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Direct conversion of pig fibroblasts to chondrocyte-like cells by c-Myc

Foundation of Guangdong Province of China (Grant No. A2017420, to J.S.J.; Grant No. B2014238, to H.F.S.). Author information Author notes These authors contributed equally: Jun-Wen Shi, Ting-Ting Zhang, Wei ... , Guangzhou, 510515, ChinaJun-Wen Shi, Ting-Ting Zhang, Jie Yang, Xiao-Lin Lin, Jun-Shuang Jia, Hong-Fen Shen, Sheng-Chun Wang, Jing Li, Wen-Tao Zhao & Dong XiaoInstitute of Comparative Medicine & Laboratory

Mediastinal Lymph Node Metastases in Thyroid Cancer: Characteristics, Predictive Factors, and Prognosis

Cappelli Copyright © 2017 Ting-ting Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in

Mediastinal Lymph Node Metastases in Thyroid Cancer: Characteristics, Predictive Factors, and Prognosis

Cappelli Copyright © 2017 Ting-ting Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in

Mediastinal Lymph Node Metastases in Thyroid Cancer: Characteristics, Predictive Factors, and Prognosis

Cappelli Copyright © 2017 Ting-ting Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in

Bimetal-organic-framework derived CoTiO3 mesoporous micro-prisms anode for superior stable power sodium ion batteries

materials for various energy storage systems, such as lithium ion batteries, sodium ion batteries, magnesium batteries and supercapacitors. Ting-Ting Zhang received her BE degree from Nanjing University of

Role of Acupoint Area Collagen Fibers in Anti-Inflammation of Acupuncture Lifting and Thrusting Manipulation

The role of the acupoint area collagen fibers in the efficacy of acupuncture lifting and thrusting (L&T) manipulation will be explored in this paper. 30 male NZW rabbits were randomly divided into 6 groups: sham operation group (Group N), model group (Group M), acupuncture without manipulation group (Group W), acupuncture L&T manipulation group (Group A), collagenase pretreatment...

Role of Acupoint Area Collagen Fibers in Anti-Inflammation of Acupuncture Lifting and Thrusting Manipulation

The role of the acupoint area collagen fibers in the efficacy of acupuncture lifting and thrusting (L&T) manipulation will be explored in this paper. 30 male NZW rabbits were randomly divided into 6 groups: sham operation group (Group N), model group (Group M), acupuncture without manipulation group (Group W), acupuncture L&T manipulation group (Group A), collagenase pretreatment...

Bisindolylmaleimide alkaloid BMA-155Cl induces autophagy and apoptosis in human hepatocarcinoma HepG-2 cells through the NF-κB p65 pathway

. Xiao SUN and Lin LI conducted the research, analyzed the data and wrote the paper. Hong-guang MA and Wei-ming ZHU provided the compounds. Pu SUN, Qi-lin WANG, and Ting-ting ZHANG assisted with portions ... Ocean, Shandong University, Weihai 264209, ChinaXiao Sun, Lin Li, Pu Sun, Qi-lin Wang, Ting-ting Zhang & Xia LiSchool of Medicine and Pharmacy, Ocean University of China, Qingdao 266000, ChinaHong-guang

Potentiation of synaptic transmission in Rat anterior cingulate cortex by chronic itch

Itch and pain share similar mechanisms. It has been well documented that the anterior cingulate cortex (ACC) is important for pain-related perception. ACC has also been approved to be a potential pruritus-associated brain region. However, the mechanism of sensitization in pruriceptive neurons in the ACC is not clear. In current study, a chronic itch model was established by...

Evaluation of the analgesic effects of ammoxetine, a novel potent serotonin and norepinephrine reuptake inhibitor

Foundation of China (No 81302761, 81274117, and 30973516). Author contribution Ting-ting ZHANG contributed to the research design, performance of the experiments, data analysis and manuscript writing. Rui

Dynamic Expression of BCL6 in Murine Conventional Dendritic Cells during In Vivo Development and Activation

The transcriptional repressor BCL6 plays an essential role in the development of germinal center B cells and follicular helper T cells. However, much less is known about the expression and function of BCL6 in other cell types. Here we report that during murine dendritic cell (DC) ontogeny in vivo, BCL6 is not expressed in bone marrow hematopoietic stem cells, common DC precursors...

Pharmacokinetics Study of Recombinant Hirudin in the Plasma of Rats Using Chromogenic Substrate, ELISA, and Radioisotope Assays

Aim To compare the analytical methods used to study the pharmacokinetics of recombinant hirudin in the plasma of rats that had been injected with 125I-recombinant hirudin. Methods 2.0 mg/kg 125I-recombinant hirudin were injected intravenously into rats. The recombinant hirudins in the plasma was analyzed by chromogenic substrate assay, enzyme-linked immunosorbent assay (ELISA...

Preliminary Study of Quercetin Affecting the Hypothalamic-Pituitary-Gonadal Axis on Rat Endometriosis Model

Zhang,1 and Yan Zhu3 1Department of Obstetrics and Gynecology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai

Bifunctional fused polypeptide inhibits the growth and metastasis of breast cancer

Bifunctional fused polypeptide inhibits the growth and metastasis of breast cancer Ai-Ling Liang,1–3,* Hai-Li Qian,4,* Ting-Ting Zhang,1–3 Ning Zhou,1–3 Hai-Juan Wang,4 Xi-Ting Men,4 Wei Qi,5 Ping

Spectral Discrimination of the Invasive Plant Spartina alterniflora at Multiple Phenological Stages in a Saltmarsh Wetland

Spartina alterniflora has widely invaded the saltmarshes of the Yangtze River Estuary and brought negative effects to the ecosystem. Remote sensing technique has recently been used to monitor its distribution, but the similar morphology and canopy structure among S. alterniflora and its neighbor species make it difficult even with high-resolution images. Nevertheless, these...

Identification of Land-Cover Characteristics Using MODIS Time Series Data: An Application in the Yangtze River Estuary

Land-cover characteristics have been considered in many ecological studies. Methods to identify these characteristics by using remotely sensed time series data have previously been proposed. However, these methods often have a mathematical basis, and more effort is required to better illustrate the ecological meanings of land-cover characteristics. In this study, a method for...

Retrospective analysis of 102 cases of solid pseudopapillary neoplasm of the pancreas in China

Objective Clinicopathological features and surgical outcomes in patients with solid pseudopapillary neoplasm (SPN) of the pancreas were analysed.

MicroRNA-122 Triggers Mesenchymal-Epithelial Transition and Suppresses Hepatocellular Carcinoma Cell Motility and Invasion by Targeting RhoA

The loss of microRNA-122 (miR-122) expression is strongly associated with increased invasion and metastasis, and poor prognosis of hepatocellular carcinoma (HCC), however, the underlying mechanisms remain poorly understood. In the present study, we observed that miR-122 over-expression in HCC cell lines Sk-hep-1 and Bel-7402 triggered the mesenchymal-epithelial transition (MET...

Pharmacokinetic behaviors and oral bioavailability of oridonin in rat plasma

Aim:To study the intravenous and oral pharmacokinetic behavior of oridonin and its extent of absolute oral bioavailability in rats.Methods:Oridonin was administered to rats via iv (5, 10 and 15 mg/kg), po (20, 40 and 80 mg/kg) or ip administration (10 mg/kg). The concentrations of oridonin in rat plasma were determined by a high performance liquid chromatography with electrospray...