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Ultra-low noise optical injection locking amplifier with AOM-based coherent detection scheme

, 201800, ChinaZitong Feng, Fei Yang, Xi Zhang, Dijun Chen, Fang Wei, Yanguang Sun & Haiwen CaiKey Laboratory for Quantum Optics, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Science ... , Shanghai, 201800, ChinaNan Cheng & Youzhen GuiUniversity of the Chinese Academy of Sciences, Beijing, 100049, ChinaZitong Feng & Xi Zhang AuthorsSearch for Zitong Feng in:Nature Research journals • PubMed

Invasive meningococcal disease in Shanghai, China from 1950 to 2016: implications for serogroup B vaccine implementation

AffiliationsDepartment of Microbiology and Division of Infectious Diseases, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, ChinaMingliang Chen, Chi Zhang, Tian Tan, Jian Chen, Xi Zhang & Min ... Scholar Search for Xi Zhang in:Nature Research journals • PubMed • Google Scholar Search for Min Chen in:Nature Research journals • PubMed • Google Scholar Search for Martin C. J. Maiden in:Nature

The Hsp70 inhibitor 2-phenylethynesulfonamide inhibits replication and carcinogenicity of Epstein–Barr virus by inhibiting the molecular chaperone function of Hsp70

Epstein–Barr virus (EBV) can infect cells in latent and lytic period and cause serious disease. Epstein–Barr virus nuclear antigen 1 (EBNA1) is essential for the maintenance of the EBV DNA episome, replication and transcription. 2-phenylethynesulfonamide (PES) is a small molecular inhibitor of Heat shock protein 70 (Hsp70), which can interact with Hsp70 and disrupts its...

Geometric isotope effect of deuteration in a hydrogen-bonded host–guest crystal

Deuteration of a hydrogen bond by replacing protium (H) with deuterium (D) can cause geometric changes in the hydrogen bond, known as the geometric H/D isotope effect (GIE). Understanding the GIEs on global structures and bulk properties is of great importance to study structure–property relationships of hydrogen-bonded systems. Here, we report a hydrogen-bonded host–guest...

Antimicrobial cationic polymers: from structural design to functional control

University in 2015. He joined Professor Xi Zhang?s group as a PhD student in Department of Chemistry at Tsinghua University since August 2015. Now, his research interests are focused on the supramolecular ... 2017, he joined Professor Xi Zhang?s group at Tsinghua University as a research assistant, where he focused on supramolecular polymers and supra-amphiphiles. From August 2017, he started pursuing PhD

Potential of mean force between oppositely charged nanoparticles: A comprehensive comparison between Poisson–Boltzmann theory and Monte Carlo simulations

Ion-mediated interactions between like-charged polyelectrolytes have been paid much attention, and the Poisson–Boltzmann (PB) theory has been shown to fail in qualitatively predicting multivalent ion-mediated like-charge attraction. However, inadequate attention has been paid to the ion-mediated interactions between oppositely charged polyelectrolytes. In this work, the...

Root exudate metabolites drive plant-soil feedbacks on growth and defense by shaping the rhizosphere microbiota

, SwitzerlandLingfei Hu, Christelle A. M. Robert, Xi Zhang, Meng Ye, Beibei Li, Daniele Manzo, Klaus Schlaeppi & Matthias ErbDivision of Agroecology and Environment, Agroscope, 8046, Zürich, SwitzerlandSelma Cadot ... journals • PubMed • Google Scholar Search for Xi Zhang in:Nature Research journals • PubMed • Google Scholar Search for Meng Ye in:Nature Research journals • PubMed • Google Scholar Search for Beibei Li

New Insights into PI3K Inhibitor Design using X-ray Structures of PI3Kα Complexed with a Potent Lead Compound

Phosphatidylinositol 3-kinase α is an attractive target to potentially treat a range of cancers. Herein, we described the evolution of a reported PI3K inhibitor into a moderate PI3Kα inhibitor with a low molecular weight. We used X-ray crystallography to describe the accurate binding mode of the compound YXY-4F. A comparison of the p110α–YXY-4F and apo p110α complexes showed that...

