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18 papers found.
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A Simpler Creatinine Index Can Predict Long-Term Survival in Chinese Hemodialysis Patients

Background Low lean body mass (LBM) is an indicator of malnutrition inflammation syndrome, which is common in hemodialysis (HD) patients. The creatinine index (CI) has been validated as a reliable method to estimate LBM and evaluate the protein-energy status of HD patients. However, the traditional creatinine index formula was complex. We sought to investigate the impact of CI...

Ketoanalogues supplementation decreases dialysis and mortality risk in patients with anemic advanced chronic kidney disease

Background The benefit of alpha-Ketoanalogues (KA) supplementation for chronic kidney disease (CKD) patients that followed low-protein diet (LPD) remains undetermined. Methods We extracted longitudinal data for all CKD patients in the Taiwan National Health Insurance from January 1, 2000 through December 31, 2010. A total of 1483 patients with anemic advanced CKD treated with LPD...

Add-on Protective Effect of Pentoxifylline in Advanced Chronic Kidney Disease Treated with Renin-Angiotensin-Aldosterone System Blockade - A Nationwide Database Analysis

TarngDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, TaiwanDer-Cherng Tarng AuthorsSearch for Ko-Lin Kuo in:Nature Research journals • PubMed • Google ScholarSearch for Szu-Chun ... Hung in:Nature Research journals • PubMed • Google ScholarSearch for Jia-Sin Liu in:Nature Research journals • PubMed • Google ScholarSearch for Yu-Kang Chang in:Nature Research journals • PubMed

Iron supplementation associates with low mortality in pre-dialyzed advanced chronic kidney disease patients receiving erythropoiesis-stimulating agents: a nationwide database analysis

Background A risk/benefit analysis of iron supplementation in pre-dialysis advanced chronic kidney disease (CKD) patients has not been conducted. We aim to assess the effectiveness and the safety of iron supplementation in patients with CKD Stage 5 who have not yet received dialysis (CKD 5 ND).

Proteinuria as a Therapeutic Target in Advanced Chronic Kidney Disease: a Retrospective Multicenter Cohort Study

journals • PubMed • Google ScholarSearch for Szu-Chun Hung in:Nature Research journals • PubMed • Google ScholarSearch for Wei-Chih Kan in:Nature Research journals • PubMed • Google ScholarSearch for Chung

Thiazolidinediones and Risk of Long-Term Dialysis in Diabetic Patients with Advanced Chronic Kidney Disease: A Nationwide Cohort Study

Thiazolidinediones (TZDs) reduce urinary albumin excretion and proteinuria in diabetic nephropathy. The effect of TZDs on hard renal outcome in diabetic patients with chronic kidney disease (CKD) is unknown. We investigate the association of TZDs and risk of long-term dialysis or death in diabetic patients with advanced CKD. The nationwide population-based cohort study was...

Progression of Kidney Disease in Non-Diabetic Patients with Coronary Artery Disease: Predictive Role of Circulating Matrix Metalloproteinase-2, -3, and -9

Background Circulating matrix metalloproteinase (MMP)-2, -3 and -9 are well recognized in predicting cardiovascular outcome in coronary artery disease (CAD), but their risks for chronic kidney disease (CKD) are lacking. Therefore, the present study aimed to investigate whether circulating MMP levels could independently predict future kidney disease progression in non-diabetic CAD...

Intravenous Ferric Chloride Hexahydrate Supplementation Induced Endothelial Dysfunction and Increased Cardiovascular Risk among Hemodialysis Patients

Background The association between intravenous (IV) iron administration and outcomes in hemodialysis (HD) patients is still debated. Therefore, this study was aimed to assess the relationship between the IV administration of ferric chloride hexahydrate (Atofen®) and cardiovascular (CV) outcome and the interaction between iron-induced oxidative stress and endothelial dysfunction...

Comparison of 24-h Urinary Aldosterone Level and Random Urinary Aldosterone-to-Creatinine Ratio in the Diagnosis of Primary Aldosteronism

Background Historically, urinary aldosterone level measurement was a commonly employed confirmatory test to detect primary aldosteronism (PA). However, 24-h urine collection is inconvenient and cumbersome. We hypothesized that random urinary aldosterone measurements with correction for creatinine concentration might be comparable to 24-h urinary aldosterone levels (Uald-24 h) in...

Painful haematuria following central venous catheter infection

Nephroquiz (Section Editor: M. G. Zeier) 0 Case 0 0 Cheng-Hung Huang Szu-Chun Hung Sze-Hung Hung Division of Nephrology Department of Medicine Taipei Veterans General Hospital and National Yang-Ming

Dialysis‐resistant pulmonary oedema

Nephroquiz (Section Editor: M. G. Zeier) 0 Case 0 0 Szu-Chun Hung Sze-Hung Hung Wu-Chang Yang Der-Cherng Tarng Division of Nephrology Department of Medicine Taipei Veterans General Hospital and

Anaemia in CKD 1-5

Introduction and Aims: C.E.R.A. is a long-acting erythropoiesis stimulating agent widely used to treat anemia in patients with chronic kidney disease. Although C.E.R.A. shows clinical benefits with respect to kidney disease in diabetic nephropathy models, the therapeutic effects on the progression of kidney disease have not been fully elucidated. In this study we aimed to...


Introduction and Aims: Uric acid (UA) has been identified as a prognostic marker of chronic kidney disease (CKD) progression. Preclinical studies also support an independent pathophysiological role of UA in this process. Treatment of hyperuricemia in CKD can be challenging as it requires dose reduction of the most frequently used urate lowering therapy (ULT), the xanthineoxidase...

Clinical Nephrology - Epidemiology II

Introduction and Aims: The Birmingham Vasculitis Activity Score (BVAS) correlates closely with disease activity in patients with ANCA associated vasculitis, however, conflicting results have been reported about its association with mortality. In this retrospective cohort study we assessed if BVAS at the time of diagnosis predicts mortality in a group of consecutive patients with...