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7 papers found.
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Abnormal primary and permanent dentitions with ectodermal symptoms predict WNT10A deficiency

Background The WNT10A protein is critical for the development of ectodermal appendages. Variants in the WNT10A gene may be associated with a spectrum of ectodermal abnormalities including extensive tooth agenesis. Methods In seven patients with severe tooth agenesis we identified anomalies in primary dentition and additional ectodermal symptoms, and assessed WNT10A mutations by...

Studies on cellulase-ultrasonic assisted extraction technology for flavonoids from Illicium verum residues

Background Illicium verum is widely cultivated in southern China especially in Guangxi province. Its fruits has been traditionally used in Chinese medicine. In recent years, it has been the industrial source of shikimic acid. Usually the residues after extracting shikimic acid are treated as waste. Thus, the aim of this study was to optimize the extraction conditions of cellulase...

Assessing Methotrexate Adherence in Rheumatoid Arthritis: A Cross-Sectional Survey

employee of RTI Health Solutions. Xiaolei Zhou is an employee of RTI Health Solutions. Maria Reynolds is an employee of RTI Health Solutions. RTI Health Solutions was contracted by Genentech, Inc., to design

Dual actions of albumin packaging and tumor targeting enhance the antitumor efficacy and reduce the cardiotoxicity of doxorubicin in vivo

Dual actions of albumin packaging and tumor targeting enhance the antitumor efficacy and reduce the cardiotoxicity of doxorubicin in vivo Ke Zheng,1 Rui Li,2 Xiaolei Zhou,2 Ping Hu,2 Yaxin Zhang,2 ... Zhou 1 Yaxin Zhang 1 0 Fujian Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine , Fuzhou , People's Republic of China 1 State Key Laboratory of Structural Chemistry

A Population-Based Study of Peyronie's Disease: Prevalence and Treatment Patterns in the United States

Purpose. To estimate the US prevalence of Peyronie's disease (PD) from patient-reported data and to identify diagnosis and treatment patterns. Methods. 11,420 US males ≥18 years old completed a brief web-based survey regarding the presence of PD, past treatments, and penile symptoms (Phase 1). Phase 1 respondents with PD diagnosis, history of treatment, or PD-related symptoms...

Prevalence, incidence, and treatments of Dupuytren’s disease in the United States: results from a population-based study

Background This large population-based study was conducted to estimate the prevalence of Dupuytren’s disease in US adults and describe associated treatment patterns. Methods A total of 23,103 individuals from an Internet-based research panel representative of the US population completed a brief online survey designed to identify individuals with symptoms, diagnoses, and/or...

FGFR2, FGF8, FGF10 and BMP7 as candidate genes for hypospadias

Hypospadias is a common malformation, which results from failure of urethral tube closure, and whose molecular mechanisms are still largely unknown. The normal genital development is orchestrated by the urethral plate epithelium (UPE), at the genital tubercle (GT), which has polarizing activity, controlling a network of epithelial–mesenchymal interactions, which, when disturbed...