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Search: authors:"Takeshi Yamaura"

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Evaluation of therapeutic effects of FAK inhibition in murine models of atherosclerosis

ObjectiveTherapeutic effects of focal adhesion kinase (FAK) inhibition using a small molecule inhibitor was evaluated in apolipoprotein E (apoE) knockout (KO) and low-density lipoprotein receptor (LDLr) KO mouse atherosclerosis models.ResultsThe prevention trial consisted of an 8-week treatment with an FAK inhibitor concurrent treatment with a high fat (HF)/high cholesterol (HC...