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138 papers found.
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A Generalized Demodulation and Hilbert Transform Based Signal Decomposition Method

This paper proposes a new signal decomposition method that aims to decompose a multicomponent signal into monocomponent signal. The main procedure is to extract the components with frequencies higher than a given bisecting frequency by three steps: (1) the generalized demodulation is used to project the components with lower frequencies onto negative frequency domain, (2) the...

A Learning Framework of Nonparallel Hyperplanes Classifier

Received 21 June 2014; Revised 19 September 2014; Accepted 19 September 2014 Academic Editor: Qiankun Song Copyright © 2015 Zhi-Xia Yang et al. This is an open access article distributed under the

A Maladaptive Role for EP4 Receptors in Mouse Mesangial Cells

Roles of the prostaglandin E2 E-prostanoid 4 receptor (EP4) on extracellular matrix (ECM) accumulation induced by TGF-β1 in mouse glomerular mesangial cells (GMCs) remain unknown. Previously, we have identified that TGF-β1 stimulates the expression of FN and Col I in mouse GMCs. Here we asked whether stimulation of EP4 receptors would exacerbate renal fibrosis associated with...

A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension

Genome-wide association studies (GWAS) have uncovered numerous genetic variants (SNPs) that are associated with blood pressure (BP). Genetic variants may lead to BP changes by acting on intermediate molecular phenotypes such as coded protein sequence or gene expression, which in turn affect BP variability. Therefore, characterizing genes whose expression is associated with BP may...

A systems genetics study of swine illustrates mechanisms underlying human phenotypic traits

Background The pig, which shares greater similarities with human than with mouse, is important for agriculture and for studying human diseases. However, similarities in the genetic architecture and molecular regulations underlying phenotypic variations in humans and swine have not been systematically assessed. Results We systematically surveyed ~500 F2 pigs genetically and...

ABO Blood Group and the Risk of Hepatocellular Carcinoma: A Case-Control Study in Patients with Chronic Hepatitis B

Background Studies have observed an association between the ABO blood group and risk of certain malignancies. However, no studies of the association with hepatocellular carcinoma (HCC) risk are available. We conducted this hospital-based case-control study to examine the association with HCC in patients with chronic hepatitis B (CHB). Methods From January 2004 to December 2008, a...

Acceptability and Correlates of Primary and Secondary Prevention of Cervical Cancer among Medical Students in Southwest China: Implications for Cancer Education

Objectives To understand knowledge about, and acceptability of, cervical cancer screening and HPV vaccines among medical students; and to explore potential factors that influence their acceptability in China. Methods We conducted a survey among medical students at six universities across southwest China using a 58-item questionnaire regarding knowledge and perceptions of HPV...

An Iterative Algorithm for a Hierarchical Problem

A general hierarchical problem has been considered, and an explicit algorithm has been presented for solving this hierarchical problem. Also, it is shown that the suggested algorithm converges strongly to a solution of the hierarchical problem.

An iterative Algorithm for Hemicontractive Mappings in Banach Spaces

We First introduce a three-step iterative algorithm for approximating the fixed points of the hemicontractive mappings in Banach spaces. Consequently, we prove the strong convergence of the proposed algorithm under some assumptions. Since three-step iterations include Ishikawa iterations as special cases, our result continue to hold for these problems. Our main results can be...

An iterative Algorithm for Hemicontractive Mappings in Banach Spaces

We First introduce a three-step iterative algorithm for approximating the fixed points of the hemicontractive mappings in Banach spaces. Consequently, we prove the strong convergence of the proposed algorithm under some assumptions. Since three-step iterations include Ishikawa iterations as special cases, our result continue to hold for these problems. Our main results can be...

Analysis of Startup Process and Its Optimization for a Two-Stand Reversible Cold Rolling Mill

Dynamic characteristic analysis of a two-stand reversible cold rolling mill in the startup process was carried out. The delay algorithm of the interstand thickness was proposed. A new method combined with the accelerated secant and the tangent methods was established to solve the simultaneous equations. The thickness and interstand tension transition processes with different...

Analysis of Startup Process and Its Optimization for a Two-Stand Reversible Cold Rolling Mill

Dynamic characteristic analysis of a two-stand reversible cold rolling mill in the startup process was carried out. The delay algorithm of the interstand thickness was proposed. A new method combined with the accelerated secant and the tangent methods was established to solve the simultaneous equations. The thickness and interstand tension transition processes with different...

Angiotensin II induces extracellular matrix metalloproteinase inducer expression via an AT1R dependent pathway in aortic atherosclerotic plaque in apolipoprotein E knockout mice

The pathogenesis of acute coronary syndrome is rupture of vulnerable plaque. Extracellular matrix metalloproteinase inducer (EMMPRIN) is reported to have a important role in the destabilization of atheroma. Objectives: this investigation examined the effect of angiotensin II (Ang II) on EMMPRIN expression in atherosclerotic plaques in ApoE knockout mice. Methods: ApoE knockout...

Anthraquinone G503 Induces Apoptosis in Gastric Cancer Cells through the Mitochondrial Pathway

G503 is an anthraquinone compound isolated from the secondary metabolites of a mangrove endophytic fungus from the South China Sea. The present study elucidates the anti-tumor activity and the underlying mechanism of G503. Cell viability assay performed in nine cancer cell lines and two normal cell lines demonstrated that the gastric cancer cell line SGC7901 is the most G503...

Are CD4+CD25-Foxp3+ cells in untreated new-onset lupus patients regulatory T cells?

Introduction Our previous study has reported that, in patients with untreated new-onset lupus (UNOL), there was an abnormal increase in the number of CD4+CD25-Foxp3+ T cells that correlated with disease activity and significantly decreased after treatment. However, little is known about the nature of this cell entity. The aim of this study was to explore the nature of abnormally...

Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes

L-ascorbic acid (Vitamin C) can enhance the meiotic maturation and developmental competence of porcine oocytes, but the underlying molecular mechanism remains obscure. Here we show the role of ascorbic acid in regulating epigenetic status of both nucleic acids and chromatin to promote oocyte maturation and development in pigs. Supplementation of 250 μM L-ascorbic acid 2-phosphate...

Association between maternal HIV infection and low birth weight and prematurity: a meta-analysis of cohort studies

Background To assess the association between maternal human immunodeficiency virus (HIV) infection and low birth weight (LBW)/prematurity (PTD), we conducted a meta-analysis of cohort studies of HIV infected and uninfected women. Methods Several English and Chinese databases were searched (updated to May 2015) to find the studies reporting infant outcomes associated with exposure...

Association of low skeletal muscle index with increased systematic inflammatory responses and interferon γ-induced protein 10 levels in patients with colon cancer

Association of low skeletal muscle index with increased systematic inflammatory responses and interferon gamma-induced protein 10 levels in patients with colon cancer Wen-Zhuo He,1,* Qiu-Xia Yang,2 ... Weinberg Peer reviewer comments 3 Editor who approved publication: Professor Nakshatri Wen-Zhuo He,1,* Qiu-Xia Yang,2,* Jin-Ye Xie,3,* Peng-Fei Kong,1 Wan-Ming Hu,4 Lin Yang,1 Yuan