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Search: authors:"Viviana Casagrande"

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ITCH Deficiency Protects From Diet-Induced Obesity

Classically activated macrophages (M1) secrete proinflammatory cytokine and are predominant in obese adipose tissue. M2 macrophages, prevalent in lean adipose tissue, are induced by IL-13 and IL-4, mainly secreted by Th2 lymphocytes, and produce the anti-inflammatory cytokine IL-10. ITCH is a ubiquitously expressed E3 ubiquitin ligase involved in T-cell differentiation and in a...

TIMP3 Overexpression in Macrophages Protects From Insulin Resistance, Adipose Inflammation, and Nonalcoholic Fatty Liver Disease in Mice

Rossella Menghini Viviana Casagrande Stefano Menini Arianna Marino Valeria Marzano Marta L. Hribal Paolo Gentileschi Davide Lauro Orazio Schillaci Giuseppe Pugliese Paolo Sbraccia Andrea Urbani

TIMP3 Is Reduced in Atherosclerotic Plaques From Subjects With Type 2 Diabetes and Increased by SirT1

Marina Cardellini Rossella Menghini Eugenio Martelli Viviana Casagrande Arianna Marino Stefano Rizza Ottavia Porzio Alessandro Mauriello Anna Solini Arnaldo Ippoliti Renato Lauro Franco Folli Massimo