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Search: authors:"Wolfram Miekisch"

9 papers found.
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Exploring the potential of NTME/GC-MS, in the establishment of urinary volatomic profiles. Lung cancer patients as case study

-Figueira in:Nature Research journals • PubMed • Google Scholar Search for Jorge Pereira in:Nature Research journals • PubMed • Google Scholar Search for Wolfram Miekisch in:Nature Research journals ... experimental parameters, GC-MS parameters and data analysis. José S. Câmara conceived the experiment(s); Wolfram Miekisch selected/optimized NTD packing materials; Priscilla Porto-Figueira, Jorge Pereira

Comparative analysis of volatile organic compounds for the classification and identification of mycobacterial species

involved members of the ROMBAT breath research team in Rostock. Author Contributions Conceptualization: Jochen Schubert, Wolfram Miekisch, Heike KoÈhler. Data curation: Anne KuÈntzel, Peter Oertel, Sina ... Fischer, Andreas Bergmann, Phillip Trefz. Formal analysis: Anne KuÈntzel, Phillip Trefz. Funding acquisition: Jochen Schubert, Wolfram Miekisch, Petra Reinhold, Heike KoÈhler. Investigation: Anne KuÈntzel

Exhaled volatile substances mirror clinical conditions in pediatric chronic kidney disease

Dagmar-Christiane Fischer 1 Wolfram Miekisch 0 1 0 Department of Anesthesiology and Intensive Care Medicine, Rostock Medical Breath Research Analytics and Technologies (ROMBAT), University Medicine Rostock

Erratum to: Evaluation of needle trap micro-extraction and automatic alveolar sampling for point-of-care breath analysis

Wolfram Miekisch 0 ) Department of Anaesthesia and Intensive Care, University of Rostock , Schillingallee 35, 18057 Rostock , Germany The authors should like to call your attention to the fact that

In Vivo Volatile Organic Compound Signatures of Mycobacterium avium subsp. paratuberculosis

Mycobacterium avium ssp. paratuberculosis (MAP) is the causative agent of a chronic enteric disease of ruminants. Available diagnostic tests are complex and slow. In vitro, volatile organic compound (VOC) patterns emitted from MAP cultures mirrored bacterial growth and enabled distinction of different strains. This study was intended to determine VOCs in vivo in the controlled...

Volatile Emissions from Mycobacterium avium subsp. paratuberculosis Mirror Bacterial Growth and Enable Distinction of Different Strains

Control of paratuberculosis in livestock is hampered by the low sensitivity of established direct and indirect diagnostic methods. Like other bacteria, Mycobacterium avium subsp. paratuberculosis (MAP) emits volatile organic compounds (VOCs). Differences of VOC patterns in breath and feces of infected and not infected animals were described in first pilot experiments but detailed...

Monitoring of oxidative and metabolic stress during cardiac surgery by means of breath biomarkers: an observational study

Background Volatile breath biomarkers provide a non-invasive window to observe physiological and pathological processes in the body. This study was intended to assess the impact of heart surgery with extracorporeal circulation (ECC) onto breath biomarker profiles. Special attention was attributed to oxidative or metabolic stress during surgery and extracorporeal circulation...

Release of volatile organic compounds (VOCs) from the lung cancer cell line CALU-1 in vitro

Background The aim of this work was to confirm the existence of volatile organic compounds (VOCs) specifically released or consumed by lung cancer cells. Methods 50 million cells of the human non-small cell lung cancer (NSCLC) cell line CALU-1 were incubated in a sealed fermenter for 4 h or over night (18 hours). Then air samples from the headspace of the culture vessel were...

Noninvasive detection of lung cancer by analysis of exhaled breath

Background Lung cancer is one of the leading causes of death in Europe and the western world. At present, diagnosis of lung cancer very often happens late in the course of the disease since inexpensive, non-invasive and sufficiently sensitive and specific screening methods are not available. Even though the CT diagnostic methods are good, it must be assured that "screening...