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Mechanism and resistance for antimycobacterial activity of a fluoroquinophenoxazine compound

: Pamela K. Garcia, Thirunavukkarasu Annamalai, Wenjie Wang, Raven S. Bell, Duc Le, Paula Martin Pancorbo, Sabah Sikandar, Ahmed Seddek, Purushottam B. Tiwari, Methodology: Thirunavukkarasu Annamalai ... -Ching TseWriting ? original draft: Pamela K. Garcia, Thirunavukkarasu Annamalai, Fenfei Leng. Writing ? review & editing: Thirunavukkarasu Annamalai, Wenjie Wang, Raven S. Bell, Duc Le, Paula Martin

The newsvendor model revisited: the impacts of high unit holding costs on the accuracy of the classic model

Jacqueline Wenjie Wang 1 Hong Yan 2 0 Division of Business and Management, Beijing Normal University-Hong Kong Baptist University, United International College , 2000 JinTong Road, Tangjiawan, Zhuhai

Glomalin contributed more to carbon, nutrients in deeper soils, and differently associated with climates and soil properties in vertical profiles

Despite vital importance in soil conditioning and a proxy for arbuscular mycorrhizal (AMF), glomalin-related soil protein (GRSP) contribution to soil carbon and nutrients at vertical soil profiles and underlying mechanism were not well-defined yet. Thus, 360 soil samples were collected from 72 farmland 1-m soil profiles in northeastern China, and soil physiochemical properties...

The UbL-UBA Ubiquilin4 protein functions as a tumor suppressor in gastric cancer by p53-dependent and p53-independent regulation of p21

, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, ChinaShengkai Huang, Yan Li, Mei Zhao, Hong Lin, Qiao Zhang, Wenjie Wang ... , ChinaShengkai Huang, Yan Li, Mei Zhao, Hong Lin, Qiao Zhang, Wenjie Wang, Dongdong Li & Changzhi HuangDepartment of Clinical Laboratory, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences

An Adaptive Information Quantity-Based Broadcast Protocol for Safety Services in VANET

Academic Editor: Seok-Chul Kwon Copyright © 2016 Wenjie Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution

An Adaptive Information Quantity-Based Broadcast Protocol for Safety Services in VANET

Vehicle-to-vehicle communication plays a significantly important role in implementing safe and efficient road traffic. When disseminating safety messages in the network, the information quantity on safety packets changes over time and space. However, most of existing protocols view each packet the same to disseminate, preventing vehicles from collecting more recent and precise...

Lactobacillus acidophilus alleviates the inflammatory response to enterotoxigenic Escherichia coli K88 via inhibition of the NF-κB and p38 mitogen-activated protein kinase signaling pathways in piglets

Background A newly isolated L. acidophilus strain has been reported to have potential anti-inflammatory activities against lipopolysaccharide (LPS) challenge in piglet, while the details of the related inflammatory responses are limited. Here we aimed to analysis the ability of L. acidophilus to regulate inflammatory responses and to elucidate the mechanisms involved in its anti...

Identification of a six-lncRNA signature associated with recurrence of ovarian cancer

Ovarian cancer (OvCa) is the leading cause of death among all gynecological malignancies, and recurrent OvCa is almost always incurable. In this study, we developed a signature based on long non-coding RNAs (lncRNAs) associated with OvCa recurrence to facilitate personalized OvCa therapy. lncRNA expression data were extracted from GSE9891 and GSE30161. LASSO (least absolute...

Assembling Bare Au Nanoparticles at Positively Charged Templates

In-situ X-ray reflectivity (XRR) and grazing incidence X-ray small-angle scattering (GISAXS) reveal that unfunctionalized (bare) gold nanoparticles (AuNP) spontaneously adsorb to a cationic lipid template formed by a Langmuir monolayer of DPTAP (1,2-dihexadecanoyl-3-trimethylammonium-propane) at vapor/aqueous interfaces. Analysis of the XRR yields the electron density profile...

