cancer (BIOPEX-study) Gijsbert D Musters 0 Willem A Bemelman 0 Robbert JI Bosker 9 Jacobus WA Burger 8 Peter van Duijvendijk 14 Boudewijn van Etten 13 Anna AW van Geloven 12 Eelco JR de Graaf 11
Primary perineal wound closure after conventional abdominoperineal resection (cAPR) for rectal cancer has been the standard of care for many years. Since the introduction of neo-adjuvant radiotherapy and the extralevator APR (eAPR), oncological outcome has been improved, but at the cost of increased rates of perineal wound healing problems and perineal hernia. This has...
Background Low transsphincteric fistulas less than 1/3 of the sphincter complex are easy to treat by fistulotomy with a high success rate. High transsphincteric fistulas remain a surgical challenge. Various surgical procedures are available, but recurrence rates of these techniques are disappointingly high. The mucosal flap advancement is considered the gold standard for the...
Low transsphincteric fistulas less than 1/3 of the sphincter complex are easy to treat by fistulotomy with a high success rate. High transsphincteric fistulas remain a surgical challenge. Various surgical procedures are available, but recurrence rates of these techniques are disappointingly high. The mucosal flap advancement is considered the gold standard for the treatment of...
Backround Diverticulosis is a common disease in the western society with an incidence of 33–66%. 10–25% of these patients will develop diverticulitis. In order to prevent a high-risk acute operation it is advised to perform elective sigmoid resection after two episodes of diverticulitis in the elderly patient or after one episode in the younger (< 50 years) patient. Open sigmoid...
Diverticulosis is a common disease in the western society with an incidence of 33–66%. 10–25% of these patients will develop diverticulitis. In order to prevent a high-risk acute operation it is advised to perform elective sigmoid resection after two episodes of diverticulitis in the elderly patient or after one episode in the younger (< 50 years) patient. Open sigmoid resection...
Negpodiev Marcel GW Dijkgraaf Geert RAM D'Haens Willem A Bemelman 0 0 Department of Surgery, Academic Medical Centre , PO Box 22660, 1100 DD Amsterdam , The Netherlands Background: Over the past 20 years
Over the past 20 years evidence has accumulated confirming the immunomodulatory role of the appendix in ulcerative colitis (UC). This led to the idea that appendectomy might alter the clinical course of established UC. The objective of this body of research is to evaluate the short-term and medium-term efficacy of appendectomy to maintain remission in patients with UC, and to...
Jeanin E van Hooft 10 Willem A Bemelman 9 Ronald Breumelhof 8 Peter D Siersema 15 Philip M Kruyt 14 Klaas van der Linde 13 Roeland A Veenendaal 12 Marie-Louise Verhulst 17 Andreas W Marinelli
Acute left-sided colonic obstruction is most often caused by malignancy and the surgical treatment is associated with a high mortality and morbidity rate. Moreover, these operated patients end up with a temporary or permanent stoma. Initial insertion of an enteral stent to decompress the obstructed colon, allowing for surgery to be performed electively, is gaining popularity. In...
Doornebosch 11 Annekatrien CTM Depla 12 Miranda F Ernst 13 Ivo P van Munster 14 Ignace HJT de Hingh 15 Erik J Schoon 16 Willem A Bemelman 17 Paul Fockens 20 Evelien Dekker 20 0 Dept of Gastroenterology
Recent non-randomized studies suggest that extended endoscopic mucosal resection (EMR) is equally effective in removing large rectal adenomas as transanal endoscopic microsurgery (TEM). If equally effective, EMR might be a more cost-effective approach as this strategy does not require expensive equipment, general anesthesia and hospital admission. Furthermore, EMR appears to be...
12 Muriel AM Siepel 13 Anna AW van Geloven 10 Jan-Willem Juttmann 10 Wilfred Clevers 11 Willem A Bemelman 3 0 Department of clinical epidemiology and biostatistics, Academic Medical Center
Donald L van der Peet Marc JPM Govaert Alexander F Engel Johannes B Reitsma Willem A Bemelman 1 Dutch Diverticular Disease Collaborative Study Group 1 0 Department of Surgery, Erasmus Medical Centre
Emma J Eshuis Willem A Bemelman Ad A van Bodegraven Mirjam AG Sprangers Patrick MM Bossuyt AW Rogier Crolla Djuna L Cahen Liekele E Oostenbrug Meindert N Sosef Annet MCJ Voorburg Paul HP Davids C ... , Zaans Medical Center, Zaandam, The Netherlands and 54Department of Surgery, Zaans Medical Center, Zaandam, The Netherlands Email: Emma J Eshuis* - ; Willem A Bemelman - ; Ad A van Bodegraven - ; Mirjam AG
With the availability of infliximab, nowadays recurrent Crohn's disease, defined as disease refractory to immunomodulatory agents that has been treated with steroids, is generally treated with infliximab. Infliximab is an effective but expensive treatment and once started it is unclear when therapy can be discontinued. Surgical resection has been the golden standard in recurrent...
