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A transcriptome analysis of mitten crab testes (Eriocheir sinensis)

The identification of expressed genes involved in sexual precocity of the mitten crab (Eriocheir sinensis) is critical for a better understanding of its reproductive development. To this end, we constructed a cDNA library from the rapid developmental stage of testis of E. sinensis and sequenced 3,388 randomly picked clones. After processing, 2,990 high-quality expressed sequence...

A qPCR method to quantify bioavailable phosphorus using indigenous aquatic species

BackgroundBioavailable phosphorus (BAP) represents the sum of phosphorus that is readily available for algae growth and is useful to indicate the severity of eutrophication in aquatic environments.ResultsHere, a quantitative real-time PCR (qPCR)-based bioassay was developed to quantify BAP using the indigenous cyanobacterium species Anabaena sp. of Lake Tai, a large and shallow...

Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits

prevents cardiac diastolic dysfunction by inhibiting ventricular remodeling, explicable by improved mitochondrial function and increased mitochondrial biogenesis. Notes Xiaowei Zhang and Zhiwei Zhang are

Value of plasma SN-38 levels and DPD activity in irinotecan-based individualized chemotherapy for advanced colorectal cancer with heterozygous type UGT1A1*6 or UGT1A1*28

,3,* Rongyuan Zhuang,4 Xiaowei Zhang,5 Hongmin Lu,6 Hui Wang,7 Shuowen Wang,8 Qi Li,1 Chungang Wang,9 Xun Cai1 1Department of Oncology, Shanghai General Hospital, Shanghai Jiaotong University School of ... methods and experiments, carried out the laboratory experiments, analyzed the data, interpreted the results, and wrote the manuscript. Rongyuan Zhuang, Haifeng Ying, Xiaowei Zhang, Hongmin Lu, Hui Wang, Qi

Effect-based methods are key. The European Collaborative Project SOLUTIONS recommends integrating effect-based methods for diagnosis and monitoring of water quality

The present monitoring and assessment of the chemical status of water bodies fail to characterize the likelihood that complex mixtures of chemicals affect water quality. The European Collaborative Project SOLUTIONS suggests that this likelihood can be estimated with effect-based methods (EBMs) complemented by chemical screening and/or impact modeling. These methods should be used...

Elevated CO2 accelerates polycyclic aromatic hydrocarbon accumulation in a paddy soil grown with rice

Contributions Conceptualization: Xiaowei Zhang, Rong Ji, Hongyan Guo. Data curation: Fuxun Ai, Yuwei Xie. Formal analysis: Fuxun Ai, Nico Eisenhauer, Yuwei Xie. Funding acquisition: Nico Eisenhauer, Jianguo Zhu ... , Hongyan Guo. Investigation: Fuxun Ai, Yuwei Xie, Wenchao Du, Ying Yin. Methodology: Jianguo Zhu, Ying Yin, Hongyan Guo. Project administration: Xiaowei Zhang, Rong Ji, Hongyan Guo. Resources: Jianguo Zhu

Dual-electrochromic bipolar electrode-based universal platform for the construction of various visual advanced logic devices

A universal logic platform based on dual-electrochromic bipolar electrodes (BPEs) for the operation of various visual advanced logic devices was designed and constructed for the first time. Two BPEs separated by three reaction channels filled with different reaction solutions constituted the closed BPE system and were used as the initial state. Under different input combinations...

Synthetic regulatory RNAs selectively suppress the progression of bladder cancer

The traditional treatment for cancer is lack of specificity and efficacy. Modular synthetic regulatory RNAs, such as inhibitive RNA (iRNA) and active RNA (aRNA), may overcome these limitations. Here, we synthesize a new iRNA to bind the upstream activating sequence (UAS) of a minimal promoter that drives expression of artificial miRNAs (amiRNAs) targeting MYC, which represses the...


China Xiaowei Zhang Central Laboratory of the First Hospital of Lanzhou University, People’s Republic of China Huizi Ren Tumor Hospital of Institute of Medical Science of Gansu Province, People’s Republic

Indigenous species barcode database improves the identification of zooplankton

supported by the Collaborative Innovation Center for Regional Environmental Quality. 12 / 15 Author Contributions Conceptualization: Xiaowei Zhang, G. Allen Burton, Jr. Data curation: Jianghua Yang, Yuwei ... Xie. Formal analysis: Wanwan Zhang. Funding acquisition: Xiaowei Zhang. Investigation: Jingying Sun, Yuwei Xie. Methodology: Wanwan Zhang, Jingying Sun. Project administration: Jianghua Yang

Li-ion Battery Separators, Mechanical Integrity and Failure Mechanisms Leading to Soft and Hard Internal Shorts

Separator integrity is an important factor in preventing internal short circuit in lithium-ion batteries. Local penetration tests (nail or conical punch) often produce presumably sporadic results, where in exactly similar cell and test set-ups one cell goes to thermal runaway while the other shows minimal reactions. We conducted an experimental study of the separators under...

