Advanced search    

Search: authors:"Tae Min Kim"

37 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Renal Ischemia-Reperfusion Injury in a Diabetic Monkey Model and Therapeutic Testing of Human Bone Marrow-Derived Mesenchymal Stem Cells

declare that they have no conflicts of interests. Authors? Contributions Kyo Won Lee and Tae Min Kim contributed equally to this work. Acknowledgments The authors thank the Laboratory Animal Research

Intratumoral heterogeneity characterized by pretreatment PET in non-small cell lung cancer patients predicts progression-free survival on EGFR tyrosine kinase inhibitor

, Seunggyun Ha, Se-Hoon Lee, Bhumsuk Keam, Tae Min Kim. Formal analysis: Sehhoon Park, Seunggyun Ha, Se-Hoon Lee, Jin Chul Paeng, Bhumsuk Keam. Funding acquisition: Se-Hoon Lee. Investigation: Se-Hoon Lee ... , Jin Chul Paeng. Methodology: Sehhoon Park, Seunggyun Ha, Se-Hoon Lee, Jin Chul Paeng, Bhumsuk Keam, Tae Min Kim, Dong-Wan Kim, Dae Seog Heo. Project administration: Se-Hoon Lee. Resources: Seunggyun

A molecular portrait of microsatellite instability across multiple cancers

Research journals • PubMed • Google ScholarSearch for Tae-Min Kim in:Nature Research journals • PubMed • Google ScholarSearch for Peter J. Park in:Nature Research journals • PubMed • Google Scholar ... I.C.-C. and P.J.P. with substantial input from T.-M.K. and S.L. Competing interests The authors declare no competing financial interests. Corresponding authors Correspondence to Tae-Min Kim or Peter J

Therapeutic effects of anti-CD154 antibody in cynomolgus monkeys with advanced rheumatoid arthritis

JehoonYang Yeongbeen Kwon Tae Min Kim Jae Berm Park Sungjoo Kim OPEN Rheumatoid arthritis is one major chronic inflammatory systemic autoimmune disease. The CD154-CD40 interactions play a critical role in the

The prognostic value of CT radiomic features for patients with pulmonary adenocarcinoma treated with EGFR tyrosine kinase inhibitors

Kim, Dong-Wan Kim, Dae Seog Heo, Jin Mo Goo. Methodology: Hyungjin Kim, Chang Min Park, Bhumsuk Keam, Sang Joon Park, Miso Kim, Tae Min Kim, Dong-Wan Kim, Dae Seog Heo, Jin Mo Goo. Project ... administration: Hyungjin Kim, Chang Min Park, Bhumsuk Keam. Resources: Chang Min Park, Bhumsuk Keam, Sang Joon Park, Miso Kim, Tae Min Kim, Dong-Wan Kim, Dae Seog Heo, Jin Mo Goo. Software: Sang Joon Park

Copy number analysis of whole-genome data using BIC-seq2 and its application to detection of cancer susceptibility variants

Whole-genome sequencing data allow detection of copy number variation (CNV) at high resolution. However, estimation based on read coverage along the genome suffers from bias due to GC content and other factors. Here, we develop an algorithm called BIC-seq2 that combines normalization of the data at the nucleotide level and Bayesian information criterion-based segmentation to...

Leakage correction improves prognosis prediction of dynamic susceptibility contrast perfusion MRI in primary central nervous system lymphoma

-EulYoo Koung Mi Kang Tae JinYun Ji-hoon Chul-Ho Sohn Sung-Hye Park Jae-Kyung Won Tae Min Kim Chul-Kee Park Il Han Kim OPEN Published: xx xx xxxx To evaluate whether the cerebral blood volume (CBV

The association between the nicotinic acetylcholine receptor α4 subunit gene (CHRNA4) rs1044396 and Internet gaming disorder in Korean male adults

-two target genes used in both study 1 and study 2. (DOCX) 10 / 15 S1 File. Raw data. (XLSX) Author Contributions Conceptualization: Jo-Eun Jeong, Je-Keun Rhee, Tae-Min Kim, Jung Ah Min, Dai-Jin Kim ... . Data curation: Jo-Eun Jeong, Je-Keun Rhee, Su-Min Kwak, Sol-hee Bang, Hyun Cho. Formal analysis: Jo-Eun Jeong, Je-Keun Rhee, Tae-Min Kim. Funding acquisition: Dai-Jin Kim. Investigation: Jo-Eun Jeong

Identification of rare germline copy number variations over-represented in five human cancer types

Background Copy number variations (CNVs) are increasingly recognized as significant disease susceptibility markers in many complex disorders including cancer. The availability of a large number of chromosomal copy number profiles in both malignant and normal tissues in cancer patients presents an opportunity to characterize not only somatic alterations but also germline CNVs...

