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Search: authors:"Toru Sakairi"

2 papers found.
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Enhancement of HGF-induced tubulogenesis by endothelial cell-derived GDNF

. Author Contributions Investigation: Masao Nakasatomi, Shunsuke Takahashi. Supervision: Akito Maeshima. Validation: Toru Sakairi, Hidekazu Ikeuchi, Yoriaki Kaneko, Keiju Hiromura, Yoshihisa Nojima

TGF-beta1 reduces Wilms' tumor suppressor gene expression in podocytes

Background. Wilms' tumor suppressor gene (WT1) is essential for normal podocyte function, and transforming growth factor (TGF)-beta contributes to focal segmental glomerulosclerosis (FSGS). We aimed to address whether TGF-beta affects WT1 expression in podocytes. Methods. A human podocyte cell line treated with TGF-beta1 and kidneys in Alb/TGF-beta1-transgenic mice were analyzed...