Regeneration of hyaline-like cartilage in situ with SOX9 stimulation of bone marrow-derived mesenchymal stem cells

Microfracture, a common procedure for treatment of cartilage injury, induces fibrocartilage repair by recruiting bone marrow derived mesenchymal stem cells (MSC) to the site of cartilage injury. However, fibrocartilage is inferior biomechanically to hyaline cartilage. SRY-type high-mobility group box-9 (SOX9) is a master regulator of chondrogenesis by promoting proliferation and...

Zooplankton Community Profiling in a Eutrophic Freshwater Ecosystem-Lake Tai Basin by DNA Metabarcoding

Communities of zooplankton, a critical portion of aquatic ecosystems, can be adversely affected by contamination resulting from human activities. Understanding the influence of environmental change on zooplankton communities under field-conditions is hindered by traditional labor-intensive approaches that are prone to taxonomic and enumeration mistakes. Here, metabarcoding of...

Upregulation of Tumor Necrosis Factor-α-Induced Protein 8-Like 2 mRNA Is Negatively Correlated with Serum Concentrations of Tumor Necrosis Factor-α and Interleukin 6 in Type 2 Diabetes Mellitus

Yongliang Liu,1 Xinmei Wang,2 Yan Zhao,3 Peiqing Zhao,1 Lianqing Wang,1 Qiaoli Zhai,1 Xiaowei Zhang,1 Wenxiu Tian,1 Xinxin Xiang,1 and Tao Li1 1Central of Translation Medicine, Zibo Central Hospital

Bmi-1 regulates stem cell-like properties of gastric cancer cells via modulating miRNAs

Background B cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) plays an important role in regulating stemness in some kinds of cancer. However, the mechanisms remain unclear. This study was to investigate whether and how Bmi-1 regulates stemness of gastric cancer. Methods We firstly explored the role of Bmi-1 in regulating stem cell-like features in gastric...

Estimate Hand Poses Efficiently from Single Depth Images

This paper aims to tackle the practically very challenging problem of efficient and accurate hand pose estimation from single depth images. A dedicated two-step regression forest pipeline is proposed: given an input hand depth image, step one involves mainly estimation of 3D location and in-plane rotation of the hand using a pixel-wise regression forest. This is utilized in step...

Hyperuricemia and the risk for coronary heart disease morbidity and mortality a systematic review and dose-response meta-analysis

, Nanchang 330006, People’s Republic of ChinaMin Li, Kun Li, Xiaowei Zhang, Wenshang Hou & Zhenyu TangDepartment of Anaesthesiology, The Second Affiliated Hospital to Nanchang University, Nanchang 330006 ... Li in:Nature Research journals • PubMed • Google ScholarSearch for Xiaowei Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Wenshang Hou in:Nature Research journals • PubMed

DELLA proteins are common components of symbiotic rhizobial and mycorrhizal signalling pathways

for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, ChinaYue Jin, Huan Liu, Dexian Luo, Wentao Dong, Chao Wang, Xiaowei Zhang, Huiling Dai, Jun Yang & Ertao WangUniversity of Chinese ... journals • PubMed • Google ScholarSearch for Xiaowei Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Huiling Dai in:Nature Research journals • PubMed • Google ScholarSearch for Jun Yang

Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway

Background Tick-borne encephalitis virus (TBEV) is one of the most important flaviviruses that targets the central nervous system (CNS) and causes encephalitides in humans. Although neuroinflammatory mechanisms may contribute to brain tissue destruction, the induction pathways and potential roles of specific chemokines in TBEV-mediated neurological disease are poorly understood...

Effect of Kuijie Granule on the Expression of TGF-β/Smads Signaling Pathway in Patients with Ulcerative Colitis

Zhang,7 Jiangong Hu,7 and Weidong Li8 1Traditional Chinese Medicine Department, Affiliated Hospital of Taishan Medical University, Shandong 271000, China 2Gastroenterology Department, Chengdu Second