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Association of prenatal and childhood environment smoking exposure with puberty timing: a systematic review and meta-analysis

ObjectivesMothers who smoke during pregnancy or while their children are small were common in some populations. Epidemiological studies have tried to detect the effect of prenatal tobacco smoke (PTS), and childhood environmental tobacco smoke (ETS) on puberty timing have not shown a consensus results. We aimed to examine current evidence and estimate the associations between PTS...

Association of prenatal and childhood environment smoking exposure with puberty timing: a systematic review and meta-analysis

Mothers who smoke during pregnancy or while their children are small were common in some populations. Epidemiological studies have tried to detect the effect of prenatal tobacco smoke (PTS), and childhood environmental tobacco smoke (ETS) on puberty timing have not shown a consensus results. We aimed to examine current evidence and estimate the associations between PTS or/and ETS...

Inner Ear Hair Cell Protection in Mammals against the Noise-Induced Cochlear Damage

Li 4 Geng-lin Li 0 Department of Biotechnology, Federal Urdu University of Arts, Science and Technology, Gulshan-e-Iqbal Campus , Karachi , Pakistan 1 Key Laboratory for Developmental Genes and Human

Shifts in the fluorescence lifetime of EGFP during bacterial phagocytosis measured by phase-sensitive flow cytometry

 & Jessica P. HoustonChemistry and Biochemistry, New Mexico State University, Las Cruces, NM, 88003, USAKevin D. Houston AuthorsSearch for Wenyan Li in:Nature Research journals • PubMed • Google ScholarSearch

Adenovirus Vectors Target Several Cell Subtypes of Mammalian Inner Ear In Vivo

Health (R01 DC006908). Yilai Shu, Yong Tao, and Wenyan Li were supported by the Frederick and Ines Yeatts Hair Cell Regeneration Grant and Yilai Shu by the National Nature Science Foundation of China

Adenovirus Vectors Target Several Cell Subtypes of Mammalian Inner Ear In Vivo

Health (R01 DC006908). Yilai Shu, Yong Tao, and Wenyan Li were supported by the Frederick and Ines Yeatts Hair Cell Regeneration Grant and Yilai Shu by the National Nature Science Foundation of China

Defective thymic output in WAS patients is associated with abnormal actin organization

Wiskott-Aldrich syndrome protein (WASp) is a key regulator of the actin cytoskeleton. Defective T - cell function is a major cause for immune deficiency in Wiskott-Aldrich syndrome (WAS) patients. T cells originate in the bone marrow and develop in the thymus, and then migrate to peripheral tissues. TCR excision circles (TRECs) present in thymic output cells stably, which is used...

Liouville-type theorem for some nonlinear systems in a half-space

In this paper we consider the following Hardy-Littlewood-Sobolev (HLS)-type system of nonlinear equations in the half-space R + n : u ( x ) = ∫ R + n ( 1 | x − y | n − α − 1 | x ∗ − y | n − α ) v q ( y ) d y , v ( x ) = ∫ R + n ( 1 | x − y | n − α − 1 | x ∗ − y | n − α ) u p ( y ) d y , where p , q > 1 and x ∗ is the reflection of x about the boundary { x n = 0 } . By using the...

Preparation of SiC powders by carbothermal reduction with bamboo charcoal as renewable carbon source

Bamboo charcoal was expected to be a renewable carbon source for carbide materials in carbothermal reduction because of its superior characteristics. SiC powders with characteristic shapes were fabricated by carbothermal reduction with industrial silica sol and bamboo charcoal particles as silicon and carbon sources respectively, and the effects of reacting temperature and time...

Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration

Unlike mammals, the non-mammalian vertebrate inner ear can regenerate the sensory cells, hair cells, either spontaneously or through induction after hair cell loss, leading to hearing recovery. The mechanisms underlying the regeneration are poorly understood. By microarray analysis on a chick model, we show that chick hair cell regeneration involves the activation of...

NLRP3 inflammasome activation contributes to Listeria monocytogenes-induced animal pregnancy failure

Center of Veterinary Biotechnology , Baoding 071000 , China 2 Wenyan Li and Yumei Chang should be considered as the first authors 3 Department of Medicine, School of Medicine, University of California San

Disrupting the Interaction between Retinoblastoma Protein and Raf-1 Leads to Defects in Progenitor Cell Proliferation and Survival during Early Inner Ear Development

Development Wenyan Li Shan Sun Yan Chen Huiqian Yu Zheng-Yi Chen Huawei Li Maria Cristina Vinci, Cardiological Center Monzino, Italy The retinoblastoma protein (pRb) is required for cell-cycle exit of

Phylogenetic analysis, structural evolution and functional divergence of the 12-oxo-phytodienoate acid reductase gene family in plants

Background The 12-oxo-phytodienoic acid reductases (OPRs) are enzymes that catalyze the reduction of double-bonds in α, β-unsaturated aldehydes or ketones and are part of the octadecanoid pathway that converts linolenic acid to jasmonic acid. In plants, OPRs belong to the old yellow enzyme family and form multigene families. Although discoveries about this family in Arabidopsis...

Adult-onset Alexander disease, associated with a mutation in an alternative GFAP transcript, may be phenotypically modulated by a non-neutral HDAC6 variant

Melchionda 0 Mingyan Fang Hairong Wang Valeria Fugnanesi Michela Morbin Xuanzhu Liu Wenyan Li Isabella Ceccherini Laura Farina Mario Savoiardo Pio D'Adamo Jianguo Zhang Alfredo Costa Sabrina Ravaglia Daniele

Evidence for X-Chromosomal Schizophrenia Associated with microRNA Alterations

Background Schizophrenia is a severe disabling brain disease affecting about 1% of the population. Individual microRNAs (miRNAs) affect moderate downregulation of gene expression. In addition, components required for miRNA processing and/or function have also been implicated in X-linked mental retardation, neurological and neoplastic diseases, pointing to the wide ranging...

Missense Mutations in the MEFV Gene Are Associated with Fibromyalgia Syndrome and Correlate with Elevated IL-1β Plasma Levels

Background Fibromyalgia syndrome (FMS), a common, chronic, widespread musculoskeletal pain disorder found in 2% of the general population and with a preponderance of 85% in females, has both genetic and environmental contributions. Patients and their parents have high plasma levels of the chemokines MCP-1 and eotaxin, providing evidence for both a genetic and an immunological...

Most spontaneous tumors in a mouse model of Li-Fraumeni syndrome do not have a mutator phenotype

Mutations are the substrate of cancer. Yet, little is known about the degree and nature of mutations in tumors because measurement of mutation load in tumors and normal tissues was generally not possible until the advent of transgenic mouse mutation detection systems. Herein, we present the first analysis of mutation frequency and pattern in thymic tumors from a mouse model of Li...