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16 papers found.
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Clinical characteristics and 12-month outcomes of patients with valvular and non-valvular atrial fibrillation in Kenya

, Eric J. Velazquez, Jennifer Wessel, Sylvester Kimaiyo, Thomas S. Inui, Gerald S. Bloomfield. Data curation: Loise Ng'ang'a, Gerald S. Bloomfield. Formal analysis: Tecla M. Temu, Kathleen A. Lane ... , Changyu Shen, Loise Ng'ang'a, Thomas S. Inui, Gerald S. Bloomfield. Funding acquisition: Peng-Sheng Chen, Sylvester Kimaiyo, Thomas S. Inui, Gerald S. Bloomfield. Bloomfield. Bloomfield. Inui, Gerald

Nurse Management of Hypertension in Rural Western Kenya: Implementation Research to Optimize Delivery

BackgroundHypertension is the leading global risk factor for mortality. Hypertension treatment and control rates are low worldwide, and insufficient human resource capacity is among the contributing factors. Thus, a critical component of hypertension management is to develop novel and effective solutions to the human resources challenge. One potential solution is task...

Blood pressure level impacts risk of death among HIV seropositive adults in Kenya: a retrospective analysis of electronic health records

Background Mortality among people with human immunodeficiency virus (HIV) infection is increasingly due to non-communicable causes. This has been observed mostly in developed countries and the routine care of HIV infected individuals has now expanded to include attention to cardiovascular risk factors. Cardiovascular risk factors such as high blood pressure are often overlooked...

What Is the Impact of Home-Based HIV Counseling and Testing on the Clinical Status of Newly Enrolled Adults in a Large HIV Care Program in Western Kenya?

(See the Editorial Commentary by Mills and Ford, on pages 282–4.) Background. This article describes the effect point of entry into the human immunodeficiency virus (HIV) care program had on the clinical status of adults presenting for the first time to USAID-AMPATH (US Agency for International Development–Academic Model Providing Access to Healthcare) Partnership clinics for HIV...

Hypertension and Obesity as Cardiovascular Risk Factors among HIV Seropositive Patients in Western Kenya

Kimaiyo 0 Adrian V. Hernandez, Lerner Research Institute, Cleveland Clinic, United States of America 0 1 Division of Cardiology and Duke Clinical Research Institute, Duke University , Durham , North

A clinician-nurse model to reduce early mortality and increase clinic retention among high-risk HIV-infected patients initiating combination antiretroviral treatment

Background In resource-poor settings, mortality is at its highest during the first 3 months after combination antiretroviral treatment (cART) initiation. A clear predictor of mortality during this period is having a low CD4 count at the time of treatment initiation. The objective of this study was to evaluate the effect on survival and clinic retention of a nurse-based rapid...

Alternative antiretroviral monitoring strategies for HIV-infected patients in east Africa: opportunities to save more lives?

Background Updated World Health Organization guidelines have amplified debate about how resource constraints should impact monitoring strategies for HIV-infected persons on combination antiretroviral therapy (cART). We estimated the incremental benefit and cost effectiveness of alternative monitoring strategies for east Africans with known HIV infection. Methods Using a validated...

Feasibility intervention trial of two types of improved cookstoves in three resource-limited settings: study protocol for a randomized controlled trial

Subarna Khatry 2 6 Diana Menya 5 Robert H Gilman 4 6 James M Tielsch 6 Caitlin Kennedy 6 Robert Dreibelbis 6 Neha Naithani 6 Sylvester Kimaiyo 5 Marilu Chiang 4 E Jane Carter 3 Charles B Sherman 3 Patrick N

Short-Term Rationing of Combination Antiretroviral Therapy: Impact on Morbidity, Mortality, and Loss to Follow-Up in a Large HIV Treatment Program in Western Kenya

-Kaloustian,1 Sylvester Kimaiyo,2,3 Hai Liu,1 Adrian Katschke,1 Changyu Shen,1 Gilbert Simiyu,2 Beverly S. Musick,1 John E. Sidle,1,2,3 Abraham Siika,2,3 and Paula Braitstein1,2,3,4,5 1Indiana University

Short-Term Rationing of Combination Antiretroviral Therapy: Impact on Morbidity, Mortality, and Loss to Follow-Up in a Large HIV Treatment Program in Western Kenya

-Kaloustian,1 Sylvester Kimaiyo,2,3 Hai Liu,1 Adrian Katschke,1 Changyu Shen,1 Gilbert Simiyu,2 Beverly S. Musick,1 John E. Sidle,1,2,3 Abraham Siika,2,3 and Paula Braitstein1,2,3,4,5 1Indiana University

Optimizing linkage and retention to hypertension care in rural Kenya (LARK hypertension study): study protocol for a randomized controlled trial

Background Hypertension is the leading global risk factor for mortality. Hypertension treatment and control rates are low worldwide, and delays in seeking care are associated with increased mortality. Thus, a critical component of hypertension management is to optimize linkage and retention to care. Methods/Design This study investigates whether community health workers, equipped...

Prevalence of Potential Drug-Drug Interactions Involving Antiretroviral Drugs in a Large Kenyan Cohort

Background Clinically significant drug-drug interactions (CSDIs) involving antiretrovirals are frequent and under-recognized in developed countries, but data are lacking for developing countries. Methodology and Principal Findings To investigate the prevalence of CSDIs between antiretrovirals and coadministered drugs, we surveyed prescriptions dispensed in a large HIV clinic in...

A model for extending antiretroviral care beyond the rural health centre

Background A major obstacle facing many lower-income countries in establishing and maintaining HIV treatment programmes is the scarcity of trained health care providers. To address this shortage, the World Health Organization has recommend task shifting to HIV-infected peers. Methods We designed a model of HIV care that utilizes HIV-infected patients, community care coordinators...

Sampling-Based Approaches to Improve Estimation of Mortality among Patient Dropouts: Experience from a Large PEPFAR-Funded Program in Western Kenya

Background Monitoring and evaluation (M&E) of HIV care and treatment programs is impacted by losses to follow-up (LTFU) in the patient population. The severity of this effect is undeniable but its extent unknown. Tracing all lost patients addresses this but census methods are not feasible in programs involving rapid scale-up of HIV treatment in the developing world. Sampling...

Nevirapine- Versus Lopinavir/Ritonavir-Based Initial Therapy for HIV-1 Infection among Women in Africa: A Randomized Trial

In a randomized control trial, Shahin Lockman and colleagues compare nevirapine-based therapy with lopinavir/ritonavir-based therapy for HIV-infected women without previous exposure to antiretroviral treatment.