MR Imaging Analysis of Non-Measurable Enhancing Lesions Newly Appearing after Concomitant Chemoradiotherapy in Glioblastoma Patients for Prognosis Prediction

Purpose To analyze the enhancement patterns and apparent diffusion coefficient (ADC) values of non-measurable surgical cavity wall enhancement pattern, newly appearing after completion of standard concurrent chemoradiotherapy (CCRT) with temozolomide in glioblastoma patients for the prognosis prediction. Materials and Methods From January 2010 to April 2014, among 190 patients...

Intravenous leiomyomatosis: an unusual intermediate between benign and malignant uterine smooth muscle tumors

Intravenous leiomyomatosis is an unusual smooth muscle neoplasm with quasi-malignant intravascular growth but a histologically banal appearance. Herein, we report expression and molecular cytogenetic analyses of a series of 12 intravenous leiomyomatosis cases to better understand the pathogenesis of intravenous leiomyomatosis. All cases were analyzed for the expression of HMGA2...

Predictive and Prognostic Value of Ribonucleotide Reductase Regulatory Subunit M1 and Excision Repair Cross-Complementation Group 1 in Advanced Urothelial Carcinoma (UC) Treated with First-Line Gemcitabine Plus Platinum Combination Chemotherapy

Preclinical and clinical studies have suggested that expression of ribonucleotide reductase regulatory subunit M1 (RRM1) and excision repair cross-complementation group 1 (ERCC1) is associated with resistance to gemcitabine and cisplatin, respectively. We evaluated the significance of RRM1 and ERCC1 expression to predict tumor response to gemcitabine plus platinum chemotherapy...

Predictive and prognostic value of PET/CT imaging post-chemoradiotherapy and clinical decision-making consequences in locally advanced head & neck squamous cell carcinoma: a retrospective study

Background The accuracy of 18 F-fluorodeoxygluocose positron emission tomography/computed tomography (PET/CT) in predicting immediate failure after radical chemoradiotherapy (CRT) for HNSCC is poorly characterized at present. The purpose of this study was to examine PET/CT as a predictive and prognostic gauge of immediate failure after CRT and determine the impact of these...

MR Imaging Evaluation of Intracerebral Hemorrhages and T2 Hyperintense White Matter Lesions Appearing after Radiation Therapy in Adult Patients with Primary Brain Tumors

The purpose of our study was to determine the frequency and severity of intracerebral hemorrhages and T2 hyperintense white matter lesions (WMLs) following radiation therapy for brain tumors in adult patients. Of 648 adult brain tumor patients who received radiation therapy at our institute, magnetic resonance (MR) image data consisting of a gradient echo (GRE) and FLAIR T2...

Detecting structural variations in the human genome using next generation sequencing

sequencing data and applications of statistics and bioinformatics methods to cancer genetics and epigenetics. Tae-Min Kim is a postdoctoral research associate at the Center for Biomedical Informatics, Harvard

Clinicopathologic analysis of programmed cell death-1 and programmed cell death-ligand 1 and 2 expressions in pulmonary adenocarcinoma: comparison with histology and driver oncogenic alteration status

Immunotherapies targeting the programmed cell death-1/programmed cell death-ligand 1 pathway have emerged as promising therapeutic strategies for lung cancer. However, the expression pattern and prognostic implications of programmed cell death-ligand 1 and 2 and programmed cell death-1 in comparison with the histology and genetic alterations in pulmonary adenocarcinomas remains...

Prognosis Prediction of Measurable Enhancing Lesion after Completion of Standard Concomitant Chemoradiotherapy and Adjuvant Temozolomide in Glioblastoma Patients: Application of Dynamic Susceptibility Contrast Perfusion and Diffusion-Weighted Imaging

Purpose To assess the prognosis predictability of a measurable enhancing lesion using histogram parameters produced by the normalized cerebral blood volume (nCBV) and normalized apparent diffusion coefficient (nADC) after completion of standard concomitant chemoradiotherapy (CCRT) and adjuvant temozolomide (TMZ) medication in glioblastoma multiforme (GBM) patients. Materials and...

rSW-seq: Algorithm for detection of copy number alterations in deep sequencing data

Background Recent advances in sequencing technologies have enabled generation of large-scale genome sequencing data. These data can be used to characterize a variety of genomic features, including the DNA copy number profile of a cancer genome. A robust and reliable method for screening chromosomal alterations would allow a detailed characterization of the cancer genome with...

De novo copy number variations in cloned dogs from the same nuclear donor

Background Somatic mosaicism of copy number variants (CNVs) in human body organs and de novo CNV event in monozygotic twins suggest that de novo CNVs can occur during mitotic recombination. These de novo CNV events are important for understanding genetic background of evolution and diverse phenotypes. In this study, we explored de novo CNV event in cloned dogs with identical...