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Design of dual-band cold mirrors

Dual-band cold mirrors are designed based on third-order of 121.6 nm multilayers, and they are only composed of LaF3 and MgF2. The designed mirrors have a high reflectance at 121.6 nm and 280 nm, and a low reflectance in visible waveband; they also have a narrow bandwidth of 4 nm at 121.6 nm, and low sidelobe ripples of two stopbands. A broadband antireflection coating and an...

Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments

Road, Xi’an, 710054, Shanxi, ChinaBiao Wang, Lingbo Kong, Ziqi Zhu, Wenjie Gao, Hua Guo, Xiaodong Wang, Hui Li, Qinpeng Zhao, Haiping Zhang & Dingjun Hao AuthorsSearch for Biao Wang in:Nature Research ... Gao in:Nature Research journals • PubMed • Google Scholar Search for Hua Guo in:Nature Research journals • PubMed • Google Scholar Search for Xiaodong Wang in:Nature Research journals • PubMed

A Pilot Study on Tocilizumab for Treating Refractory Adult-Onset Still’s Disease

To investigate the efficacy and safety of Tocilizumab (TCZ) in patients with refractory adult-onset Still’s disease (AOSD). We enrolled 8 female patients from October 2013 to July 2014. All patients fulfilled Japan’s Yamaguch AOSD classification and recognized as refractory AOSD. All Patients received TCZ treatment 4–8 mg/kg every 4 weeks. Evaluation of efficacy was conducted...

Synthesis of renewable high-density fuel with isophorone

1,1,3-Trimethyl-5-(2,4,4-trimethylcyclohexyl)cyclohexane, a renewable high density fuel, was first produced in a high overall carbon yield (~70%) with isophorone which can be derived from hemicellulose. The synthetic route used this work contains three steps. In the first step, 3,3,5-trimethylcyclohexanone was synthesized by the selective hydrogenation of isophorone. Among the...

Synthesis of jet fuel range branched cycloalkanes with mesityl oxide and 2-methylfuran from lignocellulose

Jet fuel range branched cycloalkanes with high density (0.82 g mL−1) and low freezing point (217–219 K) was first prepared by the solvent-free intramolecular aldol condensation of the trione from the hydrolysis of the alkylation product of mesityl oxide and 2-methylfuran (or the one-pot reaction of mesityl oxide, 2-methylfuran and water), followed by hydrodeoxygenation (HDO).

Immunomodulatory and Antitumor Effects of a Novel TLR7 Agonist Combined with Lapatinib

for Synthetic Biology of Medicine, Shenzhen University, Shenzhen 518060, People’s Republic of ChinaNingning Gao, Jingjing Zhong, Xiaodong Wang, Zhenchao Jin, Wang Li, Yu Liu, Yuwen Diao & Guangyi ... JinCancer Research Center, Shenzhen University, Shenzhen 518060, People’s Republic of ChinaNingning Gao, Jingjing Zhong, Xiaodong Wang, Zhenchao Jin, Wang Li, Yu Liu, Yuwen Diao, Wenqi Jiang & Guangyi

Pirfenidone in patients with rapidly progressive interstitial lung disease associated with clinically amyopathic dermatomyositis

Chen Xiaodong Wang ShuangYe OPEN To evaluate the efficacy of pirfenidone in patients with rapidly progressive interstitial lung disease (RPILD) related to clinically amyopathic dermatomyositis (CADM

Evolutionary features of thyroid cancer in patients with thyroidectomies from 2008 to 2013 in China

Erik K. Alexander in:Nature Research journals • PubMed • Google ScholarSearch for Tao Yang in:Nature Research journals • PubMed • Google ScholarSearch for Xiaodong Wang in:Nature Research journals ... Correspondence to Tao Yang or Xiaodong Wang. Supplementary information Word documents1.Supplementary Information Rights and permissions This work is licensed under a Creative Commons Attribution 4.0

Synthesis of high density aviation fuel with cyclopentanol derived from lignocellulose

For the first time, renewable high density aviation fuels were synthesized at high overall yield (95.6%) by the Guerbet reaction of cyclopentanol which can be derived from lignocellulose, followed by the hydrodeoxygenation (HDO). The solvent-free Guerbet reaction of cyclopentanol was carried out under the co-catalysis of solid bases and Raney metals. Among the investigated...

Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays

Isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) are key metabolic enzymes that are mutated in a variety of cancers to confer a gain-of-function activity resulting in the accumulation of an oncometabolite, D-2-hydroxyglutarate (2-HG). Accumulation of 2-HG can result in epigenetic dysregulation and a block in cellular differentiation, suggesting these mutations play a role in...

Interfacial Free Energy Controlling Glass-Forming Ability of Cu-Zr Alloys

Glass is a freezing phase of a deeply supercooled liquid. Despite its simple definition, the origin of glass forming ability (GFA) is still ambiguous, even for binary Cu-Zr alloys. Here, we directly study the stability of the supercooled Cu-Zr liquids where we find that Cu64Zr36 at a supercooled temperature shows deeper undercoolability and longer persistence than other...