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AKI in the very elderly patients without preexisting chronic kidney disease: a comparison of 48-hour window and 7-day window for diagnosing AKI using the KDIGO criteria

AKI in the very elderly patients without preexisting chronic kidney disease: a comparison of 48-hour window and 7-day window for diagnosing AKI using the KDIGO criteria Qinglin Li,1 Meng Zhao,2 Xiaodan Wang1 1Department of Health Care, Nanlou Division, Chinese PLA General Hospital, National Clinical Research Center for Geriatric Diseases, Beijing, China; 2Department of Clinical...

Risk assessment of deoxynivalenol in high-risk area of China by human biomonitoring using an improved high throughput UPLC-MS/MS method

A risk assessment of deoxynivalenol (DON) was recently conducted for the residents in Henan province, China, where wheat as the staple food are highly consumed. A high-throughput sensitive UPLC-MS/MS method following 96-well μElution solid-phase extraction (SPE) were developed and validated for the determination of DON biomarkers in human urine. Isotope labelled internal standard...

Outcomes of renal function in elderly patients with acute kidney injury

Outcomes of renal function in elderly patients with acute kidney injury Qinglin Li,1 Meng Zhao,2 Jing Du,1 Xiaodan Wang1,3 1Department of Geriatric Nephrology, 2Department of Clinical Data Repository, 3Department of Health Care, Chinese PLA General Hospital, Beijing, People’s Republic of China Objectives: The aim of this study was to explore the prognostic impact of clinical...

Earlier nephrology consultation may not be associated with improved short-term survival of acute kidney injury in very elderly men

Xiaodan Wang 1 0 Department of Clinical Data repository , Chinese People's liberation Army general hospital, Beijing , China 1 Department of geriatric n ephrology PowerdbyTCPDF(ww.tcpdf.org) Objectives: A

Genetic variability and functional implication of the long control region in HPV-16 variants in Southwest China

, Qiangming Sun. Investigation: Juemin Xi, Junying Chen. Methodology: Junying Chen, Xiaodan Wang, Lijuan Qiu. Project administration: Qiangming Sun. Resources: Miaoling Xu, Hongying Yang. Software: Jia Luo

Folic acid-functionalized drug delivery platform of resveratrol based on Pluronic 127/D-α-tocopheryl polyethylene glycol 1000 succinate mixed micelles

Zhuang, Te Han, Yanping Bi, Jianzhu Wang, Xiaodan Wang College of Pharmacy, Taishan Medical University, Taian, People’s Republic of China *These authors contributed equally to this work Abstract: A folic

Impact of atmospheric and oceanic conditions on the frequency and genesis location of tropical cyclones over the western North Pacific in 2004 and 2010

This study examines the impact of atmospheric and oceanic conditions during May–August of 2004 and 2010 on the frequency and genesis location of tropical cyclones over the western North Pacific. Using the WRF model, four numerical experiments were carried out based on different atmospheric conditions and SST forcing. The numerical experiments indicated that changes in atmospheric...

Infinitely many solutions for a fourth-order differential equation on a nonlinear elastic foundation

In this paper, existence results of infinitely many solutions for a fourth-order differential equation with nonlinear boundary conditions are established. The proof is based on variational methods. Some recent results are improved and extended.

Stoichiometry of Root and Leaf Nitrogen and Phosphorus in a Dry Alpine Steppe on the Northern Tibetan Plateau

Leaf nitrogen (N) and phosphorus (P) have been used widely in the ecological stoichiometry to understand nutrient limitation in plant. However,few studies have focused on the relationship between root nutrients and environmental factors. The main objective of this study was to clarify the pattern of root and leaf N and P concentrations and the relationships between plant nitrogen...

Prevalence of primary headache disorders in a population aged 60 years and older in a rural area of Northern China

Background Primary headache disorders are among the most common neurological complaints worldwide, and are significant causes of disability. Data are limited on the prevalence of primary headaches among individuals aged 60 years and older in China. The purpose of our study was to investigate the prevalence and characteristics of primary headaches among people aged 60 years and...

Prevalence of primary headache disorders in a population aged 60 years and older in a rural area of Northern China

Primary headache disorders are among the most common neurological complaints worldwide, and are significant causes of disability. Data are limited on the prevalence of primary headaches among individuals aged 60 years and older in China. The purpose of our study was to investigate the prevalence and characteristics of primary headaches among people aged 60 years and older in a...

