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Mitofusin-2 is required for mouse oocyte meiotic maturation

• PubMed • Google ScholarSearch for Si-Hua Gao in:Nature Research journals • PubMed • Google ScholarSearch for Ke Wang in:Nature Research journals • PubMed • Google ScholarSearch for Xiu-Yan Yang in:Nature

Curcumin and Diabetes: A Systematic Review

Turmeric (Curcuma longa), a rhizomatous herbaceous perennial plant of the ginger family, has been used for the treatment of diabetes in Ayurvedic and traditional Chinese medicine. The active component of turmeric, curcumin, has caught attention as a potential treatment for diabetes and its complications primarily because it is a relatively safe and inexpensive drug that reduces...

Differential Expression of Long Noncoding RNAs between Sperm Samples from Diabetic and Non-Diabetic Mice

To investigate the potential core reproduction-related genes associated with the development of diabetes, the expression profiles of long noncoding RNA (lncRNA) and messenger RNA (mRNA) in the sperm of diabetic mice were studied. We used microarray analysis to detect the expression of lncRNAs and coding transcripts in six diabetic and six normal sperm samples, and differentially...

Jiang Tang Xiao Ke Granule, a Classic Chinese Herbal Formula, Improves the Effect of Metformin on Lipid and Glucose Metabolism in Diabetic Mice

In the present study, the hypoglycemic, hypolipidemic, and antioxidative effects of metformin (MET) combined with Jiang Tang Xiao Ke (JTXK) granule derived from the “Di Huang Tang” were evaluated in mice with type 2 diabetes mellitus (DM) induced by high-fat diet/streptozotocin. DM mice were orally treated with MET (0.19 g/kg) either alone or combined with different doses (1.75...

Jiang Tang Xiao Ke Granule, a Classic Chinese Herbal Formula, Improves the Effect of Metformin on Lipid and Glucose Metabolism in Diabetic Mice

In the present study, the hypoglycemic, hypolipidemic, and antioxidative effects of metformin (MET) combined with Jiang Tang Xiao Ke (JTXK) granule derived from the “Di Huang Tang” were evaluated in mice with type 2 diabetes mellitus (DM) induced by high-fat diet/streptozotocin. DM mice were orally treated with MET (0.19 g/kg) either alone or combined with different doses (1.75...

Effects of Postmortem Interval on Mouse Ovary Oocyte Survival and Maturation

To study the time- and temperature-dependent survival of ovarian oocytes collected from postmortem carcass, ICR mice were killed and placed for different periods (0, 1, 2, 4, 6, 8 and 10 h) at different temperatures (25°C, 4°C and 37°C). After preservation, oocyte morphology, germinal vesicle (GV) oocyte number, oocyte meiotic maturation percentage, mitochondrial distribution and...

Lung and Intestine: A Specific Link in an Ulcerative Colitis Rat Model

present study provided a new way of thinking for pathological changes in clinical complex diseases manifested with multiorgan damage. Author’s Contribution Xin-Yue Wang and Si-Hua Gao designed the research

Antidiabetic and Antioxidative Effect of Jiang Tang Xiao Ke Granule in High-Fat Diet and Low-Dose Streptozotocin Induced Diabetic Rats

diabetes [14]. Jiang Tang Xiao Ke (JTXK) granule is a specific formula created by Professor Si-Hua Gao based on his experience in the clinical management of DM. It has been used clinically for several years

Antidiabetic and Antioxidative Effect of Jiang Tang Xiao Ke Granule in High-Fat Diet and Low-Dose Streptozotocin Induced Diabetic Rats

diabetes [14]. Jiang Tang Xiao Ke (JTXK) granule is a specific formula created by Professor Si-Hua Gao based on his experience in the clinical management of DM. It has been used clinically for several years

Historical Perspective of Traditional Indigenous Medical Practices: The Current Renaissance and Conservation of Herbal Resources

’ Contribution Si-Yuan Pan, Gerhard Litscher, Si-Hua Gao, Shu-Feng Zhou, and Zhi-Ling Yu equally contributed to this work. Acknowledgments This paper was supported by the National Natural Science Foundation of

Historical Perspective of Traditional Indigenous Medical Practices: The Current Renaissance and Conservation of Herbal Resources

’ Contribution Si-Yuan Pan, Gerhard Litscher, Si-Hua Gao, Shu-Feng Zhou, and Zhi-Ling Yu equally contributed to this work. Acknowledgments This paper was supported by the National Natural Science Foundation of

Clinical Trial on the Characteristics of Zheng Classification of Pulmonary Diseases Based on Infrared Thermal Imaging Technology

Zheng classification study based on infrared thermal imaging technology has not been reported before. To detect the relative temperature of viscera and bowels of different syndromes patients with pulmonary disease and to summarize the characteristics of different Zheng classifications, the infrared thermal imaging technology was used in the clinical trial. The results showed that...

Specific Link between Lung and Large Intestine: A New Perspective on Neuropeptide Secretion in Lung with Herbal Laxative Stimulation

, Yu-Chao Liu, Miao Liu, Ruo-Han Wu, Yu-Shan Gao, Shu-Jing Zhang, Jin-Chao Zhang, Tian-Yu Zhang, and Si-Hua Gao School of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing 100029 ... ]. Conflict of Interests The authors declare that they have no conflict of interests. Authors’ Contributions Xiang-Gen Zhong and Feng-Jie Zheng have equally contributed to this paper. Yu-Hang Li and Si-Hua Gao

New Perspectives on How to Discover Drugs from Herbal Medicines: CAM's Outstanding Contribution to Modern Therapeutics

With tens of thousands of plant species on earth, we are endowed with an enormous wealth of medicinal remedies from Mother Nature. Natural products and their derivatives represent more than 50% of all the drugs in modern therapeutics. Because of the low success rate and huge capital investment need, the research and development of conventional drugs are very costly and difficult...

New Perspectives on How to Discover Drugs from Herbal Medicines: CAM's Outstanding Contribution to Modern Therapeutics

With tens of thousands of plant species on earth, we are endowed with an enormous wealth of medicinal remedies from Mother Nature. Natural products and their derivatives represent more than 50% of all the drugs in modern therapeutics. Because of the low success rate and huge capital investment need, the research and development of conventional drugs are very costly and difficult...