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35 papers found.
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Shear Wave Elasticity Measurements of Three-Dimensional Cancer Cell Cultures Using Laser Speckle Contrast Imaging

Shear wave elastography (SWE) has been widely adopted for clinical in vivo imaging of tissue elasticity for disease diagnosis, and this modality can be a valuable tool for in vitro mechanobiology studies but its full potential has yet to be explored. Here we present a laser speckle contrast SWE system for noncontact monitoring the spatiotemporal changes of the extracellular...

A broadband photodetector based on Rhodamine B-sensitized ZnO nanowires film

figures independently. Ze Wen Liu is the corresponding author for this paper. All authors reviewed the manuscript. Additional Information Competing Interests: The authors declare that they have no

Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution

Scholar Search for Kazuo Shin-Ya in:Nature Research journals • PubMed • Google Scholar Search for Wen Liu in:Nature Research journals • PubMed • Google Scholar Search for Ikuro Abe in:Nature Research

Allosteric modulation of protein-protein interactions by individual lipid binding events

AffiliationsInstitute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX, 77030, USAXiao Cong, Yang Liu, Wen Liu, Xiaowen Liang & Arthur LaganowskyDepartment of Chemistry, Texas A&M University ... Search for Wen Liu in:Nature Research journals • PubMed • Google Scholar Search for Xiaowen Liang in:Nature Research journals • PubMed • Google Scholar Search for Arthur Laganowsky in:Nature Research

An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease

Boyd, Valentina N. Lagomarsino, Tiernan T. O’Malley, Wen Liu, Tracy Young-Pearse, Dennis J. Selkoe & Dominic M. WalshMassachusetts General Institute for Neurodegenerative Disease, Massachusetts General ... Wen Liu in:Nature Research journals • PubMed • Google Scholar Search for Charles R. Vanderburg in:Nature Research journals • PubMed • Google Scholar Search for Matthew P. Frosch in:Nature Research

Molecular basis of dimer formation during the biosynthesis of benzofluorene-containing atypical angucyclines

Biology and Medicinal Chemistry, College of Pharmacy and Department of Chemistry, University of Texas at Austin, Austin, TX, 78712, USAHung-wen Liu AuthorsSearch for Chunshuai Huang in:Nature Research ... Zhang in:Nature Research journals • PubMed • Google Scholar Search for Cheng-Shan Yuan in:Nature Research journals • PubMed • Google Scholar Search for Hung-wen Liu in:Nature Research journals • PubMed

Nitrogen-doped tungsten carbide nanoarray as an efficient bifunctional electrocatalyst for water splitting in acid

Gao Zhao Cai Ying Zhang Victor S. Batista Wen Liu Xiaoming Sun Tungsten carbide is one of the most promising electrocatalysts for the hydrogen evolution reaction, although it exhibits sluggish

Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis

Wenjie Guo and Wen Liu contributed equally to this work. AffiliationsState Key Laboratory of Pharmaceutical Biotechnology and Collaborative Innovation Center of Chemistry for Life Sciences, School of Life ... Sciences, Nanjing University, Nanjing, 210023, ChinaWenjie Guo, Wen Liu, Shuang Peng, Lihong Shen, Yan Shen, Xingqi Wang, Yang Sun & Qiang XuDepartment of Diabetes Complications and Metabolism, Beckman

Salvianolic acid B inhibits mitochondrial dysfunction by up-regulating mortalin

Wen Liu supervised the entire study and were involved in design, acquisition of data, data analysis and interpretation and drafting the manuscript. All authors reviewed and approved the manuscript

The influence of postharvest UV-C treatment on anthocyanin biosynthesis in fresh-cut red cabbage

Red cabbage (Brassica oleracea L. var. capitata f. rubra DC.) is a fresh edible vegetable consumed globally that contains high levels of antioxidant compounds including anthocyanins. In this study, fresh-cut red cabbage was treated with different Ultraviolet-C (UV-C) dosages. Fifteen cyanidin derivatives were observed in UV-C treated fresh-cut red cabbage; four of these were...

