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Malaria among foreign migrant workers in Savannakhet Province, Lao People’s Democratic Republic

BackgroundAlthough mobile and migrant populations are considered an important group in malaria elimination settings, there is currently a lack of understanding about foreign migrant workers in the Lao People’s Democratic Republic (Lao PDR). The present study aimed to document the migration characteristics, positive rate of malaria infection, and preventive and treatment-seeking...

Patients’ adherence to artemisinin-based combination therapy and healthcare workers’ perception and practice in Savannakhet province, Lao PDR

BackgroundArtemisinin resistance in Plasmodium falciparum has been spreading across Southeast Asia. Patients’ adherence to artemisinin-based combination therapy (ACT) is critical to avoid expanding this resistance. The objectives of this research were to examine patients’ adherence to ACT for the treatment of uncomplicated malaria and to examine the healthcare workers’ perception...

Human infection with Plasmodium knowlesi on the Laos-Vietnam border

BackgroundBorder malaria in the Greater Mekong region of Southeast Asia poses a serious threat to the health of the ethnic minority populations of the region. Traditionally thought to be caused primarily by the malaria parasites Plasmodium falciparum and Plasmodium vivax, recently a zoonotic parasite, Plasmodium knowlesi, has been identified in some countries of the region. The...

Perceptions of asymptomatic malaria infection and their implications for malaria control and elimination in Laos

Soundala, Thomas J. Peto, Lorenz von Seidlein. Project administration: Koukeo Phommasone, Tiengkham Pongvongsa, Palingnaphone Koummarasy, Paul N. Newton, Mayfong Mayxay. Resources: Bipin Adhikari ... , Tiengkham Pongvongsa, Gisela Henriques, Thomas J. Peto, Lorenz von Seidlein, Nicholas P. J. Day, Arjen M. Dondorp, Paul N. Newton, Mayfong Mayxay, Christopher Pell. Supervision: Koukeo Phommasone, Tiengkham

Individual and household factors associated with incidences of village malaria in Xepon district, Savannakhet province, Lao PDR

Background In the Lao PDR, the incidence of malaria greatly differs among villages even within a subdistrict, and the reasons for this difference are poorly understood. The objective of this study was to identify differences in villagers’ behavior and the household environment between villages with high incidences and those with low incidences of malaria in a rural district of...

Towards malaria elimination in Savannakhet, Lao PDR: mathematical modelling driven strategy design

The number of Plasmodium falciparum malaria cases around the world has decreased substantially over the last 15 years, but with the spread of resistance against anti-malarial drugs and insecticides, this decline may not continue. There is an urgent need to consider alternative, accelerated strategies to eliminate malaria in countries like Lao PDR, where there are a few remaining...

Towards malaria elimination in Savannakhet, Lao PDR: mathematical modelling driven strategy design

The number of Plasmodium falciparum malaria cases around the world has decreased substantially over the last 15 years, but with the spread of resistance against anti-malarial drugs and insecticides, this decline may not continue. There is an urgent need to consider alternative, accelerated strategies to eliminate malaria in countries like Lao PDR, where there are a few remaining...

Towards malaria elimination in Savannakhet, Lao PDR: mathematical modelling driven strategy design

The number of Plasmodium falciparum malaria cases around the world has decreased substantially over the last 15 years, but with the spread of resistance against anti-malarial drugs and insecticides, this decline may not continue. There is an urgent need to consider alternative, accelerated strategies to eliminate malaria in countries like Lao PDR, where there are a few remaining...

Towards malaria elimination in Savannakhet, Lao PDR: mathematical modelling driven strategy design

The number of Plasmodium falciparum malaria cases around the world has decreased substantially over the last 15 years, but with the spread of resistance against anti-malarial drugs and insecticides, this decline may not continue. There is an urgent need to consider alternative, accelerated strategies to eliminate malaria in countries like Lao PDR, where there are a few remaining...

