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Transforming ground mica into high-performance biomimetic polymeric mica film

Biomimetic assembly of high-quality nanosheets into nacre-like structures can produce macroscopic films with favorable mechanical and optical performances due to the intrinsic properties and high level of ordering of the nanoscale building blocks. Natural ground mica is abundant and exhibits great application potential. However, large size and low aspect ratio greatly limit its...

Active sites of copper-complex catalytic materials for electrochemical carbon dioxide reduction

Restructuring-induced catalytic activity is an intriguing phenomenon of fundamental importance to rational design of high-performance catalyst materials. We study three copper-complex materials for electrocatalytic carbon dioxide reduction. Among them, the copper(II) phthalocyanine exhibits by far the highest activity for yielding methane with a Faradaic efficiency of 66% and a...

The structure of Zika virus NS5 reveals a conserved domain conformation

No DE-AC02-05CH11231. Author information Author notesBoxiao Wang & Xiao-Feng Tan These authors contributed equally to this work. AffiliationsDepartment of Biochemistry, University of California ... , Riverside, Riverside, California 92521, USABoxiao Wang, Xiao-Feng Tan, Zhi-Min Zhang, Asher Lin & Jikui SongDepartment of Plant Pathology and Microbiology, University of California, Riverside, Riverside

Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone

The global spread of Zika virus (ZIKV) and its unexpected association with congenital defects necessitates the rapid development of a safe and effective vaccine. Here we report the development and characterization of a recombinant chimeric ZIKV vaccine candidate (termed ChinZIKV) that expresses the prM-E proteins of ZIKV using the licensed Japanese encephalitis live-attenuated...

Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells

& Peking Union Medical College, Beijing 100005, ChinaF. Xiao-Feng QinSuzhou Institute of Systems Medicine, Suzhou 215123, ChinaF. Xiao-Feng Qin AuthorsSearch for Yuying Liu in:Nature Research journals ... ScholarSearch for Zhuo-Wei Hu in:Nature Research journals • PubMed • Google ScholarSearch for Xuetao Cao in:Nature Research journals • PubMed • Google ScholarSearch for F. Xiao-Feng Qin in:Nature Research

CaMKII-mediated Beclin 1 phosphorylation regulates autophagy that promotes degradation of Id and neuroblastoma cell differentiation

Autophagy is a degradative pathway that delivers cellular components to the lysosome for degradation. The role of autophagy in cell differentiation is poorly understood. Here we show that CaMKII can directly phosphorylate Beclin 1 at Ser90 to promote K63-linked ubiquitination of Beclin 1 and activation of autophagy. Meanwhile, CaMKII can also promote K63-linked ubiquitination of...

The tapetal AHL family protein TEK determines nexine formation in the pollen wall

Professor Sheila McCormick and Professor Yunde Zhao for critical reading and revising of the manuscript. Author information Author notesYue Lou, Xiao-Feng Xu & Jun Zhu These authors contributed equally to ... this work AffiliationsCollege of Life and Environment Sciences, Development Center of Plant Germplasm Resources, Shanghai Normal University, Shanghai 200234, ChinaYue Lou, Xiao-Feng Xu, Jun Zhu, Jing-Nan

Electrically tuned magnetic order and magnetoresistance in a topological insulator

The interplay between topological protection and broken time reversal symmetry in topological insulators may lead to highly unconventional magnetoresistance behaviour that can find unique applications in magnetic sensing and data storage. However, the magnetoresistance of topological insulators with spontaneously broken time reversal symmetry is still poorly understood. In this...

Pore surface engineering in covalent organic frameworks

Molecular Science, National Institutes of Natural Sciences, 5-1 Higashiyama, Okazaki 444-8787, Japan.Atsushi Nagai, Zhaoqi Guo, Xiao Feng, Shangbin Jin, Xiong Chen, Xuesong Ding & Donglin JiangPrecursory ... • PubMed • Google ScholarSearch for Zhaoqi Guo in:Nature Research journals • PubMed • Google ScholarSearch for Xiao Feng in:Nature Research journals • PubMed • Google ScholarSearch for Shangbin Jin in:Nature

The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes

Sachpatzidis, Daniel Schlingman, Xiao-Feng Zheng, Lynne Regan, Patrick Sung & Yong XiongDivision of Experimental Hematology and Cancer Biology, Cincinnati Children’s Research Foundation and University of ... for Xiao-Feng Zheng in:Nature Research journals • PubMed • Google ScholarSearch for Andrew Mack in:Nature Research journals • PubMed • Google ScholarSearch for Miaw-Sheue Tsai in:Nature Research

Skp2–MacroH2A1–CDK8 axis orchestrates G2/M transition and tumorigenesis

, ChinaDazhi Xu, Xiao-Feng Zhu & Yi-Xin ZengDepartment of Molecular and Cellular Oncology, M.D. Anderson Cancer Center, The University of Texas, 1515 Holcombe Boulevard, Houston, Texas 77030, USADazhi Xu, Xian ... in:Nature Research journals • PubMed • Google ScholarSearch for Lu-Ping Chow in:Nature Research journals • PubMed • Google ScholarSearch for Xiao-Feng Zhu in:Nature Research journals • PubMed • Google