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Age- and gender-specific reference intervals of TSH and free T4 in an iodine-replete area: Data from Korean National Health and Nutrition Examination Survey IV (2013–2015)

Contributions Conceptualization: So Young Park, Hae In Kim, Jae Hoon Chung, Myung-Hee Shin, Sun Wook Kim. Data curation: So Young Park, Hae In Kim, Hye Won Jang, Myung-Hee Shin, Sun Wook Kim. Formal analysis ... : Jae Hoon Chung, Sun Wook Kim. Validation: Myung-Hee Shin, Sun Wook Kim. 10 / 12 Writing ? original draft: So Young Park, Tae Hyuk Kim, Sun Wook Kim. Writing ? review & editing: So Young Park, Tae Hyuk

Association between Frailty and Hypertension Prevalence, Treatment, and Control in the Elderly Korean Population

Frailty is a common geriatric syndrome characterized by increased risk of disability, hospitalization, and mortality. Hypertension (HTN) is one of the most common chronic medical conditions in the elderly. However, there have been few studies regarding the association between frailty and HTN prevalence, treatment, and control rates. We analyzed data of 4,352 older adults (age...

Preoperative serum thyroglobulin predicts initial distant metastasis in patients with differentiated thyroid cancer

Sun Wook Kim in:Nature Research journals • PubMed • Google Scholar Contributions All authors contributed to the design of the study and writing of the manuscript. Conceptualization, T.H.K., S.W.K. and ... competing interests. Corresponding authors Correspondence to Tae Hyuk Kim or Sun Wook Kim. Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0

Prediction of Mortality and Postoperative Complications using the Hip-Multidimensional Frailty Score in Elderly Patients with Hip Fracture

High mortality and dependent living after hip fracture pose a significant public health concern. Retrospective study was conducted with 481 hip fracture patients (≥65 years of age) undergoing surgery from March 2009 to May 2014. The Hip-MFS was calculated by Comprehensive Geriatric Assessment (CGA). The primary outcome was the 6-month all-cause mortality rate. The secondary...

A New Equation to Estimate Muscle Mass from Creatinine and Cystatin C

Background With evaluation for physical performance, measuring muscle mass is an important step in detecting sarcopenia. However, there are no methods to estimate muscle mass from blood sampling. Methods To develop a new equation to estimate total-body muscle mass with serum creatinine and cystatin C level, we designed a cross-sectional study with separate derivation and...

Subclinical thyroid dysfunction and risk of carotid atherosclerosis

Contributions Conceptualization: Tae Hyuk Kim, Mira Kang, Sun Wook Kim. Data curation: Tae Hyuk Kim. Formal analysis: Hosu Kim. Funding acquisition: Sun Wook Kim. Investigation: Hye In Kim, So Young Park ... Min, Jae Hoon Chung, Sun Wook Kim. Visualization: Min-Ji Kim. 9 / 11 Writing ± original draft: Hosu Kim, Tae Hyuk Kim. Writing ± review & editing: Hosu Kim, Seonwoo Kim, Mira Kang, Sun Wook Kim. 10

Effect of Rifampin on Thyroid Function Test in Patients on Levothyroxine Medication

Background Levothyroxine (LT4) and rifampin (RIF) are sometimes used together; however, no clinical studies have assessed the effects of these drugs on thyroid function or the need to adjust LT4 dose. Methods We retrospectively reviewed the records of 71 Korean patients who started RIF during LT4 treatment. Clinically relevant cases that required dose adjustment according to the...

Frailty as a Predictor of Acute Kidney Injury in Hospitalized Elderly Patients: A Single Center, Retrospective Cohort Study

Background Elderly patients have an increased risk for acute kidney injury (AKI). However, few studies have reported on predictors for AKI in geriatric patients. Therefore, we aimed at determining the effect of frailty as a predictor of AKI. Methods We retrospectively enrolled 533 hospitalized elderly patients (aged ≥ 65 years) who had their creatinine levels measured (≥ 1...

Insulin Resistance Is Associated with Prevalence of Physician-Diagnosed Urinary Incontinence in Postmenopausal Non-Diabetic Adult Women: Data from the Fourth Korea National Health and Nutrition Examination Survey

Objective To investigate the association between insulin resistance (IR) and urinary incontinence in Korean adult women by analyzing the data from the Korea National Health and Nutrition Examination Survey IV (KNHANES) 2007–2009 Methods A nationally representative sample of 5318 non-diabetic Korean women ≥19-years-of-age (3043 premenopausal and 2275 postmenopausal women) was...

A Modest Protective Effect of Thyrotropin against Bone Loss Is Associated with Plasma Triiodothyronine Levels

Background The independent skeletal effect of thyrotropin (thyroid stimulating hormone, TSH) has been suggested in animal studies. However, clinical data on the association between bone loss and variations in TSH levels is inconsistent. This study aimed to investigate the relationship between TSH levels and bone mineral density (BMD). Methods We conducted a cross-sectional study...

Prevalence and Outcomes of Frailty in Korean Elderly Population: Comparisons of a Multidimensional Frailty Index with Two Phenotype Models

Background Frailty is related to adverse outcomes in the elderly. However, current status and clinical significance of frailty have not been evaluated for the Korean elderly population. We aimed to investigate the usefulness of established frailty criteria for community-dwelling Korean elderly. We also tried to develop and validate a new frailty index based on a multidimensional...