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Tumor necrosis factor receptor-associated protein 1 regulates hypoxia-induced apoptosis through a mitochondria-dependent pathway mediated by cytochrome c oxidase subunit II

BackgroundTumor necrosis factor receptor-associated protein 1 (TRAP1) plays a protective effect in hypoxic cardiomyocytes, but the precise mechanisms are not well clarified. The study is aimed to identify the mechanism of TRAP1 on hypoxic damage in cardiomyocytes.MethodsIn this study, the effects of TRAP1 and cytochrome c oxidase subunit II (COXII) on apoptosis in hypoxia-induced...

Tumor necrosis factor receptor-associated protein 1 regulates hypoxia-induced apoptosis through a mitochondria-dependent pathway mediated by cytochrome c oxidase subunit II

Tumor necrosis factor receptor-associated protein 1 (TRAP1) plays a protective effect in hypoxic cardiomyocytes, but the precise mechanisms are not well clarified. The study is aimed to identify the mechanism of TRAP1 on hypoxic damage in cardiomyocytes. In this study, the effects of TRAP1 and cytochrome c oxidase subunit II (COXII) on apoptosis in hypoxia-induced cardiomyocytes...

MPC1 deficiency accelerates lung adenocarcinoma progression through the STAT3 pathway

Tumor Immunopathology, Ministry of Education of China, Chongqing, ChinaHongbo Zou, Qian Chen, Songtao Wang, Hong Wu, Ye Yuan, Shuang Wang, Jing Yu, Xianmei Wen, Wenjuan Fu, Xia Zhang, Guoxiang Jin & Chuan ... in:Nature Research journals • PubMed • Google Scholar Search for Haitao Lan in:Nature Research journals • PubMed • Google Scholar Search for Xia Zhang in:Nature Research journals • PubMed • Google Scholar

Intestinal metastasis from primary ROS1-positive lung adenocarcinoma cancer patients responding to crizotinib

Intestinal metastasis from primary ROS1-positive lung adenocarcinoma cancer patients responding to crizotinib Hua-fei Chen,1,* Qu-xia Zhang,2,* You-cai Zhu,1 Kai-qi Du,1 Xiao-feng Li,1 Li-xin Wu,1

Photovoltaic Performance of Pin Junction Nanocone Array Solar Cells with Enhanced Effective Optical Absorption

The photovoltaic performance of axial and radial pin junction GaAs nanocone array solar cells is investigated. Compared with the cylinder nanowire arrays, the nanocone arrays not only improve the whole optical absorption but more importantly enhance the effective absorption (absorption in the depletion region). The enhanced effective absorption is attributed to the downward shift...

Elemene treatment for NSCLC with multiple CNS metastases: a case report and literature review

Elemene treatment for NSCLC with multiple CNS metastases: a case report and literature review Yushan Han,1,* Xia Zhang,2,* Yishan Lu,3,4 Yan Dong,1 Hong Fu,1 Bin Zhang,1 Yajie Gao1 1Department of

Channel Plasmon Nanowire Lasers with V-Groove Cavities

A hybrid channel plasmon nanowire laser based on GaAs/AlGaAs core-shell semiconductor nanowire and silver V-groove is proposed. The laser structure has potential capability of integrating with plasmonic waveguides, using channel plasmon-polariton modes in V-groove plasmonic waveguides. Guiding and lasing properties are numerically calculated using finite elements method. From the...

A Review of Nontraditional Biomanipulation

The aim of this review is to identify problems, find general patterns, and extract recommendations for successful management using nontraditional biomanipulation to improve water quality. There are many obstacles that prevent traditional biomanipulation from achieving expectations: expending largely to remove planktivorous fish, reduction of external and internal phosphorus, and...

