integrity and validity of the data collected and analyzed. Author Contributions Conceptualization: Rick J. Jansen, Richard B. Hayes, Anthony B. Miller, Sholom Wacholder, Timothy R. Church. Formal analysis ... : Rick J. Jansen, Timothy R. Church. Funding acquisition: Timothy R. Church. Investigation: Rick J. Jansen, Bruce H. Alexander, Richard B. Hayes, Anthony B. Miller, Sholom Wacholder, Timothy R. Church
Background Time to first cigarette (TTFC) after waking is an indicator of nicotine dependence. The association between TTFC and chronic obstructive pulmonary disease (COPD), the third leading cause of death in the United States, has not yet been reported. Methods We investigated the cross-sectional association between TTFC and prevalent COPD among 6,108 current smokers in the...
SAFAEIAN SHOLOM WACHOLDER ALLAN HILDESHEIM
Sholom Wacholder 0 Meredith Yeager 0 Linda M. Liao 0 0 6120 Executive Boulevard , Suite 5050, MSC 7229, Rockville, MD 20852 ( Pleiotropy across the 8q24 region is perhaps the most intriguing of the ... , Bethesda, Maryland (Sholom Wacholder); National Cancer Institute, Core Genotyping Facility, SAIC-Frederick (Meredith Yeager); and Division of Cancer Epidemiology and Genetics, Occupational and Environmental
), and Sholom Wacholder (Statistician); at SAIC, NCIFrederick, Frederick, MD: Ligia Pinto (Head, HPV Immunology Laboratory) and Alfonso Garcia-Pineres (Scientist, HPV Immunology Laboratory); at Womens and
0 6120 Executive Blvd. , EPS 5050, MSC-7244, Rockville, MD 20892-7244 ( 1 Sholom Wacholder , Summer S. Han , Clarice R. Weinberg 2 Affiliations of authors: Biostatistics Branch, Division of Cancer
Nilanjan Chatterjee Sholom Wacholder Gene-environment-wide interaction studies of disease occurrence in human populations may be able to exploit the same agnostic approach to interrogating the human ... of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health, Department of Health and Human Services, Bethesda, Maryland (Nilanjan Chatterjee, Sholom Wacholder). This
coordinator), Mark Schiffman (medical monitor and NCI co-project officer), John T. Schiller (HPV virologist), Mark Sherman (QC pathologist), Diane Solomon (medical monitor and QC pathologist), Sholom Wacholder
The recent success of genome-wide association studies in finding susceptibility genes for many common diseases presents tremendous opportunities for epidemiologic studies of environmental risk factors. Analysis of gene-environment interactions, included in only a small fraction of epidemiologic studies until now, will begin to accelerate as investigators integrate analyses of...
smokers Stephanie A Kovalchik 0 Sara De Matteis Maria Teresa Landi Neil E Caporaso Ravi Varadhan Dario Consonni Andrew W Bergen Hormuzd A Katki Sholom Wacholder 0 Economics, Sociology, and Statistics
An important follow-up step after genetic markers are found to be associated with a disease outcome is a more detailed analysis investigating how the implicated gene or chromosomal region and an established environment risk factor interact to influence the disease risk. The standard approach to this study of gene–environment interaction considers one genetic marker at a time and...
of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland (Diane Solomon, Allan Hildesheim, Sholom Wacholder, Mark Schiffman); and Prevention and Implementation Group ... monitor and NCI co-Project Officer), John T. Schiller (HPV virologist), Mark Sherman (quality control pathologist), Diane Solomon (medical monitor and quality control pathologist), and Sholom Wacholder
limited, and the opportunities for benefit so great that all earnest approaches must be welcomed. MARK SCHIFFMAN NICOLAS WENTZENSEN SHOLOM WACHOLDER WALTER KINNEY JULIA C. GAGE PHILIP E. CASTLE
Mark Schiffman Nicolas Wentzensen Sholom Wacholder Walter Kinney Julia C. Gage Philip E. Castle Strong evidence now supports the adoption of cervical cancer prevention strategies that explicitly
Background Targeting smokers at higher lung cancer risk can improve efficiency and reduce false-positive detection in lung cancer screening. We evaluated whether time to first cigarette after waking (TTFC), a single-item measure of nicotine dependency, could improve stratification of lung cancer risk beyond standard smoking metrics (intensity, duration, and pack-years).
Background Vaginal pH is related to genital tract inflammation and changes in the bacterial flora, both suggested cofactors for persistence of human papillomavirus (HPV) infection. To evaluate the relationship between vaginal pH and HPV, we analyzed data from our large population-based study in Guanacaste, Costa Rica. We examined vaginal pH and the risk of HPV infection...
affiliations: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland (Sara De Matteis, Andrew W. Bergen, Neil E. Caporaso, Jay H. Lubin, Sholom Wacholder, Maria Teresa Landi