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18 papers found.
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Prediction of major depressive episodes and suicide-related ideation over a 3-year interval among Japanese undergraduates

: Satoshi Asakura. Software: Nobuyuki Mitsui. Supervision: Satoshi Asakura, Keisuke Takanobu, Shinya Watanabe, Kuniyoshi Toyoshima, Yuki Kako, Ichiro Kusumi. Validation: Keisuke Takanobu, Shinya Watanabe

Predictability of Intraocular Lens Power Calculation for Cataract with Keratoconus: A Multicenter Study

Research journals • PubMed • Google Scholar Search for Jun Shimazaki in:Nature Research journals • PubMed • Google Scholar Search for Shinya Watanabe in:Nature Research journals • PubMed • Google Scholar

Impaired social cognition in anorexia nervosa patients

Impaired social cognition in anorexia nervosa patients Sayo Hamatani,1 Masahito Tomotake,2 Tomoya Takeda,1 Naomi Kameoka,3 Masashi Kawabata,3 Hiroko Kubo,3 Yukio Tada,3 Yukiko Tomioka,4 Shinya

A case-matched study of stereotactic radiosurgery for patients with brain metastases: comparing treatment results for those with versus without neurological symptoms

We aimed to reappraise whether post-stereotactic radiosurgery (SRS) results for brain metastases differ between patients with and without neurological symptoms. This was an institutional review board-approved, retrospective cohort study using our prospectively accumulated database including 2825 consecutive BM patients undergoing gamma knife SRS alone during the 15-year period...

Complete Genome Sequence of Streptococcus dysgalactiae subsp. equisimilis 167 Carrying Lancefield Group C Antigen and Comparative Genomics of S. dysgalactiae subsp. equisimilis Strains

Shinya Watanabe 0 Teruo Kirikae 0 Tohru Miyoshi-Akiyama 0 0 Department of Infectious Diseases, National Center for Global Health and Medicine , Shinjuku-ku, Tokyo, Japan Streptococcus dysgalactiae

Concomitant Regulation of Host Tissue-Destroying Virulence Factors and Carbohydrate Metabolism During Invasive Diseases Induced by Group G Streptococci

Background. Streptococcus dysgalactiae subsp. equisimilis (SDSE) has Lancefield group G or C antigens. Recent epidemiological studies reveal that invasive SDSE infections have been increasing in Asia, Europe, and the United States. The mechanisms and key virulence factors by which SDSE causes invasive diseases are poorly understood. Methods. We analyzed the SDSE transcriptome in...

Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture

Kazumasa Yoshida Shuhei Yasukouchi Satoko Osano Shinya Watanabe Masahiro Aizawa Takashi Yugawa Tohru Kiyono Hitoshi Kurumizaka Yasuyuki Ohkawa Masatoshi Fujita Efficient pre-replication complex (pre-RC

Remote Cerebellar Hemorrhage after Removal of a Supratentorial Glioma without Perioperative CSF Loss: A Case Report

A 44-year-old man presented with the rare complication of remote cerebellar hemorrhage (RCH) after removal of a supratentorial glioma without the loss of a large volume of cerebrospinal fluid (CSF). He presented with severe headache, nausea, and vomiting for a few days, then he developed neurological deterioration including progressive disturbance of consciousness and left...

Remote Cerebellar Hemorrhage after Removal of a Supratentorial Glioma without Perioperative CSF Loss: A Case Report

A 44-year-old man presented with the rare complication of remote cerebellar hemorrhage (RCH) after removal of a supratentorial glioma without the loss of a large volume of cerebrospinal fluid (CSF). He presented with severe headache, nausea, and vomiting for a few days, then he developed neurological deterioration including progressive disturbance of consciousness and left...

Comparison of DNA methylation levels of repetitive loci during bovine development

Background DNA methylation of cytosine residues in CpG dinucleotide controls gene expression and dramatically changes during development. Its pattern is disrupted in cloned animals suggesting incomplete reprogramming during somatic cell nuclear transfer (the first reprogramming). However, the second reprogramming occurs in the germ cells and epigenetic errors in somatic cells of...

Phylogenetic and Structural Diversity in the Feline Leukemia Virus Env Gene

Feline leukemia virus (FeLV) belongs to the genus Gammaretrovirus, and causes a variety of neoplastic and non-neoplastic diseases in cats. Alteration of viral env sequences is thought to be associated with disease specificity, but the way in which genetic diversity of FeLV contributes to the generation of such variants in nature is poorly understood. We isolated FeLV env genes...

Fumarate Reductase Activity Maintains an Energized Membrane in Anaerobic Mycobacterium tuberculosis

Oxygen depletion of Mycobacterium tuberculosis engages the DosR regulon that coordinates an overall down-regulation of metabolism while up-regulating specific genes involved in respiration and central metabolism. We have developed a chemostat model of M. tuberculosis where growth rate was a function of dissolved oxygen concentration to analyze metabolic adaptation to hypoxia. A...

Type IV SCCmec found in decade old Brazilian MRSA isolates

Methicillin-resistant Staphylococcus aureus (MRSA) commonly causes infection in hospitalized patients. Since its appearance in the 1960s, the SCCmec has evolved throughout the years into 5 different types (I-V), each bearing a different set of genes. Infection with MRSA SCCmec types I, II or III is almost exclusively restricted to hospitalised patients. However, recently...

Genetic Diversity of Staphylocoagulase Genes (coa): Insight into the Evolution of Variable Chromosomal Virulence Factors in Staphylococcus aureus

Background The production of staphylocoagulase (SC) causing the plasma coagulation is one of the important characteristics of Staphylococcus aureus. Although SCs have been classified into 10 serotypes based on the differences in the antigenicity, genetic bases for their diversities and relatedness to chromosome types are poorly understood. Methodology/Principal Findings We...

CREB-H: a novel mammalian transcription factor belonging to the CREB/ATF family and functioning via the box-B element with a liver-specific expression

The expression of liver-specific genes is regulated by unequivocally allocated transcription factors via proper responsible elements within their promoters. We identified a novel transcription factor, CREB-H, and found that its expression was restricted in the liver among 16 human tissues tested. A region of CREB-H exhibited significant homology to the basic leucine zipper (b-Zip...

The Human Anatomic Gene Expression Library (H-ANGEL), the H-Inv integrative display of human gene expression across disparate technologies and platforms

The Human Anatomic Gene Expression Library (H-ANGEL) is a resource for information concerning the anatomical distribution and expression of human gene transcripts. The tool contains protein expression data from multiple platforms that has been associated with both manually annotated full-length cDNAs from H-InvDB and RefSeq sequences. Of the H-Inv predicted genes, 18 897 have...

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

D. Terwilliger Per Unneberg Vamsi Veeramachaneni Shinya Watanabe Laurens Wilming Norikazu Yasuda Hyang-Sook Yoo Marvin Stodolsky Wojciech Makalowski Mitiko Go Kenta Nakai Toshihisa Takagi Minoru