Nanoscale zero-valent iron/persulfate enhanced upflow anaerobic sludge blanket reactor for dye removal: Insight into microbial metabolism and microbial community

This study investigated the efficiency of nanoscale zero-valent iron combined with persulfate (NZVI/PS) for enhanced degradation of brilliant red X-3B in an upflow anaerobic sludge blanket (UASB) reactor, and examined the effects of NZVI/PS on anaerobic microbial communities during the treatment process. The addition of NZVI (0.5 g/L) greatly enhanced the decolourization rate of...

Association between gut microbiota and diapause preparation in the cabbage beetle: a new perspective for studying insect diapause

Gut microbiota mediate the nutritional metabolism and play important roles in human obesity. Diapausing insects accumulate large fat reserves and develop obese phenotypes in order to survive unfavorable conditions. However, the possibility of an association between gut microbiota and insect diapause has not been investigated. We used the Illumina MiSeq platform to compare gut...

Levofloxacin loaded mesoporous silica microspheres/nano-hydroxyapatite/polyurethane composite scaffold for the treatment of chronic osteomyelitis with bone defects

, ChinaQi Wang, Cheng Chen, Wen Liu, Xiaoqiang He, Nian Zhou, Dongli Zhang & Wei HuangState Key Laboratory of Oncogenes and Related Genes School of Biomedical Engineering and Med-X Research Institute Shanghai ... AuthorsSearch for Qi Wang in:Nature Research journals • PubMed • Google ScholarSearch for Cheng Chen in:Nature Research journals • PubMed • Google ScholarSearch for Wen Liu in:Nature Research journals • PubMed

Arbuscular mycorrhizal fungi enhance soil carbon sequestration in the coalfields, northwest China

Carbon storage is affected by photosynthesis (Pn) and soil respiration (Rs), which have been studied extensively in natural and agricultural systems. However, the effects of Pn and Rs on carbon storages in the presence of arbuscular mycorrhizal fungi (AMF) in coalfields remain unclear. A field experiment was established in 2014 in Shendong coal mining subsidence area. The...

NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish

Expression of neuroendocrine-associated phosphatase (NEAP, also named as dual specificity phosphatase 26, [DUSP26]) is restricted to neuroendocrine tissues. We found that NEAP, but not its phosphatase-defective mutant, suppressed nerve growth factor (NGF) receptor TrkA and fibroblast growth factor receptor 1 (FGFR1) activation in PC12 cells upon NGF stimulation. Conversely...

The effects of manganese oxide octahedral molecular sieve chitosan microspheres on sludge bacterial community structures during sewage biological treatment

, Ministry of Education, Wuhan Textile University, Wuhan, 430073, ChinaFei PanEnvironmental Engineering Program, Department of Civil Engineering, Auburn University, Auburn, AL 36849, USAFei Pan, Wen Liu ...  & Dongye ZhaoSchool of Materials Science and Engineering, Wuhan Textile University, Wuhan 430073, ChinaXianze Yin AuthorsSearch for Fei Pan in:Nature Research journals • PubMed • Google ScholarSearch for Wen

Heat Shock Factor 1 Mediates Latent HIV Reactivation

HSF1, a conserved heat shock factor, has emerged as a key regulator of mammalian transcription in response to cellular metabolic status and stress. To our knowledge, it is not known whether HSF1 regulates viral transcription, particularly HIV-1 and its latent form. Here we reveal that HSF1 extensively participates in HIV transcription and is critical for HIV latent reactivation...

TIM-4 promotes the growth of non-small-cell lung cancer in a RGD motif-dependent manner

Background:T-cell immunoglobulin domain and mucin domain 4 (TIM-4) is exclusively expressed in antigen-presenting cells and involved in immune regulation. However, the role of TIM-4 expressed in tumour cells remains completely unknown.Methods:Immunohistochemistry staining was used to examine TIM-4 or Ki-67 expression in tumour tissues. Real-time PCR or RT-PCR was performed to...