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Guidelines and recommendations for ensuring Good Epidemiological Practice (GEP): a guideline developed by the German Society for Epidemiology

, as well as research institutes and funding bodies. KeywordsGuideline Recommendation Epidemiologic methods Professional practice Expert consensus Research practice  Wolfgang Hoffmann and Ute Latza ... Greiser, Hans-Werner Hense, Wolfgang Hoffmann, Rolf Holle, Ingeborg Jahn, Karl-Heinz Jöckel, Wolf Kirschner, Thomas Kohlmann, Bärbel-Maria Kurth (former Bärbel-Maria Bellach), Ute Latza, Angela Liese

Toolbox for Research, or how to facilitate a central data management in small-scale research projects

In most research projects budget, staff and IT infrastructures are limiting resources. Especially for small-scale registries and cohort studies professional IT support and commercial electronic data capture systems are too expensive. Consequently, these projects use simple local approaches (e.g. Excel) for data capture instead of a central data management including web-based data...

Cost of diagnosing dementia in a German memory clinic

Background Little is known about diagnostic work-ups or the costs of diagnosing dementia in specialized care. Here, we analyzed the costs of diagnosing dementia according to specific dementia disorders. Methods A prospective descriptive design was used to analyze the cost of diagnosing dementia for 120 patients with suspected dementia at a German memory clinic. The duration of...

Potential and restrictions of photocentrifugation for determining the emulsion stability of melted spreadable processed cheese

A previous study had shown that the method of photocentrifugation could be adapted to monitor emulsion stability of melted spreadable processed cheese (PC) with low content of emulsifying salts (ES). The present study continued the experiments with higher ES content exploring the potential and restrictions of this new approach. The PC containing 40% fat in dry matter and 1.0 or 1...

Accessibility of general practitioners and selected specialist physicians by car and by public transport in a rural region of Germany

Background The accessibility of medical care facilities in sparsely populated rural regions is relevant especially for elderly people which often represent a large segment of the population in such regions. Elderly people have higher morbidity risks and a higher demand for medical care. Although travelling with private cars is the dominating traffic mode in rural regions...

Association of Glioblastoma Multiforme Stem Cell Characteristics, Differentiation, and Microglia Marker Genes with Patient Survival

Plantera,2 Silke Vogelgesang,3 Kerstin Weitmann,4 Carolin Seifert,1,2 Matthias A. Fink,1,2 Sascha Marx,1 Angela Bialke,5 Chitra Venugopal,6 Sheila K. Singh,6 Wolfgang Hoffmann,4 Bernhard H. Rauch,1 and Henry

Systematic, early identification of dementia and dementia care management are highly appreciated by general physicians in primary care – results within a cluster-randomized-controlled trial (DelpHi)

cluster-randomized-controlled trial (DelpHi) Wolfgang Hoffmann 0 1 0 Department of epidemiology of Health care and community Health, institute for community Medicine, University of greifswald , greifswald

Editorial

, 17487 Greifswald , Germany Ulrike Siewert & Wolfgang Hoffmann - The current issue of the Journal of Public Health highlights different aspects and determinants of health, prevention and health care

Not Just the Demographic Change – The Impact of Trends in Risk Factor Prevalences on the Prediction of Future Cases of Myocardial Infarction

Background Previous predictions of population morbidity consider demographic changes only. To model future morbidity, however, changes in prevalences of risk factors should be considered. We calculated the number of incident cases of first myocardial infarction (MI) in Mecklenburg-Western Pomerania in 2017 considering the effects of demographic changes and trends in the...

A workflow-driven approach to integrate generic software modules in a Trusted Third Party

Background Cohort studies and registries rely on massive amounts of personal medical data. Therefore, data protection and information security as well as ethical aspects gain in importance and need to be considered as early as possible during the establishment of a study. Resulting legal and ethical obligations require a precise implementation of appropriate technical and...

Influence of reproductive history and exogenous hormone use on prevalence and frequency of circulating t(14;18)-positive cells in a population-based cross-sectional study

Purpose The t(14;18) translocation might represent an intermediate step in the pathogenesis of follicular lymphoma (FL), one of the most common subtypes of non-Hodgkin lymphoma. Circulating t(14;18)-positive cells can also be detected in 30–60 % of healthy individuals at low frequencies. Some studies found a negative association between reproductive factors or use of menopausal...

Associations of Motor Developmental Risks with the Socioeconomic Status of Preschool Children in North-Eastern Germany

Aims. The study is part of the pilot project “children in preschools” and aims to detect developmental risks of preschool children in the context of their socioeconomic status (SES) as a base to initiate individual intervention strategies. Methods. The “Dortmund Developmental Screening for the Kindergarten” was used in 12 preschools in Mecklenburg-Western Pomerania (MWP) to...

Tecla: a telephone- and text-message based telemedical concept for patients with severe mental health disorders – study protocol for a controlled, randomized, study

Background Severe mental disorders like psychotic disorders including schizophrenia and schizoaffective disorders have a 12-month-prevalence of 2.6, bipolar disorders of 1.5 % in Germany. The relapse risk is high; so many patients need intensive monitoring and lifelong treatment. A high medication adherence is essential for a successful treatment. But in practice, medication...

Antidementia drug treatment in dementia networks in Germany: use rates and factors associated with treatment use

Background Dementia networks in Germany constitute a specialised setting for integrated dementia care and have shown benefits on relevant outcomes, including those of drug treatment. National guidelines recommend treatment with acetylcholinesterase inhibitors (donepezil, galantamine, rivastigmine) or the N-Methyl-D-Aspartate antagonist (memantine) to reduce cognitive symptoms...

Influence of Age, Sex and Calendar Year on Lifetime Accumulated Red Bone Marrow Dose from Diagnostic Radiation Exposure

Our aim is to evaluate the relevance of different factors influencing lifetime accumulated red bone marrow dose, such as calendar year, age and sex. The lifetime dose was estimated for controls interviewed in person (N = 2811, 37.5% women) of the population-based representative Northern Germany Leukemia and Lymphoma Study. Data were assessed in standardized computer-assisted...

Chronic diseases in pregnant women: prevalence and birth outcomes based on the SNiP-study

Background The subject of “pregnancy and disease” is of particular importance for maternal well-being and neonatal outcomes. The international literature has focused on acute diseases during pregnancy; however, there are only a few studies investigating chronic diseases in pregnant women. The focus of this study is on diseases of women in childbearing age that are not related to...

Improving hospital hygiene to reduce the impact of multidrug-resistant organisms in health care–a prospective controlled multicenter study

Jens Piegsa Christian Schäfer Nils-Olaf Hübner Florian Wilke Susanne Reuter Georg Engel Ralf Ewert Franziska Claus Claudia Hübner Walter Ried Steffen Flessa Axel Kramer Wolfgang Hoffmann Background

Medication management for people with dementia in primary care: description of implementation in the DelpHi study

Background As the population ages, the relative and absolute number of age-associated diseases such as dementia will increase. Evaluation of the suitability and intake of medication and pharmacological treatment is an important aspect of care for people with dementia, especially if they live at home. Regular medication reviews and systematic cooperation between physicians and...

Prevalence and determinants of controlled hypertension in a German population cohort

Wolfgang Hoffmann 1 0 Equal contributors 1 University Medicine Greifswald, Institute for Community Medicine Ellernholzstrasse 1-2 , 17487, Greifswald , Germany 2 German Center for Neurodegenerative Diseases