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Combined effects of fruit and vegetables intake and physical activity on the risk of metabolic syndrome among Chinese adults

MetS. Author Contributions Conceptualization: Qi-qiang He. Data curation: Xin-tong Li, Wei Liao. Formal analysis: Xin-tong Li, Wei Liao, Hong-jie Yu, Ming-wei Liu, Shuai Yuan, Bo-wen Tang ... . Methodology: Xin-tong Li, Wei Liao, Hong-jie Yu, Ming-wei Liu, Shuai Yuan, Bo-wen Tang, Xu-hao Yang, Yong Song, Samuel D. Towne, Jr. Project administration: Zong-fu Mao, Qi-qiang He. Resources: Shi-le Cheng

Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses

Autophagy is a protein degradative process important for normal cellular metabolism. It is apparently used also by cells to eliminate invading pathogens. Interestingly, many pathogens have learned to subvert the cell’s autophagic process. Here, we review the interactions between viruses and cells in regards to cellular autophagy. Using findings from hepatitis B virus and human...

Wip1 and p53 contribute to HTLV-1 Tax-induced tumorigenesis

Background Human T-cell Leukemia Virus type 1 (HTLV-1) infects 20 million individuals world-wide and causes Adult T-cell Leukemia/Lymphoma (ATLL), a highly aggressive T-cell cancer. ATLL is refractory to treatment with conventional chemotherapy and fewer than 10% of afflicted individuals survive more than 5 years after diagnosis. HTLV-1 encodes a viral oncoprotein, Tax, that...