Towards malaria elimination in Savannakhet, Lao PDR: mathematical modelling driven strategy design

The number of Plasmodium falciparum malaria cases around the world has decreased substantially over the last 15 years, but with the spread of resistance against anti-malarial drugs and insecticides, this decline may not continue. There is an urgent need to consider alternative, accelerated strategies to eliminate malaria in countries like Lao PDR, where there are a few remaining...

Household clustering of asymptomatic malaria infections in Xepon district, Savannakhet province, Lao PDR

Background In the Lao PDR, malaria morbidity and mortality have remarkably decreased over the past decade. However, asymptomatic infections in rural villages contribute to the on-going local transmission. The primary objective of this study was to explore the characteristics of infections in a malaria-endemic district of the Lao PDR. The specific objectives were to investigate...

Asymptomatic malaria, growth status, and anaemia among children in Lao People’s Democratic Republic: a cross-sectional study

Tiengkham Pongvongsa Souraxay Phrommala Tomoyo Taniguchi Yuba Inamine 0 Rie Takeuchi Tadashi Watanabe Futoshi Nishimoto Kazuhiko Moji Shigeyuki Kano Hisami Watanabe 0 Jun Kobayashi 0 Center of Molecular

Asymptomatic Plasmodium infections in 18 villages of southern Savannakhet Province, Lao PDR (Laos)

Background A large fraction of Plasmodium infections do not cause clinical signs and symptoms of disease and persist at densities in blood that are not detectable by microscopy or rapid diagnostic tests. These infections may be critical as a transmission reservoir in areas of low malaria endemicity. Understanding the epidemiology of these infections would be helpful for malaria...

Village health volunteers’ social capital related to their performance in Lao People’s Democratic Republic: a cross-sectional study

Yu Sato Tiengkham Pongvongsa Daisuke Nonaka Sengchanh Kounnavong Phetsomphone Nansounthavong Kazuhiko Moji Panom Phongmany Yasuhiko Kamiya Miho Sato Jun Kobayashi 0 1 0 Bureau of International

Thiamin supplementation does not reduce the frequency of adverse events after anti-malarial therapy among patients with falciparum malaria in southern Laos

Maniphone Khanthavong 8 Lorna Cox 7 Odai Sichanthongthip 8 Mallika Imwong 6 Tiengkham Pongvongsa 5 Bouasy Hongvanthong 8 Samlane Phompida 8 Viengxay Vanisaveth 8 Nicholas J White 1 2 4 9 Paul N Newton 1 2 4

Joint malaria surveys lead towards improved cross-border cooperation between Savannakhet province, Laos and Quang Tri province, Vietnam

Background In Savannakhet province, Laos and Quang Tri province, Vietnam, malaria is still an important health problem and most cases are found in the mountainous, forested border areas where ethnic minority groups live. The objectives of this study were to obtain a better joint understanding of the malaria situation along the border and, on the basis of that, improve malaria...

Evaluation of a rapid colorimetric field test to assess the effective life of long-lasting insecticide-treated mosquito nets in the Lao PDR

Beach 0 Tiengkham Pongvongsa Samlane Phompida Bouasy Hongvanthong Viengxay Vanisaveth Paul N Newton Lucrecia Vizcaino 0 Isabel Swamidoss 0 0 Division of Parasitic Diseases and Malaria, Centers for Disease

Efficacy of artemether-lumefantrine, the nationally-recommended artemisinin combination for the treatment of uncomplicated falciparum malaria, in southern Laos

Background The Lao Government changed the national policy for uncomplicated Plasmodium falciparum malaria from chloroquine to artemether-lumefantrine (AL) in 2005. Since then, no information on AL efficacy has been reported. With evidence of resistance to artemisinin derivatives in adjacent Cambodia, there has been a concern as to AL efficacy. Monitoring of AL efficacy would help...

No Evidence for Spread of Plasmodium falciparum Artemisinin Resistance to Savannakhet Province, Southern Laos

7LJ, United Kingdom; and Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, E-mails: and kasia@ tropmedres.ac. Tiengkham Pongvongsa, Savannakhet Provincial Malaria Station