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83 papers found.
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Effect of stem cell transplantation on patients with ischemic heart failure: a systematic review and meta-analysis of randomized controlled trials

Stem cell transplantation (SCT) has become a promising way to treat ischemic heart failure (IHF). We performed a large-scale meta-analysis of randomized clinical trials to investigate the efficacy and safety of SCT in IHF patients. Randomized controlled trials (RCTs) involving stem cell transplantation for the treatment of IHF were identified by searching the PubMed, EMBASE...

Peak urea level, leukocyte count and use of invasive ventilation as risk factors of mortality in acute pancreatitis: A retrospective study

-Nan Liu, Si Chen. Funding acquisition: Jing Zhou. Investigation: Chao-Nan Liu, Si Chen, Hao Chen, Chang-Wei Chen. Software: Chao-Nan Liu, Si Chen. 1. Beckingham IJ , Bornman PC . ABC of diseases of

Neuroprotective Role of Selected Antioxidant Agents in Preventing Cisplatin-Induced Damage of Human Neurons In Vitro

Chemotherapy-induced peripheral neuropathy (CIPN) is a side effect of platinum-based chemotherapy and decreases the quality of life of cancer patients. We compared neuroprotective properties of several agents using an in vitro model of terminally differentiated human cells NT2-N derived from cell line NT2/D1. Sodium azide and an active metabolite of amifostine (WR1065) increase...

DEPTOR regulates osteogenic differentiation via inhibiting MEG3-mediated activation of BMP4 signaling and is involved in osteoporosis

BackgroundThe mammalian target of rapamycin (mTOR) pathway plays a significant role in osteogenic differentiation and bone maintenance. As the only known endogenous inhibitor of mTOR function, DEP domain containing mTOR interacting protein (DEPTOR) is potentially involved in stem cell differentiation, although the pathophysiological significance and its molecular mechanisms...

Research on Human-Error Factors of Civil Aircraft Pilots Based On Grey Relational Analysis

In consideration of the situation that civil aviation accidents involve many human-error factors and show the features of typical grey systems, an index system of civil aviation accident human-error factors is built using human factor analysis and classification system model. With the data of accidents happened worldwide between 2008 and 2011, the correlation between human-error...

VEGFR1 promotes cell migration and proliferation through PLCγ and PI3K pathways

Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USAJared C. Weddell, Si Chen & P. I. Imoukhuede AuthorsSearch for Jared C. Weddell in:Nature Research journals • PubMed • Google ... Scholar Search for Si Chen in:Nature Research journals • PubMed • Google Scholar Search for P. I. Imoukhuede in:Nature Research journals • PubMed • Google Scholar Contributions J.C.W. and P.I.I. designed

A Novel Intensive Distribution Logistics Network Design and Profit Allocation Problem considering Sharing Economy

The rapid growth of logistics distribution highlights the problems including the imperfect infrastructure of logistics distribution network, the serious shortage of distribution capacity of each individual enterprise, and the high cost of distribution in China. While the development of sharing economy makes it possible to achieve the integration of whole social logistic resources...

Genome-wide screen reveals important roles for ESCRT proteins in drug/ion resistance of fission yeast

: Takayoshi Kuno, Yue Fang, Fan Yao. Data curation: Yikun Yang, Qiannan Liu, Guanglie Jiang, Si Chen, Lina Zhou. Formal analysis: Yikun Yang, Qiannan Liu, Guanglie Jiang, Si Chen, Lina Zhou, Norihiro Sakamoto ... . Funding acquisition: Lina Zhou, Yue Fang, Fan Yao. Investigation: Yikun Yang, Qiannan Liu, Guanglie Jiang, Si Chen, Lina Zhou. Methodology: Takayoshi Kuno, Yue Fang, Fan Yao. Project administration

Effects of stimulus duration and vowel quality in cross-linguistic categorical perception of pitch directions

We investigated categorical perception of rising and falling pitch contours by tonal and non-tonal listeners. Specifically, we determined minimum durations needed to perceive both contours and compared to those of production, how stimuli duration affects their perception, whether there is an intrinsic F0 effect, and how first language background, duration, directions of pitch and...

