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6 papers found.
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Biomarkers of Chronic Inflammatory State in Uremia and Cardiovascular Disease

Cardiovascular disease is the leading cause of death in the general population; traditional risk factors seem inadequate to explain completely the remarkable prevalence of cardiovascular mortality and morbidity observed in the uremic population. A role for chronic inflammation has been well established in the development of atherosclerotic disease, and, on the basis of these...

Biomarkers of Chronic Inflammatory State in Uremia and Cardiovascular Disease

State in Uremia and Cardiovascular Disease Vincenzo Panichi, Alessia Scatena, Massimiliano Migliori, Valentina Marchetti, Sabrina Paoletti, and Sara Beati Nephrology and Dialysis Unit, Versilia Hospital

Benfotiamine Counteracts Glucose Toxicity Effects on Endothelial Progenitor Cell Differentiation via Akt/FoxO Signaling

Dysfunction of mature endothelial cells is thought to play a major role in both micro- and macrovascular complications of diabetes. However, recent advances in biology of endothelial progenitor cells (EPCs) have highlighted their involvement in diabetes complications. To determine the effect of glucotoxicity on EPCs, human EPCs have been isolated from peripheral blood mononuclear...

Anaemia and resistance to erythropoiesis-stimulating agents as prognostic factors in haemodialysis patients: results from the RISCAVID study

Background. Resistance to erythropoiesis-stimulating agents (ESAs) is often associated with chronic inflammation. Here, we investigated how anaemia, ESA resistance and the plasma levels of biological markers of inflammation could influence all-cause and cardiovascular disease morbidity and mortality. Methods. Seven hundred and fifty-three haemodialysis (HD) patients (mean age 66...

Immunotherapy

Recent reports in epidemiology suggest yet unexplained roles of immunosurveillance in gliomagenesis and survival of glioma patients. For instance, the use of nonsteroidal anti-inflammatory drugs (NSAIDs) is shown to be associated with reduced occurrences of gliomas in humans. NSAIDs mediate their biological effects partially by suppressing cyclooxygenase 2 (COX2) and its product...

Angiogenesis and Invasion

HUMAN PROGENITOR CELLS FOR CELL-BASED DELIVERY OF ANGIOSTATIC GENES TO BRAIN TUMORS Valentina Marchetti , Faith Barnett , Matthew Wang , Lea Scheppke , Javier Sanchez-Cespedes , Charles De Rossi , Glen