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Gut microbiota and butyrate level changes associated with the long-term administration of proton pump inhibitors to old rats

The association between adverse effects of PPI and gut microbiota in old age has yet to be elucidated. We assessed changes in the gut microbiota and butyrate levels following the long-term administration of PPIs to old rats and investigated their associations. F344 aged male rats were fed a PPI-supplemented diet for 50 weeks. The ileal microbiota was analysed by metagenomic...

Prevalence and risk factors of latent tuberculosis among Korean healthcare workers using whole-blood interferon-γ release assay

Because healthcare workers (HCWs) are at high risk for tuberculosis (TB) infection, it is essential to research the prevalence of latent TB infection (LTBI) and to implement health interventions including early treatment of LTBI and TB infection control measures. The purpose of the study was to determine the prevalence and risk factors for LTBI using interferon-γ release assay...

Probiotics reduce repeated water avoidance stress-induced colonic microinflammation in Wistar rats in a sex-specific manner

: Nayoung Kim, Hyuk Yoon. Data curation: Ju Yup Lee. Formal analysis: Ju Yup Lee. Funding acquisition: Nayoung Kim. Investigation: Ryoung Hee Nam, Sung Hwa Sohn, Sun Min Lee, Daeun Choi, Hye Seung Lee

Changes in the interstitial cells of Cajal and neuronal nitric oxide synthase positive neuronal cells with aging in the esophagus of F344 rats

peristalsis and LES relaxation. Author Contributions Conceptualization: Nayoung Kim. Data curation: Ryoung Hee Nam, Sun Min Lee, Ji Hyun Park, Daeun Choi. Formal analysis: Hee Jin Kim, Ryoung Hee Nam, Sun ... Lee. Supervision: Nayoung Kim. Visualization: Ryoung Hee Nam, Sun Min Lee, Ji Hyun Park, Daeun Choi, Min-Seob Kim, Moon Young Lee. Writing ? original draft: Hee Jin Kim. Writing ? review & editing

Change in the Interstitial Cells of Cajal and nNOS Positive Neuronal Cells with Aging in the Stomach of F344 Rats

The gastric accommodation reflex is an important mechanism in gastric physiology. However, the aging-associated structural and functional changes in gastric relaxation have not yet been established. Thus, we evaluated the molecular changes of interstitial cell of Cajal (ICC) and neuronal nitric oxide synthase (nNOS) and the function changes in the corpus of F344 rats at different...

Urinary Malondialdehyde Is Associated with Visceral Abdominal Obesity in Middle-Aged Men

; Accepted 25 August 2015 Academic Editor: Doan T. M. Ngo Copyright © 2015 Sun Min Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits

Urinary Malondialdehyde Is Associated with Visceral Abdominal Obesity in Middle-Aged Men

; Accepted 25 August 2015 Academic Editor: Doan T. M. Ngo Copyright © 2015 Sun Min Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits