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Deficiency of the Purinergic Receptor 2X7 Attenuates Nonalcoholic Steatohepatitis Induced by High-Fat Diet: Possible Role of the NLRP3 Inflammasome

Blasetti Fantauzzi, Stefano Menini, Anna Solini, and Giuseppe Pugliese conceived the project and designed the experiments. Claudia Blasetti Fantauzzi, Carla Iacobini, Chiara Rossi, and Eleonora Santini ... performed molecular analyses (Western blot and qRT-PCR). Stefano Menini performed morphological/morphometric analyses and IHC. Giuseppe Pugliese performed biochemical analyses and ELISA. Claudia Blasetti

Deficiency of the Purinergic Receptor 2X7 Attenuates Nonalcoholic Steatohepatitis Induced by High-Fat Diet: Possible Role of the NLRP3 Inflammasome

Blasetti Fantauzzi, Stefano Menini, Anna Solini, and Giuseppe Pugliese conceived the project and designed the experiments. Claudia Blasetti Fantauzzi, Carla Iacobini, Chiara Rossi, and Eleonora Santini ... performed molecular analyses (Western blot and qRT-PCR). Stefano Menini performed morphological/morphometric analyses and IHC. Giuseppe Pugliese performed biochemical analyses and ELISA. Claudia Blasetti

Correlates of Calcaneal Quantitative Ultrasound Parameters in Patients with Diabetes: The Study on the Assessment of Determinants of Muscle and Bone Strength Abnormalities in Diabetes

,1,2 Stefano Balducci,1,2,3 Luca Pugliese,4 Valeria D’Errico,1,2,3 Martina Vitale,1,2 Elena Alessi,1,2 Gerardo Salerno,1,5 Carla Iacobini,1 Stefano Menini,1 Lucilla Bollanti,1,2 Antonio Nicolucci,6 and ... , Stefano Menini, Lucilla Bollanti, and Antonio Nicolucci critically revised the article for important intellectual content. All authors agreed to be accountable for all aspects of the work and approved

Correlates of Calcaneal Quantitative Ultrasound Parameters in Patients with Diabetes: The Study on the Assessment of Determinants of Muscle and Bone Strength Abnormalities in Diabetes

,1,2 Stefano Balducci,1,2,3 Luca Pugliese,4 Valeria D’Errico,1,2,3 Martina Vitale,1,2 Elena Alessi,1,2 Gerardo Salerno,1,5 Carla Iacobini,1 Stefano Menini,1 Lucilla Bollanti,1,2 Antonio Nicolucci,6 and ... , Stefano Menini, Lucilla Bollanti, and Antonio Nicolucci critically revised the article for important intellectual content. All authors agreed to be accountable for all aspects of the work and approved

Role of Galectin-3 in Obesity and Impaired Glucose Homeostasis

; Accepted 31 August 2015 Academic Editor: Umesh Yadav Copyright © 2016 Stefano Menini et al. This is an open access article distributed under the Creative Commons Attribution License, which permits

Role of Galectin-3 in Obesity and Impaired Glucose Homeostasis

; Accepted 31 August 2015 Academic Editor: Umesh Yadav Copyright © 2016 Stefano Menini et al. This is an open access article distributed under the Creative Commons Attribution License, which permits

Protection from diabetes-induced atherosclerosis and renal disease by d-carnosine-octylester: effects of early vs late inhibition of advanced glycation end-products in Apoe-null mice

Stefano Menini Carla Iacobini Carlo Ricci Claudia Blasetti Fantauzzi Giuseppe Pugliese Abbreviations BCA CML DCCT/EDIC 0 Department of Clinical and Molecular Medicine, 'La Sapienza' University , Via di ... -products; AGE; Atherosclerosis; Carnosine; Reactive carbonyl species; Renal disease - Stefano Menini and Carla Iacobini contributed equally to this work. Brachiocephalic artery Nε-Carboxymethyllysine

CYCLOOXYGENASE 2 EXPRESSION IN VESSELS AND NERVES IN REVERSAL REACTION LEPROSY

Pesce, Myriam Grattarola, and Stefano Menini, DISTBIMO, University of Genoa Medical School, Largo Benzi 10, Pad. IV, 16132 Genova, Italy, E-mails: , , and ; Paolo Fiallo, Sezione di Dermatologia Sociale

TIMP3 Overexpression in Macrophages Protects From Insulin Resistance, Adipose Inflammation, and Nonalcoholic Fatty Liver Disease in Mice

Rossella Menghini Viviana Casagrande Stefano Menini Arianna Marino Valeria Marzano Marta L. Hribal Paolo Gentileschi Davide Lauro Orazio Schillaci Giuseppe Pugliese Paolo Sbraccia Andrea Urbani

Role of TGF-β/GLUT1 axis in susceptibility vs resistance to diabetic glomerulopathy in the Milan rat model

Background. GLUT1 upregulation and increased glucose transport activity may contribute to extracellullar matrix (ECM) accumulation characterizing diabetic nephropathy (DN). Rats of the Milan hypertensive strain (MHS) are resistant to both hypertensive and diabetic renal disease, due to a haemodynamic protection. On the contrary, those of the Milan normotensive strain (MNS...

Deletion of p66Shc Longevity Gene Protects Against Experimental Diabetic Glomerulopathy by Preventing Diabetes-Induced Oxidative Stress

p66Shc regulates both steady-state and environmental stress-dependent reactive oxygen species (ROS) generation. Its deletion was shown to confer resistance to oxidative stress and protect mice from aging-associated vascular disease. This study was aimed at verifying the hypothesis that p66Shc deletion also protects from diabetic glomerulopathy by reducing oxidative stress...

Evaluation of Polyneuropathy Markers in Type 1 Diabetic Kidney Transplant Patients and Effects of Islet Transplantation: Neurophysiological and skin biopsy longitudinal analysis

UBALDO DEL CARRO PAOLO FIORINA PHD STEFANO AMADIO LUISA DE TONI FRANCESCHINI ALESSANDRA PETRELLI STEFANO MENINI PHD OBJECTIVE - The purpose of this study was to evaluate whether islet

Comparative Trial of N-Acetyl-Cysteine, Taurine, and Oxerutin on Skin and Kidney Damage in Long-Term Experimental Diabetes

This study analyzes the effect of chronic treatment with different antioxidants (N-acetyl-cysteine [NAC], taurine, a combination of NAC and taurine, and oxerutin) on long-term experimental diabetes induced by streptozotocin in rats. Glycoxidative damage was evaluated in the skin; glomerular structural changes were studied with morphometry and immunohistochemistry. Oxerutin...