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Image-based promoter prediction: a promoter prediction method based on evolutionarily generated patterns

Prediction of promoter regions is crucial for studying gene function and regulation. The well-accepted position weight matrix method for this purpose relies on predefined motifs, which would hinder application across different species. Here, we introduce image-based promoter prediction (IBPP) as a method that creates an “image” from training promoter sequences using an...

Identification of co-expression modules and pathways correlated with osteosarcoma and its metastasis

for the molecular mechanisms of osteosarcoma. Notes Jian-sheng Wang and Yun-guo Wang contributed equally to this work. Abbreviations GEO:  Gene Expression Omnibus GO:  Gene Ontology KEGG

Effect of ZFN-edited myostatin loss-of-function mutation on gut microbiota in Meishan pigs

Li. Methodology: Sheng-Wang Jiang, Li-Li Qian, Chun-Bo Cai. Project administration: Wen-Tao Cui, Shan-Shan Xie, Ting Gao. Resources: Kui Li. Writing ? original draft: Wen-Tao Cui, Gao-Jun Xiao

Optimized Parameter Settings of Binary Bat Algorithm for Solving Function Optimization Problems

-Sheng Wang; moc.621@gnehseij_gnaw Received 7 October 2017; Accepted 11 April 2018; Published 14 May 2018 Academic Editor: Jit S. Mandeep Copyright © 2018 Xiao-Xu Ma and Jie-Sheng Wang. This is an open ... collection, analysis, algorithm simulation, draft writing, and critical revision of this paper. Jie-Sheng Wang participated in the concept, design and interpretation and commented on the manuscript

Remission of HIV-related naïve and high-risk Burkitt’s lymphoma treated by autologous stem cell transplantation plus cART

A 27-year-old male with HIV-associated naïve and high-risk Burkitt’s lymphoma sequentially received short-term, high-dose non-myeloablative chemotherapy and autologous CD34-positive stem cell transfusion in the setting of combined antiretroviral therapy (cART). Prompt hematopoietic recovery was observed after 2 weeks and clinical remission from Burkitt’s lymphoma within...

Fast sparsity adaptive matching pursuit algorithm for large-scale image reconstruction

The accurate reconstruction of a signal within a reasonable period is the key process that enables the application of compressive sensing in large-scale image transmission. The sparsity adaptive matching pursuit (SAMP) algorithm does not need prior knowledge on signal sparsity and has high reconstruction accuracy but has low reconstruction efficiency. To overcome the low...

Explicit bounds of unknown function of some new weakly singular retarded integral inequalities for discontinuous functions and their applications

The purpose of the present paper is to establish some new retarded weakly singular integral inequalities of Gronwall-Bellman type for discontinuous functions, which generalize some known weakly singular and impulsive integral inequalities. The inequalities given here can be used in the analysis of the qualitative properties of certain classes of singular differential equations...

Chaperonin 60 sustains osteoblast autophagy and counteracts glucocorticoid aggravation of osteoporosis by chaperoning RPTOR

, Chang Gung University College of Medicine, Kaohsiung, TaiwanJih-Yang KoGraduate Institute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiung, TaiwanFeng-Sheng Wang ... Chung-Wen Kuo in:Nature Research journals • PubMed • Google Scholar Search for Feng-Sheng Wang in:Nature Research journals • PubMed • Google Scholar Contributions Study conception and design: WS Lian

Efficacy and Safety of a Formulated Herbal Granula, Jiu Wei Zhen Xin, for Generalized Anxiety Disorder: A Meta-Analysis

, China Correspondence should be addressed to Xin-jian Qiu; nc.ude.usc@yxjxuiq Sheng Wang and Lin-lin Zhao contributed equally to this work. Received 23 August 2017; Revised 21 November 2017; Accepted 4 ... December 2017; Published 7 March 2018 Academic Editor: Khalid Rahman Copyright © 2018 Sheng Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which

Efficacy and Safety of a Formulated Herbal Granula, Jiu Wei Zhen Xin, for Generalized Anxiety Disorder: A Meta-Analysis