Effects of Grazing Regimes on Plant Traits and Soil Nutrients in an Alpine Steppe, Northern Tibetan Plateau

Understanding the impact of grazing intensity on grassland production and soil fertility is of fundamental importance for grassland conservation and management. We thus compared three types of alpine steppe management by studying vegetation traits and soil properties in response to three levels of grazing pressure: permanent grazing (M1), seasonal grazing (M2), and grazing...

Transcriptome and Molecular Pathway Analysis of the Hepatopancreas in the Pacific White Shrimp Litopenaeus vannamei under Chronic Low-Salinity Stress

The Pacific white shrimp Litopenaeus vannamei is a euryhaline penaeid species that shows ontogenetic adaptations to salinity, with its larvae inhabiting oceanic environments and postlarvae and juveniles inhabiting estuaries and lagoons. Ontogenetic adaptations to salinity manifest in L. vannamei through strong hyper-osmoregulatory and hypo-osmoregulatory patterns and an ability...

Molecular Characterization and Viral Origin of the 2015 Dengue Outbreak in Xishuangbanna, Yunnan, China

Luo Zhiqiang Ma Xiaodan Wang Yue Pan Junying Chen Juemin Xi JiajiaYang Lijuan Qiu Chunhai Bai Liming Jiang Xiyun Shan Qiangming Sun OPEN A total of 1067 serum samples were collected from febrile

Transcriptome Profiling and Molecular Pathway Analysis of Genes in Association with Salinity Adaptation in Nile Tilapia Oreochromis niloticus

Nile tilapia Oreochromis niloticus is a freshwater fish but can tolerate a wide range of salinities. The mechanism of salinity adaptation at the molecular level was studied using RNA-Seq to explore the molecular pathways in fish exposed to 0, 8, or 16 (practical salinity unit, psu). Based on the change of gene expressions, the differential genes unions from freshwater to saline...

Responses of Soil CO2 Fluxes to Short-Term Experimental Warming in Alpine Steppe Ecosystem, Northern Tibet

Soil carbon dioxide (CO2) emission is one of the largest fluxes in the global carbon cycle. Therefore small changes in the size of this flux can have a large effect on atmospheric CO2 concentrations and potentially constitute a powerful positive feedback to the climate system. Soil CO2 fluxes in the alpine steppe ecosystem of Northern Tibet and their responses to short-term...

Biomass Partitioning and Its Relationship with the Environmental Factors at the Alpine Steppe in Northern Tibet

Alpine steppe is considered to be the largest grassland type on the Tibetan Plateau. This grassland contributes to the global carbon cycle and is sensitive to climate changes. The allocation of biomass in an ecosystem affects plant growth and the overall functioning of the ecosystem. However, the mechanism by which plant biomass is allocated on the alpine steppe remains unclear...

Epigenetic synergy between decitabine and platinum derivatives

Background Aberrant epigenetic silencing of tumor suppressor genes has been recognized as a driving force in cancer. Epigenetic drugs such as the DNA methylation inhibitor decitabine reactivate genes and are effective in myeloid leukemia, but resistance often develops and efficacy in solid tumors is limited. To improve their clinical efficacy, we searched among approved anti...

Role of cullin-elonginB-elonginC E3 complex in bovine immunodeficiency virus and maedi-visna virus Vif-mediated degradation of host A3Z2-Z3 proteins

Background All lentiviruses except equine infectious anemia virus (EIVA) antagonize antiviral family APOBEC3 (A3) proteins of the host through viral Vif proteins. The mechanism by which Vif of human, simian or feline immunodeficiency viruses (HIV/SIV/FIV) suppresses the corresponding host A3s has been studied extensively. Results Here, we determined that bovine immunodeficiency...

Improved long-term expression from helper virus-free HSV-1 vectors packaged using combinations of mutated HSV-1 proteins that include the UL13 protein kinase and specific components of the VP16 transcriptional complex

Meng Liu 0 Xiaodan Wang 0 Alfred I Geller 0 0 Address: Department of Neurology, West Roxbury VA Hospital/Harvard Medical School , W. Roxbury, MA 02132 , USA Background: Herpes Simplex Virus (HSV