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Comparative genomics of parasitic silkworm microsporidia reveal an association between genome expansion and host adaptation

Background Microsporidian Nosema bombycis has received much attention because the pébrine disease of domesticated silkworms results in great economic losses in the silkworm industry. So far, no effective treatment could be found for pébrine. Compared to other known Nosema parasites, N. bombycis can unusually parasitize a broad range of hosts. To gain some insights into the...

CAERUS: Predicting CAncER oUtcomeS Using Relationship between Protein Structural Information, Protein Networks, Gene Expression Data, and Mutation Data

, Gene Expression Data, and Mutation Data Kelvin Xi Zhang 0 B. F. Francis Ouellette 0 John Quackenbush, Dana-Farber Cancer Institute, United States of America 0 1 Graduate Program in Bioinformatics

Pandora, a PAthway and Network DiscOveRy Approach based on common biological evidence

Kelvin Xi Zhang 0 1 B. F. Francis Ouellette 0 Associate Editor: John Quackenbush 0 Ontario Institute for Cancer Research, MaRS Centre , South Tower, 101 College Street , Toronto , Ontario, M5G 0A3