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The research about radiometric technology of two-dimensional rotary table based on image gray level

It is difficult to measure infrared radiation quantitatively for fast dynamic targets such as aircraft and missile. At present, there are many problems such as low measurement accuracy, feedback delay, and complex measurement system. In this paper, a radiation measurement scheme based on image grayscale is proposed. The scheme adopts a two-dimensional turntable structure, which...

In vitro culture of Echinococcus multilocularis producing protoscoleces and mouse infection with the cultured vesicles

Zhuangzhi Zhang Donald P. McManus Hao Wen 0 Wenbao Zhang 0 0 State Key Laboratory Incubation Base of Xinjiang Major Diseases Research, Clinical Medical Research Institute, The First Affiliated Hospital of

The variations of IL-23R are associated with susceptibility and severe clinical forms of pulmonary tuberculosis in Chinese Uygurs

Background The incidence of tuberculosis (TB) remains high among Chinese Uygurs (a long-dwelling ethnic minority in Xinjiang) in China and the variants in IL-23R likely contribute to individual’s diversity in host response during infection. Methods A hospital based one to one matched case–control study was performed to assess the role of single nucleotide polymorphisms (SNPs) and...

Immunology and Immunodiagnosis of Cystic Echinococcosis: An Update

, Brisbane, QLD 4029, Australia Received 7 July 2011; Accepted 28 September 2011 Academic Editor: Antonio Cascio Copyright © 2012 Wenbao Zhang et al. This is an open access article distributed under the

Echinococcus granulosus infection reduces airway inflammation of mice likely through enhancing IL-10 and down-regulation of IL-5 and IL-17A

Background Cystic echinococcosis (CE) is a near cosmopolitan zoonosis caused by the larval stage of the dog tapeworm Echinococcus granulosus. E. granulosus infection induces a polarized T-helper type 2 (Th2) systematic immune response in its intermediate hosts. However, it is not known whether the infection modulates lung inflammation by regulating local immune response. In this...

Transcriptional Profiles of Cytokine/Chemokine Factors of Immune Cell-Homing to the Parasitic Lesions: A Comprehensive One-Year Course Study in the Liver of E. multilocularis-Infected Mice

Pathogenesis of chronically developing alveolar echinococcosis (AE) is characterized by a continuous, granulomatous, periparasitic infiltration of immune cells surrounding the metacestode of Echinococcus multilocularis (E.multilocularis) in the affected liver. A detailed cytokine and chemokine profile analysis of the periparasitic infiltrate in the liver has, however, not yet...

Genome-wide sequencing of small RNAs reveals a tissue-specific loss of conserved microRNA families in Echinococcus granulosus

Background MicroRNAs (miRNAs) are important post-transcriptional regulators which control growth and development in eukaryotes. The cestode Echinococcus granulosus has a complex life-cycle involving different development stages but the mechanisms underpinning this development, including the involvement of miRNAs, remain unknown. Results Using Illumina next generation sequencing...

The Echinococcus granulosus Antigen B Gene Family Comprises at Least 10 Unique Genes in Five Subclasses Which Are Differentially Expressed

Background Antigen B (EgAgB) is a major protein produced by the metacestode cyst of Echinococcus granulosus, the causative agent of cystic hydatid disease. This protein has been shown to play an important role in modulating host immune responses, although its precise biological function still remains unknown. It is generally accepted that EgAgB is comprised of a gene family of...

Inconsistent Protective Efficacy and Marked Polymorphism Limits the Value of Schistosoma japonicum Tetraspanin-2 as a Vaccine Target

Background Schistosoma mansoni tetraspanin 2 (Sm-TSP-2) has been shown to be strongly recognized by IgG1 and IgG3 antibodies from individuals putatively resistant to schistosome infection, but not chronically infected people, and to induce high levels of protection against challenge infection in the murine model of schistosomiasis. Amplification by PCR of homologous sequences...

Cloning and Characterisation of Schistosoma japonicum Insulin Receptors

Background Schistosomes depend for growth and development on host hormonal signals, which may include the insulin signalling pathway. We cloned and assessed the function of two insulin receptors from Schistosoma japonicum in order to shed light on their role in schistosome biology. Methodology/Principal Findings We isolated, from S. japonicum, insulin receptors 1 (SjIR-1) and 2...

A Pilot Study for Control of Hyperendemic Cystic Hydatid Disease in China

Background Cystic hydatid disease (CHD) is a global parasitic zoonosis caused by the dog tapeworm, Echinococcus granulosus. The disease is hyperendemic in western China because of poor economic development; limited community knowledge of CHD; widespread, small-scale household animal production; home killing of livestock; and the feeding of dogs with uncooked offal. Methodology...

SHORT REPORT: ECHINOCOCCUS GRANULOSUS FROM XINJIANG, PR CHINA: cDNAS ENCODING THE EG95 VACCINE ANTIGEN ARE EXPRESSED IN DIFFERENT LIFE CYCLE STAGES AND ARE CONSERVED IN THE ONCOSPHERE

, The Queensland Institute of Medical Research and The University of Queensland , Brisbane , Queensland 4029. Wenbao Zhang , Zhuangzhi Zhang, and Gulinul Turson, Veterinary Research Institute, Xinjiang

Vaccination of Dogs against Echinococcus granulosus the Cause of Cystic Hydatid Disease in Humans

Dogs are pivotal in Echinococcus granulosus transmission to humans, and dog vaccination provides a very practical and cost-effective prevention strategy. We vaccinated dogs with soluble native proteins isolated from protoscoleces of E. granulosus and induced significant suppression of worm growth and egg production. Accordingly, we tested for vaccine efficacy using recombinant...