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Analytic estimation of transition between instantaneous eigenstates of quantum two-level system

Transition amplitudes between instantaneous eigenstates of a quantum two-level system are evaluated analytically on the basis of a new parametrization of its evolution operator, which has recently been proposed to construct exact solutions. In particular, the condition under which the transitions are suppressed is examined analytically. It is shown that the analytic expression of...

Analysis of the dynamic characteristics of seawater intrusion using partial wavelet coherence: a case study at Nakaura Watergate, Japan

Lake Shinji and Lake Nakaumi are coupled brackish lakes on the Japan Sea coast of Japan. Seawater from the Japan Sea frequently intrudes into Lake Nakaumi through the bottom. Salinity flux at Nakaura Watergate was analysed. Effects of river discharge, tide level, and meteorological forcing variables makes the seawater intrusion non-linear. To account for the non-linear...

Heart-Derived Stem Cells in Miniature Swine with Coronary Microembolization: Novel Ischemic Cardiomyopathy Model to Assess the Efficacy of Cell-Based Therapy

. Leiker, and Takayuki Suzuki Division of Cardiovascular Medicine, University at Buffalo Clinical and Translational Research Center, Suite 7030, 875 Ellicott Street, Buffalo, NY 14203, USA Received 27 June ... , data acquisition, and data analysis; Takayuki Suzuki was responsible for experimental studies, data acquisition, and data analysis. All authors read and approved the study. Acknowledgments These studies

Heart-Derived Stem Cells in Miniature Swine with Coronary Microembolization: Novel Ischemic Cardiomyopathy Model to Assess the Efficacy of Cell-Based Therapy

. Leiker, and Takayuki Suzuki Division of Cardiovascular Medicine, University at Buffalo Clinical and Translational Research Center, Suite 7030, 875 Ellicott Street, Buffalo, NY 14203, USA Received 27 June ... , data acquisition, and data analysis; Takayuki Suzuki was responsible for experimental studies, data acquisition, and data analysis. All authors read and approved the study. Acknowledgments These studies

Quantitative analysis of tissue deformation dynamics reveals three characteristic growth modes and globally aligned anisotropic tissue deformation during chick limb development

Tissue-level characterization of deformation dynamics is crucial for understanding organ morphogenetic mechanisms, especially the interhierarchical links among molecular activities, cellular behaviors and tissue/organ morphogenetic processes. Limb development is a well-studied topic in vertebrate organogenesis. Nevertheless, there is still little understanding of tissue-level...

Severe Fournier’s gangrene in a patient with rectal cancer: case report and literature review

Background Fournier’s gangrene in the setting of rectal cancer is rare. Treatment for Fournier’s gangrene associated with rectal cancer is more complex than other cases of Fournier’s gangrene. We report on a patient with severe Fournier’s gangrene in the setting of locally advanced rectal cancer who was treated with a combined modality therapy. Case presentation A 65-year-old man...

Cell Type-Specific Subcellular Localization of Phospho-TBK1 in Response to Cytoplasmic Viral DNA

Cytoplasmic viral RNA and DNA are recognized by RIG-I-like receptors and DNA sensors that include DAI, IFI16, DDX41, and cGAS. The RNA and DNA sensors evoke innate immune responses through the IPS-1 and STING adaptors. IPS-1 and STING activate TBK1 kinase. TBK1 is phosphorylated in its activation loop, leading to IRF3/7 activation and Type I interferon (IFN) production. IPS-1 and...

Advanced small-cell colon carcinoma: a case report

Introduction Small-cell colon carcinoma is a very rare disease among colon neoplasms; it is difficult to achieve long-term survival due to its aggressive tumor behavior. Here we report the long-term survival of a patient with advanced small-cell colon carcinoma achieved by a combination of surgery and continuous chemotherapy. Case presentation A 67-year-old Japanese man underwent...

Reconstruction and in vivo analysis of the extinct tbx5 gene from ancient wingless moa (Aves: Dinornithiformes)

Background The forelimb-specific gene tbx5 is highly conserved and essential for the development of forelimbs in zebrafish, mice, and humans. Amongst birds, a single order, Dinornithiformes, comprising the extinct wingless moa of New Zealand, are unique in having no skeletal evidence of forelimb-like structures. Results To determine the sequence of tbx5 in moa, we used a range of...

Risk factors for parastomal hernia in Japanese patients with permanent colostomy

Kimihiko Funahashi Takayuki Suzuki Yasuo Nagashima Satoshi Matsuda Junichi Koike Hiroyuki Shiokawa Mitsunori Ushigome Kenichiro Arai Tomoaki Kaneko Akiharu Kurihara Hironori Kaneko Purpose Although

Genetic correction of splice site mutation in purified and enriched myoblasts isolated from mdx5cv mice

Background Duchenne Muscular Dystrophy (DMD) is an X-linked genetic disorder that results in the production of a dysfunctional form of the protein, dystrophin. The mdx5cv mouse is a model of DMD in which a point mutation in exon 10 of the dystrophin gene creates an artificial splice site. As a result, a 53 base pair deletion of exon 10 occurs with a coincident creation of a...

E22Δ Mutation in Amyloid β-Protein Promotes β-Sheet Transformation, Radical Production, and Synaptotoxicity, But Not Neurotoxicity

October 2010; Accepted 16 November 2010 Academic Editor: Katsuhiko Yanagisawa Copyright © 2011 Takayuki Suzuki et al. This is an open access article distributed under the Creative Commons Attribution

E22Δ Mutation in Amyloid β-Protein Promotes β-Sheet Transformation, Radical Production, and Synaptotoxicity, But Not Neurotoxicity

October 2010; Accepted 16 November 2010 Academic Editor: Katsuhiko Yanagisawa Copyright © 2011 Takayuki Suzuki et al. This is an open access article distributed under the Creative Commons Attribution

Role of atrophic changes in proximal tubular cells in the peritubular deposition of type IV collagen in a rat renal ablation model

Background. Tubular atrophy, dilation and interstitial fibrosis are common in tubulointerstitial lesions, but the precise roles and inter-relationships of these components in the development of interstitial lesions have not been determined. This study focused on the origin and roles of atrophic tubules in the peritubular deposition of type IV collagen in a rat renal ablation...

Low free thyroxine concentratios and deficient nocturnal surge of thyroid‐stimulating hormone in haemodialysed patients compared with undialysed patients

Background. There is little information on the differences in pituitary–thyroid function between undialysed and haemodialysed patients. Methods. Serum concentrations of free thyroxine (T4) and free triiodothyronine (T3), measured by enhanced chemiluminescence immunoassay, and thyroid‐stimulating hormone (TSH) were compared in undialysed (n=22) and haemodialysed patients (n=85...