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A modular bottom-up approach for constructing physical input–output tables (PIOTs) based on process engineering models

Physical input–output tables (PIOTs) were first conceptualized in the 1990s but have not been widely adopted. However, with the increased emphasis on building a circular economy and understanding the resource nexus, PIOTs will become critical for optimizing resource flows and restructuring economies to close material loops. This necessitates a focus on improved methodologies for...

Genome-wide association mapping of spot blotch resistance in wheat association mapping initiative (WAMI) panel of spring wheat (Triticum aestivum L.)

, Dwijesh Chandra Mishra. Supervision: Vinod Kumar Mishra, Ramesh Chand, Arun Kumar Joshi. Validation: Ram Narayan Ahirwar, Shweta Singh. Visualization: Ram Narayan Ahirwar, Sundeep Kumar. Writing ... ? original draft: Ram Narayan Ahirwar. Writing ? review & editing: Vinod Kumar Mishra, Ramesh Chand, Neeraj Budhlakoti, Sundeep Kumar, Shweta Singh, Arun Kumar Joshi. 12 / 14 11. 13 / 14 1. Reynolds M

Labile hemoglobin A1c: A factor affecting the estimation of glycated hemoglobin

JOURNAL OF CLINICAL AND EXPERIMENTAL INVESTIGATIONS Labile hemoglobin A : A factor affecting the estimation 1c of glycated hemoglobin Kalpana Singh 0 Bhawna Mahajan 1 Shweta Singh 2 Abbas Ali Mahdi

Comprehensive in silico allergenicity assessment of novel protein engineered chimeric Cry proteins for safe deployment in crops

Development of chimeric Cry toxins by protein engineering of known and validated proteins is imperative for enhancing the efficacy and broadening the insecticidal spectrum of these genes. Expression of novel Cry proteins in food crops has however created apprehensions with respect to the safety aspects. To clarify this, premarket evaluation consisting of an array of analyses to...

International tuberculosis research collaborations within Asia

BackgroundAsia bears more than half the global tuberculosis (TB) burden. Economic development in the region has increased available funding for biomedical research and opportunity for collaboration. We explored the extent of international tuberculosis research collaborations between institutions within Asia.MethodsWe conducted a Pubmed search for all articles with tuberculosis in...

International tuberculosis research collaborations within Asia

Asia bears more than half the global tuberculosis (TB) burden. Economic development in the region has increased available funding for biomedical research and opportunity for collaboration. We explored the extent of international tuberculosis research collaborations between institutions within Asia. We conducted a Pubmed search for all articles with tuberculosis in the title...

Nitric oxide has contrasting age-dependent effects on the functionality of murine hematopoietic stem cells

Background The success of hematopoietic stem cell (HSC) transplantation is dependent on the quality of the donor HSCs. Some sources of HSCs display reduced engraftment efficiency either because of inadequate number (e.g., fetal liver and cord blood), or age-related dysfunction (e.g. in older individuals). Therefore, use of pharmacological compounds to improve functionality of...

Schrodinger’s scat: a critical review of the currently available tiger (Panthera Tigris) and leopard (Panthera pardus) specific primers in India, and a novel leopard specific primer

specific primer Pranay Amruth Maroju 0 Sonu Yadav 0 Vishnupriya Kolipakam Shweta Singh Qamar Qureshi Yadvendradev Jhala 0 Equal contributors Wildlife Institute of India , Chandrabani, Dehradun 248001

Phytochemicals Mediated Remediation of Neurotoxicity Induced by Heavy Metals

traditional medicinal plants. Conflict of Interests The authors report no declarations of interests. Acknowledgments Vivek Kumar Gupta and Shweta Singh are grateful to the University Grant Commission, New Delhi

Frequency of CFTR, SPINK1, and Cathepsin B Gene Mutation in North Indian Population: Connections between Genetics and Clinical Data

Received 30 August 2013; Accepted 7 November 2013; Published 27 January 2014 Academic Editors: M. Edery and B. Sharma Copyright © 2014 Shweta Singh et al. This is an open access article distributed under ... that there is no conflict of interests regarding the publication of this paper. Acknowledgments The author (Shweta Singh) acknowledges the financial support from Government of India in the form of DST

Frequency of CFTR, SPINK1, and Cathepsin B Gene Mutation in North Indian Population: Connections between Genetics and Clinical Data

Received 30 August 2013; Accepted 7 November 2013; Published 27 January 2014 Academic Editors: M. Edery and B. Sharma Copyright © 2014 Shweta Singh et al. This is an open access article distributed under ... . Conflict of Interests The authors declare that there is no conflict of interests regarding the publication of this paper. Acknowledgments The author (Shweta Singh) acknowledges the financial support from

Attachment Site Selection and Identity in Bxb1 Serine Integrase-Mediated Site-Specific Recombination

Phage-encoded serine integrases mediate directionally regulated site-specific recombination between short attP and attB DNA sites without host factor requirements. These features make them attractive for genome engineering and synthetic genetics, although the basis for DNA site selection is poorly understood. Here we show that attP selection is determined through multiple...

The Indian origin of paternal haplogroup R1a1* substantiates the autochthonous origin of Brahmins and the caste system

Shweta Singh Katayoon Darvishi Audesh K Bhat AJS Bhanwer Pramod Kumar Tiwari Rameshwar NK Bamezai It has come to our attention that the data in the Table 1 of the above article contained incorrect numbers

GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1–2 September 2014

V. Gurevich, Daniel Fourmy, Vadim Cherezov, Fiona H. Marshall, R. Ian Storer, Isabel Moraes, Irina G. Tikhonova, Christofer S. Tautermann, Peter Hunt, Tom Ceska, Simon Hodgson, Mike J. Bodkin, Shweta ... Singh, Richard J. Law and Philip C 5 I. G. Tikhonova Molecular Therapeutics, School of Pharmacy, Medical Biology Centre, Queen's University Belfast , 97 Lisburn Road, Belfast BT9 7BL, Northern Ireland

Recent advances in the molecular basis of Lafora's progressive myoclonus epilepsy

Lafora's disease (LD) is an autosomal recessive and fatal form of progressive myoclonus epilepsy with onset in late childhood or adolescence. LD is characterised by the presence of intracellular polyglucosan inclusions, called Lafora bodies, in tissues including the brain, liver and skin. Patients have progressive neurologic deterioration, leading to death within 10 years of...

Large-scale functional expression of WT and truncated human adenosine A2A receptor in Pichia pastoris bioreactor cultures

Background The large-scale production of G-protein coupled receptors (GPCRs) for functional and structural studies remains a challenge. Recent successes have been made in the expression of a range of GPCRs using Pichia pastoris as an expression host. P. pastoris has a number of advantages over other expression systems including ability to post-translationally modify expressed...