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Search: authors:"Sung Hee Lim"

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The Impacts of Inclusion in Clinical Trials on Outcomes among Patients with Metastatic Breast Cancer (MBC)

Background Metastatic breast cancer (MBC) remains a devastating and incurable disease. Over the past decade, the implementation of clinical trials both with and without molecular targeted therapeutics has impacted the daily clinical treatment of patients with MBC. In this study, we determine whether including MBC patients in clinical trials affects clinical outcomes. Methods We...

Clinicopathological Features and Prognostic Factors Affecting Survival Outcomes in Isolated Locoregional Recurrence of Breast Cancer: Single-Institutional Series

Purpose The purpose of this study was to investigate the clinicopathologic features and prognostic factors affecting outcome in patients with isolated locoregional recurrence of breast cancer (ILRR). Methods We retrospectively analyzed the medical records of 104 patients who were diagnosed with ILRR and underwent curative surgery from January 2000 to December 2010 at Samsung...

Gene Expression Profiling of Breast Cancer Brain Metastasis

Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaJi Yun Lee, Sung Hee Lim, Ji-Yeon Kim, Jin Seok Ahn, Young-Hyuck Im & Yeon Hee ParkSamsung Genomic Institute, Samsung ... ScholarSearch for Sung Hee Lim in:Nature Research journals • PubMed • Google ScholarSearch for Mineui Hong in:Nature Research journals • PubMed • Google ScholarSearch for In-Gu Do in:Nature Research journals

The impact of KRAS mutations on prognosis in surgically resected colorectal cancer patients with liver and lung metastases: a retrospective analysis

Background KRAS mutations are common in colorectal cancer (CRC). The role of KRAS mutation status as a prognostic factor remains controversial, and most large population-based cohorts usually consist of patients with non-metastatic CRC. We evaluated the impact of KRAS mutations on the time to recurrence (TTR) and overall survival (OS) in patients with metastatic CRC who underwent...