D. PEARSON, MD

Shapley Value for Parallel Machine Sequencing Situation without Initial Order

, China Received 27 July 2014; Accepted 5 October 2014 Academic Editor: Dongdong Ge Copyright © 2015 Shanshan Liu and Zhaohui Liu. This is an open access article distributed under the Creative Commons

Shapley Value for Parallel Machine Sequencing Situation without Initial Order

, China Received 27 July 2014; Accepted 5 October 2014 Academic Editor: Dongdong Ge Copyright © 2015 Shanshan Liu and Zhaohui Liu. This is an open access article distributed under the Creative Commons

The Effect of Iron Fortification on Iron (Fe) Status and Inflammation: A Randomized Controlled Trial

Background Iron deficiency (ID) is common in toddlers in developing countries. Iron fortified or meat-based complementary foods may be effective to prevent ID. Objective Our objective was to compare iron status at 18 months and growth from 6 to 18 months in rural poor toddlers fed 3 different complementary foods. Methods The study was nested within a larger trial in which 6-month...

Comparison of tripterygium wilfordii multiglycosides and tacrolimus in the treatment of idiopathic membranous nephropathy: a prospective cohort study

Background Idiopathic membranous nephropathy (IMN) is a major cause of nephrotic syndrome among adults. Considering the natural course of IMN, when to treat and with which immunosuppressive treatment need to be carefully considered in such patients. A combination of tripterygium wilfordii multiglycosides (TWG) and prednisone may be an effective option for treating patients with...