Perfluorocarbon reduces cell damage from blast injury by inhibiting signal paths of NF-κB, MAPK and Bcl-2/Bax signaling pathway in A549 cells

Background and objective Blast lung injury is a common type of blast injury and has very high mortality. Therefore, research to identify medical therapies for blast injury is important. Perfluorocarbon (PFC) is used to improve gas exchange in diseased lungs and has anti-inflammatory functions in vitro and in vivo. The aim of this study was to determine whether PFC reduces damage...

Onset of persistent pseudomonas aeruginosa infection in children with cystic fibrosis with interval censored data

Background Persistent Pseudomonas aeruginosa (PPA) infection promotes lung function deterioration in children with cystic fibrosis (CF). Although early CF diagnosis through newborn screening (NBS) has been shown to provide nutritional/growth benefit, it is unclear whether NBS lowers the risk of PPA infection and how the effect of NBS vary with age. Modeling the onset age of PPA...

Role and Variation of the Amount and Composition of Glomalin in Soil Properties in Farmland and Adjacent Plantations with Reference to a Primary Forest in North-Eastern China

The glycoprotein known as glomalin-related soil protein (GRSP) is abundantly produced on the hyphae and spores of arbuscular mycorrhizal fungi (AMF) in soil and roots. Few studies have focused on its amount, composition and associations with soil properties and possible land-use influences, although the data hints at soil rehabilitation. By choosing a primary forest soil as a non...

Effect of Reinforced Concrete Cracking on Chloride Ion Penetration

This article is to explore the effect of conditions of reinforced concrete on chloride ion penetration. The influence of the crack width and the thickness of protective layer were studied. In consideration of the randomness of concrete crack width and the fuzziness of its effect on durability, the fuzzy reliability index calculation method was adopted in this paper to calculate...

Differences in the Activities of Eight Enzymes from Ten Soil Fungi and Their Possible Influences on the Surface Structure, Functional Groups, and Element Composition of Soil Colloids

How soil fungi function in soil carbon and nutrient cycling is not well understood by using fungal enzymatic differences and their interactions with soil colloids. Eight extracellular enzymes, EEAs (chitinase, carboxymethyl cellulase, β-glucosidase, protease, acid phosphatase, polyphenol oxidase, laccase, and guaiacol oxidase) secreted by ten fungi were compared, and then the...

ON PARALLELISM OF ASCREEN HALF LIGHTLIKE SUBMANIFOLDS OF INDEFINITE COSYMPLECTIC MANIFOLDS

In this paper, we mainly study the parallelism of the second fundamental forms of ascreen half lightlike submanifolds of indefinite cosymplectic manifolds. It is proved that a half lightlike submanifold M of an indefinitecosymplectic space form (M (c), g) with semi-parallel second fundamental formh either satisfies c = 0 or is (J (Rad(T M )), T M )-mixed geodesic. Moreover,some...

On Bernstein-Type Theorems in Semi-Riemannian Warped Products

Copyright © 2013 Wenjie Wang and Ximin Liu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any

On Bernstein-Type Theorems in Semi-Riemannian Warped Products

Copyright © 2013 Wenjie Wang and Ximin Liu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any

Embryonic attenuated Wnt/β-catenin signaling defines niche location and long-term stem cell fate in hair follicle

and long-term stem cell fate in hair follicle Zijian Xu, Wenjie Wang, Kaiju Jiang, Zhou Yu, Huanwei Huang, Fengchao Wang, Bin Zhou and Ting Chen* National Institute of Biological Sciences, Beijing

A Comprehensive Analysis of Metabolomics and Transcriptomics in Cervical Cancer

Cervical cancer (CC) still remains a common and deadly malignancy among females in developing countries. More accurate and reliable diagnostic methods/biomarkers should be discovered. In this study, we performed a comprehensive analysis of metabolomics (285 samples) and transcriptomics (52 samples) on the potential diagnostic implication and metabolic characteristic description...

FR database 1.0: a resource focused on fruit development and ripening

Fruits form unique growing period in the life cycle of higher plants. They provide essential nutrients and have beneficial effects on human health. Characterizing the genes involved in fruit development and ripening is fundamental to understanding the biological process and improving horticultural crops. Although, numerous genes that have been characterized are participated in...