, China Correspondence should be addressed to Xin-jian Qiu; nc.ude.usc@yxjxuiq Sheng Wang and Lin-lin Zhao contributed equally to this work. Received 23 August 2017; Revised 21 November 2017; Accepted 4 ... December 2017; Published 7 March 2018 Academic Editor: Khalid Rahman Copyright © 2018 Sheng Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which

Antibodies from a Patient with Type 1 Diabetes and Celiac Disease Bind to Macrophages that Express the Scavenger Receptor CD163

Can J Gastroenterol Antibodies from a patient with type 1 diabetes and celiac disease bind to macrophages that express the scavenger receptor CD163 Brigitte Sonier MSc Alexander Strom Gen-Sheng Wang

Antibodies from a Patient with Type 1 Diabetes and Celiac Disease Bind to Macrophages that Express the Scavenger Receptor CD163

Can J Gastroenterol Antibodies from a patient with type 1 diabetes and celiac disease bind to macrophages that express the scavenger receptor CD163 Brigitte Sonier MSc Alexander Strom Gen-Sheng Wang

Self-shedding and sweeping of condensate on composite nano-surface under external force field: enhancement mechanism for dropwise and filmwise condensation modes

Sheng Wang In this work, we propose the concept to use the hydrophilic or neutral surface for condensation heat transfer and to use the superhydrophobic surface for enhancement by self-shedding and

Using ROS as a Second Messenger, NADPH Oxidase 2 Mediates Macrophage Senescence via Interaction with NF-κB during Pseudomonas aeruginosa Infection

Pseudomonas aeruginosa (PA) is one of the most prevalent pathogens that cause nosocomial infection in critical patients. However, the mechanisms underlying macrophage growth status and functional changes during PA infection are yet unknown. In the present study, NADPH oxidase, gp91phox (NOX2) mediated macrophage to senescence in a PAO1 colony-dependent manner. gp91phox might...

Using ROS as a Second Messenger, NADPH Oxidase 2 Mediates Macrophage Senescence via Interaction with NF-κB during Pseudomonas aeruginosa Infection

Pseudomonas aeruginosa (PA) is one of the most prevalent pathogens that cause nosocomial infection in critical patients. However, the mechanisms underlying macrophage growth status and functional changes during PA infection are yet unknown. In the present study, NADPH oxidase, gp91phox (NOX2) mediated macrophage to senescence in a PAO1 colony-dependent manner. gp91phox might...

Neural Mechanisms of Autonomic Dysfunction in Neurological Diseases

reviewers for their support and constructive critiques in making this special issue possible. De-Pei Li Yu-Long Li Jianhua Li Sheng Wang References D. P. Li and H. L. Pan, “Glutamatergic regulation of

Neural Mechanisms of Autonomic Dysfunction in Neurological Diseases

reviewers for their support and constructive critiques in making this special issue possible. De-Pei Li Yu-Long Li Jianhua Li Sheng Wang References D. P. Li and H. L. Pan, “Glutamatergic regulation of

Neural Mechanisms of Autonomic Dysfunction in Neurological Diseases

reviewers for their support and constructive critiques in making this special issue possible. De-Pei Li Yu-Long Li Jianhua Li Sheng Wang [2] A. M. Allen, ?Inhibition of the hypothalamic paraventricular

Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence

BackgroundCell therapy for the treatment of intervertebral disc degeneration (IDD) faces serious barriers since tissue-specific adult cells such as nucleus pulposus cells (NPCs) have limited proliferative ability and poor regenerative potential; in addition, it is difficult for exogenous adult stem cells to survive the harsh environment of the degenerated intervertebral disc...

Technological and economic perspectives for development and manufacturing of cathode materials for lithium-ion batteries for transport industry

Energy accumulators are one of the key directions of research and applied development in the spheres of power generation, saving and efficiency. Lithium-ion batteries (LIB) are widely used in portable power sources for modern electronics. However, currently the most perspective sphere of their use is transport industry. In this article we discuss the perspectives of using LIB in...