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CP and CP-PGN protect mice against MRSA infection by inducing M1 macrophages

Xian-Feng Zhang, Jin-Fang Shi & Qing-Zhen Han AuthorsSearch for Yang Zhang in:Nature Research journals • PubMed • Google Scholar Search for Xiang-Xiang Li in:Nature Research journals • PubMed • Google ... • PubMed • Google Scholar Search for Xue-Feng Qian in:Nature Research journals • PubMed • Google Scholar Search for Xian-Feng Zhang in:Nature Research journals • PubMed • Google Scholar Search for Jin

Generation of transgenic marmosets expressing genetically encoded calcium indicators

Chronic monitoring of neuronal activity in the living brain with optical imaging techniques became feasible owing to the continued development of genetically encoded calcium indicators (GECIs). Here we report for the first time the successful generation of transgenic marmosets (Callithrix jacchus), an important nonhuman primate model in neurophysiological research, which were...

Primary carcinoid tumor of medulla spinalis: case report and review of the literature

Background Carcinoid tumors are slow growing neuroendocrine tumors which can originate from various sites within the body. A carcinoid tumor originating in the medulla spinalis has not previously been reported in the literature. Case report We report a case of a 33-year-old man, presenting with a five-month history of bilateral lower extremity pain, as well as paresthesia, and...

Primary carcinoid tumor of medulla spinalis: case report and review of the literature

Carcinoid tumors are slow growing neuroendocrine tumors which can originate from various sites within the body. A carcinoid tumor originating in the medulla spinalis has not previously been reported in the literature. We report a case of a 33-year-old man, presenting with a five-month history of bilateral lower extremity pain, as well as paresthesia, and mild weakness in one...

Nore1 inhibits tumor cell growth independent of Ras or the MST1/2 kinases

Nore1, a noncatalytic protein identified by its ability to bind selectively to active Ras, is most closely related in amino-acid sequence to the tumor suppressor RASSF1. Both are expressed predominantly as a longer (Nore1A/RASSF1A) and/or shorter (Nore1B/RASSF1C) polypeptide; all four polypeptides contain a Ras-association domain and bind, through their conserved carboxytermini...

The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1

, Andrei Khokhlatchev, Maria Nedwidek, Xian-feng Zhang & Joseph AvruchDepartment of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, MA 02114, USASara Ortiz-Vega & Andrei ... Maria Nedwidek in:Nature Research journals • PubMed • Google ScholarSearch for Xian-feng Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Reinhard Dammann in:Nature Research journals