Race and virulence characterization of Puccinia graminis f. sp. tritici in China

. Investigation: Tian Ya Li, Xian Xin Wu, Si Chen, Xiao Feng Xu, Hao Wang, Yuan Yin Cao. Project administration: Tian Ya Li. Resources: Si Chen. Supervision: Yuan Yin Cao. Writing ? original draft: Tian Ya Li

Tissue expression profiles and transcriptional regulation of elongase of very long chain fatty acid 6 in bovine mammary epithelial cells

dual-luciferase reporter plasmids used in this work. (DOC) S3 Table. Site-directed deletion mutation primers used in this work. (DOC) Acknowledgments Si Chen and Xiaolin Liu conceived the experiments ... . Si Chen conducted the experiments and analyzed the results. Xiaolin Liu and Hua He contributed reagents and materials. The manuscript was written by Si Chen. All authors reviewed the manuscript. In

Visualizing Micro-anatomical Structures of the Posterior Cornea with Micro-optical Coherence Tomography

Research Council Singapore (NMRC/CBRG/0036/2013) and NTU-AIT-MUV program in advanced biomedical imaging (NAM/15005). Author information Author notes Si Chen and Xinyu Liu contributed equally to this work ... Chen & Linbo LiuSchool of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459, SingaporeLinbo Liu AuthorsSearch for Si Chen in:Nature Research journals • PubMed

Social Optimization and Pricing Policy in Cognitive Radio Networks with an Energy Saving Strategy

The rapid growth of wireless application results in an increase in demand for spectrum resource and communication energy. In this paper, we firstly introduce a novel energy saving strategy in cognitive radio networks (CRNs) and then propose an appropriate pricing policy for secondary user (SU) packets. We analyze the behavior of data packets in a discrete-time single-server...

Volatile Fatty Acids Production from Codigestion of Food Waste and Sewage Sludge Based on β-Cyclodextrins and Alkaline Treatments

Volatile fatty acids (VFAs) are preferred valuable resources, which can be produced from anaerobic digestion process. This study presents a novel technology using β-cyclodextrins (β-CD) pretreatment integrated alkaline method to enhance VFAs production from codigestion of food waste and sewage sludge. Experiment results showed that optimized ratio of food waste to sewage sludge...

Volatile Fatty Acids Production from Codigestion of Food Waste and Sewage Sludge Based on β-Cyclodextrins and Alkaline Treatments

Volatile fatty acids (VFAs) are preferred valuable resources, which can be produced from anaerobic digestion process. This study presents a novel technology using β-cyclodextrins (β-CD) pretreatment integrated alkaline method to enhance VFAs production from codigestion of food waste and sewage sludge. Experiment results showed that optimized ratio of food waste to sewage sludge...

Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1

Diabetic cardiomyopathy (DCM) is associated with a greater risk of mortality in patients with diabetes mellitus. Currently, no specific treatment has been suggested for DCM treatment. This study demonstrated that myricetin (M) attenuated DCM-associated cardiac injury in mice subjected to streptozotocin (SZT) and in neonatal rat cardiomyocytes (NRCM) challenged with high glucose...

Population pharmacokinetic analysis of tacrolimus in Chinese myasthenia gravis patients

Ping MA and Wei LU designed the research; Ping MA, Zi-qi LIU, and Ling HUANG collected the data and performed the measurements; Yu-si CHEN, Rong CHEN, Xiao ZHU, and Zi-qi LIU graphically explored the ... data and conducted the PopPK analysis; Yu-si CHEN drafted the manuscript; Ping MA, Wei LU, Rong CHEN, and Yu-si CHEN revised the manuscript; Lei WANG provided clinical consultations; Tian-yan ZHOU

A demodulation method of Temperature-Spectrum width based on Chirped fiber grating

Based on spectral reflection characteristics of chirped FBGs, a demodulation method for complex temperature fields is proposed in this paper. Relationships between the reflective spectrums and the temperatures are investigated through theoretical analyses. Testing results are acquired from a FBG sensing model which is designed according to the newly-developed method. A simulation...

Forward and reverse mutations in stages of cancer development

Massive occurrences of interstitial loss of heterozygosity (LOH) likely resulting from gene conversions were found by us in different cancers as a type of single-nucleotide variations (SNVs), comparable in abundance to the commonly investigated gain of heterozygosity (GOH) type of SNVs, raising the question of the relationships between these two opposing types of cancer mutations...

Mid- to long-term outcome comparison of the Medtronic Hancock II and bi-leaflet mechanical aortic valve replacement in patients younger than 60 years of age: a propensity-matched analysis

OBJECTIVE This study aims to compare mid-long-term clinical outcomes between patients younger than 60 years of age undergoing bioprosthetic and mechanical aortic valve replacement.