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Search: authors:"Stephan Braun"

6 papers found.
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Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report

Introduction Well-documented cases of untreated cervical intra-epithelial dysplasia resulting in fatal progression of invasive cervical cancer are scarce because of a long pre-invasive state, the availability of cervical cytology screening programs, and the efficacy of the treatment of both pre-invasive and early-stage invasive lesions. Case presentation We present a well...

Recent advances in technologies for the detection of occult metastatic cells in bone marrow of breast cancer patients

Approximately half of breast cancer patients with stage I–III disease will suffer metastatic disease despite resection with tumour-free margins. In 30–40% of these patients, individual carcinoma cells can already be detected at the time of primary therapy in cytological bone marrow preparations using immunocytochemistry. Numerous prospective clinical studies have shown that the...

Design of new benzoxazole-2-thione-derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole

The bacterial hyaluronan lyases (Hyals) that degrade hyaluronan, an important component of the extracellular matrix, are involved in microbial spread. Inhibitors of these enzymes are essential in investigation of the role of hyaluronan and Hyal in bacterial infections and constitute a new class of antibiotics against Hyal-producing bacteria. Recently, we identified 1,3...

Re: Micrometastatic Breast Cancer Cells in Bone Marrow at Primary Surgery: Prognostic Value in Comparison With Nodal Status

appropriate, since occult metastatic cells may disclose their influence on survival at 10 years or later. STEPHAN BRAUN MANFRED MU LLER FLORIAN HEPP GU NTER SCHLIMOK GERT RIETHMU LLER KLAUS PANTEL ficity of

Poster discussions

Introduction The purpose of the present study was to examine the prevalence of sexual dysfunction in newly diagnosed sexually active colorectal cancer female patients prior to treatment and identify the characteristics and correlates of dysfunction.