Hydrogen-bond potential for ice VIII-X phase transition

, ChinaXi ZhangSchool of Physics and Astronomy, the University of Manchester, Manchester, M13 9PL, UKShun Chen & Jichen Li AuthorsSearch for Xi Zhang in:Nature Research journals • PubMed • Google ... interests The authors declare no competing financial interests. Corresponding authors Correspondence to Xi Zhang or Jichen Li. Supplementary information PDF files1.Supplementary Information Rights

Decreased Triple Network Connectivity in Patients with Recent Onset Post-Traumatic Stress Disorder after a Single Prolonged Trauma Exposure

Lihong Li Xi Zhang Hongbing Lu Hong Yin OPEN Published: xx xx xxxx The triple network model provides a common framework for understanding affective and neurocognitive dysfunctions across multiple

Effects of NRG1 Polymorphisms on Hirschsprung’s Disease Susceptibility: A Meta-analysis

Substantial resources have been devoted to evaluate the relationship between NRG1 variants rs7835688 and rs16879552 and Hirschsprung’s Disease (HSCR) but no consistency exists. This meta-analysis aimed to assess the association between the two SNPs and HSCR. PubMed, EMBASE, and Chinese Biological Medicine databases were searched for studies potentially eligible up to March, 2017...

Optimal donor for severe aplastic anemia patient requiring allogeneic hematopoietic stem cell transplantation: A large-sample study from China

HLA-haploidentical hematopoietic stem cell transplantation (HSCT) may be an option for severe aplastic anemia (SAA) patients. However, to date, no large-sample studies have been performed to determine which types of SAA patients are suitable for HLA-haploidentical HSCT. We retrospectively studied 189 consecutive patients with SAA who underwent HLA-identical or HLA-haploidentical...

Plumbagin suppresses chronic periodontitis in rats via down-regulation of TNF-α, IL-1β and IL-6 expression

in vitro results. Author contribution Xin-yi ZHENG, Er-yi LU, Ting-yu WANG and Li YU designed research; Xin-yi ZHENG, Chuan-yuan MAO, Han QIAO and Xi ZHANG performed research; Ting-yu WANG and Li ... • PubMed • Google ScholarSearch for Xi Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Li Yu in:Nature Research journals • PubMed • Google ScholarSearch for Ting-yu Wang in:Nature

Climates on incidence of childhood type 1 diabetes mellitus in 72 countries

statistical analyses of the data. Wei Ling, Yan-hong Pan, Li-jun Geng, and Jian-long Xiao analyzed and interpreted the data. Xiao-Xi Zhang and Hai-Lu Zhao designed the study, and revised the submission. All

A blockade of PI3Kγ signaling effectively mitigates angiotensin II-induced renal injury and fibrosis in a mouse model

, Yunfeng Xia, Xi Zhang, Liqun Chen, Chen Zhao, Shifeng Huang, Jiayan Lei, Yixiao Feng, Wei Liu & Hua GanMolecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The ... for Xi Zhang in:Nature Research journals • PubMed • Google Scholar Search for Liqun Chen in:Nature Research journals • PubMed • Google Scholar Search for Shujuan Yan in:Nature Research journals

RanBP9/TSSC3 complex cooperates to suppress anoikis resistance and metastasis via inhibiting Src-mediated Akt signaling in osteosarcoma

Suppression of anoikis is a prerequisite for tumor cell metastasis, which is correlated with chemoresistance and poor prognosis. We characterized a novel interaction between RanBP9 SPRY domain and TSSC3 PH domain by which RanBP9/TSSC3 complex exerts transcription and post-translation regulation in osteosarcoma. RanBP9/TSSC3 complex was inversely correlated with a highly anoikis...

Electric-field-induced Spontaneous Magnetization and Phase Transitions in Zigzag Boron Nitride Nanotubes

We demonstrate an alternative scheme for realizing spin polarizations in semiconductor nanostructures by an all-electric way. The electronic and magnetic properties of the model system, zigzag pristine boron nitride nanotubes (BNNTs), are investigated under a transverse electric field (E) through spin-polarized density functional theory calculations. As E increases, the band gap...

Potential of mean force between like-charged nanoparticles: Many-body effect

 & Zhi-Jie TanDepartment of Physics, School of Physics & Information Engineering, Jianghan University, Wuhan 430056, ChinaXiao-Long Zhu AuthorsSearch for Xi Zhang in:Nature Research journals • PubMed

Aerosol influence on energy balance of the middle atmosphere of Jupiter

Sciences, California Institute of Technology, Pasadena, California 91125, USAYuk L. Yung AuthorsSearch for Xi Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Robert A. West in:Nature ... authors declare no competing financial interests. Corresponding author Correspondence to Xi Zhang. Rights and permissions This work is licensed under a Creative Commons Attribution 4.0 International