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Investigation and genome-wide association study for Fusarium crown rot resistance in Chinese common wheat

Fusarium crown rot (FCR) is a severe and chronic disease in common wheat and is able to cause serious yield loss and health problems to human and livestock. Here, 234 Chinese wheat cultivars were evaluated in four greenhouse experiments for FCR resistance and genome-wide association studies (GWAS) were performed using the wheat 660 K genotyping assay. The results indicated that...

New species and records of Pyxine (Caliciaceae) in China

of Pyxine in China. eol>China; lichenised fungi; new species; phylogeny - Copyright Mei-Xia Yang et al. This is an open access article distributed under the terms of the Creative Commons Attribution

Cigarette smoke-induced RANKL expression enhances MMP-9 production by alveolar macrophages

Cigarette smoke-induced RANKL expression enhances MMP-9 production by alveolar macrophages Lu Zhou,1 Yanqing Le,1 Jieyu Tian,2 Xia Yang,2 Rong Jin,3 Xiaoyan Gai,1 Yongchang Sun1 1Department of

Single cell molecular alterations reveal target cells and pathways of concussive brain injury

The complex neuropathology of traumatic brain injury (TBI) is difficult to dissect, given the convoluted cytoarchitecture of affected brain regions such as the hippocampus. Hippocampal dysfunction during TBI results in cognitive decline that may escalate to other neurological disorders, the molecular basis of which is hidden in the genomic programs of individual cells. Using the...

Association of low skeletal muscle index with increased systematic inflammatory responses and interferon γ-induced protein 10 levels in patients with colon cancer

Association of low skeletal muscle index with increased systematic inflammatory responses and interferon gamma-induced protein 10 levels in patients with colon cancer Wen-Zhuo He,1,* Qiu-Xia Yang,2 ... Weinberg Peer reviewer comments 3 Editor who approved publication: Professor Nakshatri Wen-Zhuo He,1,* Qiu-Xia Yang,2,* Jin-Ye Xie,3,* Peng-Fei Kong,1 Wan-Ming Hu,4 Lin Yang,1 Yuan

Synthesis of the Sparse Uniform-Amplitude Concentric Ring Transmitting Array for Optimal Microwave Power Transmission

Zhou 0 Xue-Xia Yang 0 Sajjad Rahim 0 Ikmo Park 0 Shanghai Institute of Advanced Communication and Data Science, Key laboratory of Specialty Fiber Optics and Optical Access Networks, Joint International

Prognostic ability of cystatin C and homocysteine plasma levels for long-term outcomes in very old acute myocardial infarction patients

Prognostic ability of cystatin C and homocysteine plasma levels for long-term outcomes in very old acute myocardial infarction patients Zhenhong Fu,1,* Xia Yang,1,* Mingzhi Shen,2,* Hao Xue,1,* Geng

Decreased expression of peroxisome proliferator-activated receptor alpha indicates unfavorable outcomes in hepatocellular carcinoma

Decreased expression of peroxisome proliferator-activated receptor alpha indicates unfavorable outcomes in hepatocellular carcinoma Yong-bo Xiao,1,2,* Shao-hang Cai,1,2,* Li-li Liu,1,2 Xia Yang,1,2

Pigment Epithelium-Derived Factor Plays a Role in Alzheimer’s Disease by Negatively Regulating Aβ42

Alzheimer’s disease (AD) is the most common cause of dementia. Pigment epithelium-derived factor (PEDF), a unique neurotrophic protein, decreases with aging. Previous reports have conflicted regarding whether the PEDF concentration is altered in AD patients. In addition, the effect of PEDF on AD has not been documented. Here, we tested serum samples of 31 AD patients and 271...

Galantamine improves cognition, hippocampal inflammation, and synaptic plasticity impairments induced by lipopolysaccharide in mice

Neuroinflammation plays an important role in the onset and progression of neurodegenerative diseases such as Alzheimer’s disease. Lipopolysaccharide (LPS, endotoxin) levels are higher in the brains of Alzheimer’s disease patients and are associated with neuroinflammation and cognitive decline, while neural cholinergic signaling controls inflammation. This study aimed to examine...

Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes

L-ascorbic acid (Vitamin C) can enhance the meiotic maturation and developmental competence of porcine oocytes, but the underlying molecular mechanism remains obscure. Here we show the role of ascorbic acid in regulating epigenetic status of both nucleic acids and chromatin to promote oocyte maturation and development in pigs. Supplementation of 250 μM L-ascorbic acid 2-phosphate...

p66Shc Mediates Mitochondrial Dysfunction Dependent on PKC Activation in Airway Epithelial Cells Induced by Cigarette Smoke

Airway epithelial mitochondrial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). The p66Shc adaptor protein is a newly recognized mediator of mitochondrial dysfunction. However, little is known about the effect of p66Shc on airway epithelial damage in the development of COPD. The aim of the present study is to investigate the roles...

p66Shc Mediates Mitochondrial Dysfunction Dependent on PKC Activation in Airway Epithelial Cells Induced by Cigarette Smoke

Airway epithelial mitochondrial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). The p66Shc adaptor protein is a newly recognized mediator of mitochondrial dysfunction. However, little is known about the effect of p66Shc on airway epithelial damage in the development of COPD. The aim of the present study is to investigate the roles...

The clinical implication of serum cyclophilin A in patients with chronic obstructive pulmonary disease

The clinical implication of serum cyclophilin A in patients with chronic obstructive pulmonary disease Ming Zhang,1 Jingjing Tang,1 Jiafeng Yin,2 Xiaoying Wang,3 Xiangli Feng,1 Xia Yang,1 Hu Shan,1

Critical effects of long non-coding RNA on fibrosis diseases

The expression or dysfunction of long non-coding RNAs (lncRNAs) is closely related to various hereditary diseases, autoimmune diseases, metabolic diseases and tumors. LncRNAs were also recently recognized as functional regulators of fibrosis, which is a secondary process in many of these diseases and a primary pathology in fibrosis diseases. We review the latest findings on...

Plumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling

Medical College, 100021, Beijing, ChinaYing-Ya Cao, Jing Yu, Ting-Ting Liu, Kai-Xia Yang, Li-Yan Yang, Feng Shi, Jia-Jie Hao, Yan Cai, Ming-Rong Wang & Yu ZhangDepartment of Intensive Care Medicine ... in:Nature Research journals • PubMed • Google Scholar Search for Ting-Ting Liu in:Nature Research journals • PubMed • Google Scholar Search for Kai-Xia Yang in:Nature Research journals • PubMed • Google

Axial Force Analysis and Roll Contour Configuration of Four-High CVC Mill

In order to analyze the influence of technical parameters on work roll axial force of four-high continuous variable crown (CVC) mill, the deformation analyzing model with top roll system and strip was established based on influence function method. Then a CVC work roll curve designing scheme was proposed and it was carried out on some cold rolling mill considering the requirement...

Effect of vegetation construction on runoff and sediment yield and runoff erosion ability on slope surface

Land consolidation measures affected the underlying surface erosion environment during the early stage of vegetation construction, and then had an impact on rainfall infiltration, erosion and sediment yield. This paper adopted the field simulated rainfall experiments to analyze the function that pockets site preparation measures affected on rainfall infiltration, runoff sediment...

Effect of vegetation construction on runoff and sediment yield and runoff erosion ability on slope surface

Land consolidation measures affected the underlying surface erosion environment during the early stage of vegetation construction, and then had an impact on rainfall infiltration, erosion and sediment yield. This paper adopted the field simulated rainfall experiments to analyze the function that pockets site preparation measures affected on rainfall infiltration, runoff sediment...