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Endothelial microparticles are increased in congenital heart diseases and contribute to endothelial dysfunction

Background We previously demonstrated that endothelial microparticles (EMPs) are increased in mitral valve diseases and impair valvular endothelial cell function. Perioperative systemic inflammation is an important risk factor and complication of cardiac surgery. In this study, we investigate whether EMPs increase in congenital heart diseases to promote inflammation and...

Simvastatin prevents alveolar bone loss in an experimental rat model of periodontitis after ovariectomy

Background Periodontitis is an inflammatory disease characterized by the loss of connective tissue and alveolar bone. There is an increasing evidence that periodontitis is associated with a number of chronic disease, including osteoporosis. Periodontitis and osteoporosis are both bone destructive diseases and of high prevalence in adult population. Osteoporosis could increase...

Simvastatin prevents alveolar bone loss in an experimental rat model of periodontitis after ovariectomy

Periodontitis is an inflammatory disease characterized by the loss of connective tissue and alveolar bone. There is an increasing evidence that periodontitis is associated with a number of chronic disease, including osteoporosis. Periodontitis and osteoporosis are both bone destructive diseases and of high prevalence in adult population. Osteoporosis could increase some...

Overexpression of FoxM1 is associated with tumor progression in patients with clear cell renal cell carcinoma

Xiao-Ning Wang Guo-Xi Zhang Yuan-Hu Yuan Geng-Qing Wu Jun Yang Yu-Ting Wu Hui Xu Fo-Lin Liu Min Liu 0 Equal contributors Department of Urology, First Affiliated Hospital of Gannan Medical University , No