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Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast

Telomerase reverse transcriptase (TERT) and the non-coding telomerase RNA subunit (TR) constitute the core of telomerase. Here we now report that the putative F-box protein Pof8 is also a constitutive component of active telomerase in fission yeast. Pof8 functions in a hierarchical assembly pathway by promoting the binding of the Lsm2-8 complex to telomerase RNA, which in turn...

Adverse drug events in Chinese pediatric inpatients and associated risk factors: a retrospective review using the Global Trigger Tool

Guo Ping Wei Ting-ting Tang Xiao-jiang Tian Xue-wen Tang Yun-tao Jia OPEN Published: xx xx xxxx Understanding the epidemiology and risk factors of adverse drug events (ADEs) in pediatric inpatient is ... . Sampling: Ting-ting Tang, Huan-huan Ji. Record review: Huan-huan Ji, Yu-xia Guo, Ping Wei. Analysis and interpretation of data: Huan-huan Ji, Xue-wen Tang, Xiao-jiang Tian and Yun-tao Jia. All the authors

Sweroside ameliorates α-naphthylisothiocyanate-induced cholestatic liver injury in mice by regulating bile acids and suppressing pro-inflammatory responses

, Xiao-wen TANG, and Guang-yun WANG performed the experiments; Qiao-ling YANG, Jun-ting GONG, Xiao-wen TANG, and Guang-yun WANG acquired data; Qiao-ling YANG and Fan YANG analyzed data; Qiao-ling YANG, Fan ... Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, ChinaQiao-ling Yang, Fan Yang, Jun-ting Gong, Xiao-wen Tang, Guang-yun Wang, Zheng-tao

PdCo/Pd-Hexacyanocobaltate Hybrid Nanoflowers: Cyanogel-Bridged One-Pot Synthesis and Their Enhanced Catalytic Performance

Dong-Mei Sun 0 Lin Xu 0 Ya-Wen Tang 0 0 Jiangsu Key Laboratory of New Power Batteries, Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials, School of Chemistry and Materials

The Study of Aortic Stiffness in Different Hypertension Subtypes in Dialysis Patients

The aim of this study was to validate whether differences in aortic stiffness are responsible for the differences in cardiovascular mortality among hypertension subtypes. Twenty hundred and fifty continuous ambulatory peritoneal dialysis patients were included in the present study. They were classified into four groups: normotensives (n=92) with systolic blood pressure (SBP) <140...