Erratum to: Study on the effect of ellipticity and misalignment on OAM modes in a ring fiber

affiliations Li-li Zhang (张丽丽)Xia Zhang (张霞)Cheng-lin Bai (白成林) Erratum First Online: 19 July 2018 The original article can be found online at  https://doi.org/10.1007/s11801-018-7251-6

A Human-Robot Interaction Based Coordination Control Method for Assistive Walking Devices and an Assessment of Its Stability

-1 Tokida, Ueda, Nagano 386-8567, Japan Correspondence should be addressed to Xia Zhang; moc.621@215xz Received 29 January 2018; Revised 7 May 2018; Accepted 5 July 2018; Published 18 July 2018 ... Academic Editor: Carlos Perez-Vidal Copyright © 2018 Xia Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution

A Human-Robot Interaction Based Coordination Control Method for Assistive Walking Devices and an Assessment of Its Stability

-1 Tokida, Ueda, Nagano 386-8567, Japan Correspondence should be addressed to Xia Zhang; moc.621@215xz Received 29 January 2018; Revised 7 May 2018; Accepted 5 July 2018; Published 18 July 2018 ... Academic Editor: Carlos Perez-Vidal Copyright © 2018 Xia Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution

The effects of genetic variation and environmental factors on rhynchophylline and isorhynchophylline in Uncaria macrophylla Wall. from different populations in China

: Xiao-Jun Ma. Investigation: Yan-Hong Guan, Hai-Tao Li, Shu-Gen Wei, Li-Xia Zhang. Methodology: Mei-Fang Song, Zhong-Lian Zhang. Project administration: Zhong-Lian Zhang, Xiao-Jun Ma. Resources: Mei

Possible pentaquark candidates: new excited \(\Omega _c\) states

Eur. Phys. J. C Zhi-Gang Wang 0 Jun-Xia Zhang 0 0 Department of Physics, North China Electric Power University , Baoding 071003 , People's Republic of China In this article, we study the

Clinical characteristics of a concurrent condition of IgG4-RD and Castleman’s disease

IgG4-related disease (IgG4-RD) and Castleman’s disease (CD) share similar clinical manifestations. When the histopathology coincides with the diagnosis of both IgG4-RD and CD, it is hard to depart the two disease entities utterly; here we call it IgG4-CD provisionally. In this study, we aim to review the clinical features of IgG4-CD. This study is based on a retrospective...

Chromosomal microarray analysis in developmental delay and intellectual disability with comorbid conditions

Developmental delay (DD) and intellectual disability (ID) are frequently associated with a broad spectrum of additional phenotypes. Chromosomal microarray analysis (CMA) has been recommended as a first-tier test for DD/ID in general, whereas the diagnostic yield differs significantly among DD/ID patients with different comorbid conditions. To investigate the genotype-phenotype...

Optimization of GaAs Nanowire Pin Junction Array Solar Cells by Using AlGaAs/GaAs Heterojunctions

We optimized the performance of GaAs nanowire pin junction array solar cells by introducing AlGaAs/GaAs heterejunctions. AlGaAs is used for the p type top segment for axial junctions and the p type outer shell for radial junctions. The AlGaAs not only serves as passivation layers for GaAs nanowires but also confines the optical generation in the active regions, reducing the...

Popularity and Novelty Dynamics in Evolving Networks

Network science plays a big role in the representation of real-world phenomena such as user-item bipartite networks presented in e-commerce or social media platforms. It provides researchers with tools and techniques to solve complex real-world problems. Identifying and predicting future popularity and importance of items in e-commerce or social media platform is a challenging...

Capillary morphogenesis gene 2 maintains gastric cancer stem-like cell phenotype by activating a Wnt/β-catenin pathway

A growing body of evidence shows that the development and progression of gastric cancer (GC) is mainly associated to the presence of gastric cancer stem-like cells (GCSLCs). However, it is unclear how GCSLC population is maintained. This study aimed to explore the role of capillary morphogenesis gene 2 (CMG2) in GCSLC maintenance and the relevance to GC progression. We found that...

Photovoltaic Performance of a Nanowire/Quantum Dot Hybrid Nanostructure Array Solar Cell

An innovative solar cell based on a nanowire/quantum dot hybrid nanostructure array is designed and analyzed. By growing multilayer InAs quantum dots on the sidewalls of GaAs nanowires, not only the absorption spectrum of GaAs nanowires is extended by quantum dots but also the light absorption of quantum dots is dramatically enhanced due to the light-trapping effect of the...