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Association of genetic polymorphisms in genes involved in Ara-C and dNTP metabolism pathway with chemosensitivity and prognosis of adult acute myeloid leukemia (AML)

advice; ZH, CSP, ZXL helped to collect specimen smoothly. All authors read and approved the final manuscript. Acknowledgements The authors would like to thank Prof. Hui Zeng, Shu-ping Chen, Xie-lan Zhao

Serum selenium level and gestational diabetes mellitus: a systematic review and meta-analysis

Background The association between serum selenium level and gestational diabetes mellitus (GDM) is controversial. The aim of our study was to systematically review available literature linking selenium to GDM for a comprehensive understanding of the relationship between serum selenium level and GDM in human. Methods PubMed, The Cochrane Library and Medline were searched for...

Serum selenium level and gestational diabetes mellitus: a systematic review and meta-analysis

The association between serum selenium level and gestational diabetes mellitus (GDM) is controversial. The aim of our study was to systematically review available literature linking selenium to GDM for a comprehensive understanding of the relationship between serum selenium level and GDM in human. PubMed, The Cochrane Library and Medline were searched for studies published up to...

Interleukin-6: an emerging regulator of pathological pain

Interleukin-6 is an inflammatory cytokine with wide-ranging biological effects. It has been widely demonstrated that neuroinflammation plays a critical role in the development of pathological pain. Recently, various pathological pain models have shown elevated expression levels of interleukin-6 and its receptor in the spinal cord and dorsal root ganglia. Additionally, the...

Interleukin-6: an emerging regulator of pathological pain

Interleukin-6 is an inflammatory cytokine with wide-ranging biological effects. It has been widely demonstrated that neuroinflammation plays a critical role in the development of pathological pain. Recently, various pathological pain models have shown elevated expression levels of interleukin-6 and its receptor in the spinal cord and dorsal root ganglia. Additionally, the...

Effect of Repeated Electroacupuncture Intervention on Hippocampal ERK and p38MAPK Signaling in Neuropathic Pain Rats

Results of our past studies showed that hippocampal muscarinic acetylcholine receptor (mAChR)-1 mRNA and differentially expressed proteins participating in MAPK signaling were involved in electroacupuncture (EA) induced cumulative analgesia in neuropathic pain rats, but the underlying intracellular mechanism remains unknown. The present study was designed to observe the effect of...

Effect of Repeated Electroacupuncture Intervention on Hippocampal ERK and p38MAPK Signaling in Neuropathic Pain Rats

Results of our past studies showed that hippocampal muscarinic acetylcholine receptor (mAChR)-1 mRNA and differentially expressed proteins participating in MAPK signaling were involved in electroacupuncture (EA) induced cumulative analgesia in neuropathic pain rats, but the underlying intracellular mechanism remains unknown. The present study was designed to observe the effect of...

Effect of Repeated Electroacupuncture Intervention on Hippocampal ERK and p38MAPK Signaling in Neuropathic Pain Rats

Results of our past studies showed that hippocampal muscarinic acetylcholine receptor (mAChR)-1 mRNA and differentially expressed proteins participating in MAPK signaling were involved in electroacupuncture (EA) induced cumulative analgesia in neuropathic pain rats, but the underlying intracellular mechanism remains unknown. The present study was designed to observe the effect of...

Involvement of hippocampal acetylcholinergic receptors in electroacupuncture analgesia in neuropathic pain rats

Cumulating evidence has shown a close correlation between electroacupuncture stimulation (EAS) frequency-specific analgesic effect and central opioid peptides. However, the actions of hippocampal acetylcholinergic receptors have not been determined. This study aims to observe the effect of different frequencies of EAS on the expression of hippocampal muscarinic and nicotinic...

Electroacupuncture Reduces the Effects of Acute Noxious Stimulation on the Electrical Activity of Pain-Related Neurons in the Hippocampus of Control and Neuropathic Pain Rats

Chen,3 Shu-Ping Chen,1 Yong-Hui Gao,1 Jian-Liang Zhang,1 Xiu-Mei Feng,1 Yaxia Yan,1 Jun-Ling Liu,1 Ingrid Gaischek,2 Daniela Litscher,2 Lu Wang,2 Irmgard Th. Lippe,4 and Gerhard Litscher1,2 1Department

Historical Review about Research on “Bonghan System” in China

, Lixia Zhu, and Chen Wen. The present paper was written by Jun-Ling Liu, Xiang-Hong Jing, Hong Shi, Shu-Ping Chen, Wei He, Wan-Zhu Bai, and Bing Zhu. Junling Liu and Xianghong Jing contributed equally to

Effect of Electroacupuncture Intervention on Expression of CGRP, SP, COX-1, and PGE2 of Dorsal Portion of the Cervical Spinal Cord in Rats with Neck-Incision Pain

-sheng Yang,1 Shu-ping Chen,2 Yong-hui Gao,2 Jian-liang Zhang,2 and Jun-ling Liu2 1Department of Biochemistry and Molecular Biology, Institute of Acu-Moxibustion, China Academy of Chinese Medical Sciences ... Li-na Qiao, Jun-ying Wang, Yong-sheng Yang, Shu-ping Chen, and Yong-hui Gao and Jian-liang Zhang. The present paper was written by Li-na Qiao and revised by Jun-ling Liu. Li-na Qiao and Jun-ying Wang

Effect of Electroacupuncture Intervention on Expression of CGRP, SP, COX-1, and PGE2 of Dorsal Portion of the Cervical Spinal Cord in Rats with Neck-Incision Pain

-sheng Yang,1 Shu-ping Chen,2 Yong-hui Gao,2 Jian-liang Zhang,2 and Jun-ling Liu2 1Department of Biochemistry and Molecular Biology, Institute of Acu-Moxibustion, China Academy of Chinese Medical Sciences ... Li-na Qiao, Jun-ying Wang, Yong-sheng Yang, Shu-ping Chen, and Yong-hui Gao and Jian-liang Zhang. The present paper was written by Li-na Qiao and revised by Jun-ling Liu. Li-na Qiao and Jun-ying Wang