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A new technique for nanoparticle transport and its application in a novel nano-sieve

A new technique is proposed to transport and further classify nanoparticles of different sizes. A graphene sheet is used as the substrate; a nanoparticle is placed on the substrate and a sliding block is located below the substrate. As the sliding block moves under the graphene substrate, a driving force is yielded from the van der Waals interaction between the sliding block and...

The c-Myc-regulated lncRNA NEAT1 and paraspeckles modulate imatinib-induced apoptosis in CML cells

Chronic myeloid leukemia (CML) is a clonal disease characterized by the presence of the constitutively active tyrosine kinase BCR-ABL oncoprotein. Although BCR-ABL is crucially important for pathogenesis and treatment response, it is thought that some additional factors might be involved in the regulation of these processes. Aberrant expression of long noncoding RNAs (lncRNAs...

The soil seed bank of a rehabilitated draw-down zone and its similarity to standing vegetation in the Three Gorges Reservoir Area

The reverse seasonal flooding that resulted from the construction of the Three Gorges Project has induced a drastic degradation of draw-down zone vegetation and the seed bank in the reservoir. The composition and distribution of seed banks and their similarities to standing vegetation were determined through field investigations and germination experiments on the vegetation as...

A Hybrid Multiobjective Discrete Particle Swarm Optimization Algorithm for Cooperative Air Combat DWTA

A hybrid multiobjective discrete particle swarm optimization (HMODPSO) algorithm is proposed to solve cooperative air combat dynamic weapon target assignment (DWTA). First, based on the threshold of damage probability and time window constraints, a new cooperative air combat DWTA multiobjective optimization model is presented, which employs the maximum of the target damage...

The effects of the reverse seasonal flooding on soil texture within the hydro-fluctuation belt in the Three Gorges reservoir, China

Purpose The formation of the large hydro-fluctuation belt at the altitude of 145–175 m, following the construction of the Three Gorges Dam, developed from the terrestrial system in the Three Gorges reservoir. This research mainly concerned the effects of the resultant reverse seasonal flooding on soil texture. Materials and methods Four field experimental plots were designed with...

Motion Driven by Strain Gradient Fields

AffiliationsLNM, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, ChinaChao Wang & Shaohua Chen AuthorsSearch for Chao Wang in:Nature Research journals • PubMed • Google ScholarSearch for ... Shaohua Chen in:Nature Research journals • PubMed • Google Scholar Contributions S.H.C. conceived the original idea, designed and supervised the simulations. C.W. formulated the numerical model and drafted

Effects of the seasonal flooding on riparian soil seed bank in the Three Gorges Reservoir Region: a case study in Shanmu River

Introduction The water-level fluctuation in the Three Gorges Reservoir Region has changed dramatically as a result of the hydroelectric project for flood control and power generation. The riparian seasonal hydrological environment also has changed from summer flooding with winter drought to summer drought with winter flooding. The changes of riparian seed bank and vegetation were...

Oligoclonal expansion of TCR Vδ T cells may be a potential immune biomarker for clinical outcome of acute myeloid leukemia

Background Recent data have shown that γδ T cells can act as mediators for immune defense against tumors. Our previous study has demonstrated that persisting clonally expanded TRDV4 T cells might be relatively beneficial for the outcome of patients with T cell acute lymphoblastic leukemia after hematopoietic stem cell transplantation (HSCT). However, little is known about the...

Characterizing Urban Household Waste Generation and Metabolism Considering Community Stratification in a Rapid Urbanizing Area of China

The relationship between social stratification and municipal solid waste generation remains uncertain under current rapid urbanization. Based on a multi-object spatial sampling technique, we selected 191 households in a rapidly urbanizing area of Xiamen, China. The selected communities were classified into three types: work-unit, transitional, and commercial communities in the...

Pathways related to PMA-differentiated THP1 human monocytic leukemia cells revealed by RNA-Seq

Previous analyses have reported that the human monocytic cell line THP1 can be differentiated into cells with macrophage-like characteristics by phorbol 12-myristate 13-acetate (PMA). However, little is known about the mechanism responsible for regulating this differentiation process. Here, we performed high-throughput RNA-Seq analysis to investigate the genes differently...

Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia

Background Acute promyelocytic leukemia (APL) is associated with chromosomal translocation t(15;17), which results in the proliferation of morphologically abnormal promyelocytes. Gain of supernumerary copies of the 8q24 chromosomal region, which harbors MYC and PVT1, has been shown to be the most common secondary alteration in human APL. Increased MYC can accelerate the...

Fucoidan Induces Cancer Cell Apoptosis by Modulating the Endoplasmic Reticulum Stress Cascades

Background Cancer metastasis is the main cause leading to disease recurrence and high mortality in cancer patients. Therefore, inhibiting metastasis process or killing metastatic cancer cells by inducing apoptosis is of clinical importance in improving cancer patient survival. Previous studies revealed that fucoidan, a fucose-rich polysaccharide isolated from marine brown alga...

Molecular alterations in the TCR signaling pathway in patients with aplastic anemia

Background A previous study has demonstrated a significantly increased CD3ζ gene expression level in aplastic anemia (AA). However, the mechanism underlying the upregulated CD3ζ mRNA expression level and that of T cell activation signaling molecules in AA patients remains unclear. Thus, we investigated the expression levels of the CD3ζ, CD28, CTLA-4, and Cbl-b genes, the SNP...

Synthesis of Ag3PO4–AgBr with a novel heterostructure, and its photocatalytic properties

Ag3PO4–AgBr nanocomposites with a novel heterostructure were synthesized by a simple one-step reaction at room temperature with cetyltrimethylammonium bromide as surfactant and bromine source. The nanocomposites comprise uniform, monodisperse nanospheres of average diameter 90 nm. AgBr nanoparticles are present both on the surface and inside the nanospheres. The morphology of the...

Development of a Freeze-Dried Fungal Wettable Powder Preparation Able to Biodegrade Chlorpyrifos on Vegetables

Continuous use of the pesticide chlorpyrifos has resulted in harmful contaminations in environment and species. Based on a chlorpyrifos-degrading fungus Cladosporium cladosporioides strain Hu-01 (collection number: CCTCC M 20711), a fungal wettable powder preparation was developed aiming to efficiently remove chlorpyrifos residues from vegetables. The formula was determined to be...

A global count of the extreme poor in 2012: data issues, methodology and initial results

The 2014 release of a new set of purchasing power parity (PPP) conversion factors (PPPs) for 2011 has prompted a revision of the World Bank’s international poverty line. In revising the line, we have sought to minimize changes to the real purchasing power of the earlier $1.25 line (in 2005 PPPs), so as to preserve the integrity of the goalposts for international targets such as...

Layer-by-Layer Assembly and Photocatalytic Activity of Titania Nanosheets on Coal Fly Ash Microspheres

In order to address the problem with titania distribution and recovery, series of Ti0.91O2/CFA photocatalysts (Ti0.91O2/CFA-, and ) were fabricated by assembling Ti0.91O2 nanosheets on coal fly ash (CFA) microspheres via the layer-by-layer assembly (LBLA) process and characterized by scanning electron microscopy (SEM), X-ray diffraction analysis (XRD), N2-sorption, and...

The Prevalence of Helicobacter pylori Infection Decreases with Older Age in Atrophic Gastritis

© 2013 Shaohua Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided ... metaplasia ED: Epithelial dysplasia.Authors’ Contribution Lixiong Ying and Shaohua Chen contributed equally to this work. Acknowledgments This study was supported by Traditional Chinese Medicine Program of