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Use of reproducible research practices in public health: A survey of public health analysts

, Douglas A. Luke. Data curation: Bobbi J. Carothers, Xiaoyan Wang. Formal analysis: Jenine K. Harris, Todd B. Combs. Funding acquisition: Jenine K. Harris. Methodology: Jenine K. Harris, Kimberly J ... . Johnson, Bobbi J. Carothers, Todd B. Combs, Xiaoyan Wang. Project administration: Jenine K. Harris. 10 / 12 Supervision: Jenine K. Harris. Visualization: Jenine K. Harris, Todd B. Combs. Writing

Co-stimulation of LPAR1 and S1PR1/3 increases the transplantation efficacy of human mesenchymal stem cells in drug-induced and alcoholic liver diseases

BackgroundOne of the major obstacles facing stem cell therapy is the limited number of functional stem cells available after transplantation due to the harsh microenvironment surrounding the damaged tissue. The aim of this study was to delineate the mechanistic involvement of lysophosphatidic acid receptors (LPARs) and sphingosine-1-phosphate receptors (S1PRs) in the regulation...

Potential Roles of Dental Pulp Stem Cells in Neural Regeneration and Repair

This review summarizes current advances in dental pulp stem cells (DPSCs) and their potential applications in the nervous diseases. Injured adult mammalian nervous system has a limited regenerative capacity due to an insufficient pool of precursor cells in both central and peripheral nervous systems. Nerve growth is also constrained by inhibitory factors (associated with central...

A Study on the Convergence of Family Particle Swarm Optimization

The sociological concept of family has been introduced in the particle swarm optimization (PSO) and the family PSO (FPSO) has been proposed, in which the particle swarm consisted of different families, each family consisted of different members, and there were different constraint relationships between family members. To further study the sensitivity of FPSO to the control...

The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow

ShaoDepartment of Pharmaceutical Sciences and Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USAJianhui Chang, Wei Feng, Xiaoyan Wang & Daohong ... • Google Scholar Search for Xiaoyan Wang in:Nature Research journals • PubMed • Google Scholar Search for Elizabeth A. Williamson in:Nature Research journals • PubMed • Google Scholar Search for Ying Li

The global Minmax k-means algorithm

The global k-means algorithm is an incremental approach to clustering that dynamically adds one cluster center at a time through a deterministic global search procedure from suitable initial positions, and employs k-means to minimize the sum of the intra-cluster variances. However the global k-means algorithm sometimes results singleton clusters and the initial positions...

Effects of research complexity and competition on the incidence and growth of coauthorship in biomedicine

Background Investigations into the factors behind coauthorship growth in biomedical research have mostly focused on specific disciplines or journals, and have rarely controlled for factors in combination or considered changes in their effects over time. Observers often attribute the growth to the increasing complexity or competition (or both) of research practices, but few...

Metabolomics in Cancer Biomarker Research

Purpose of Review As a research tool for quantitative measurement of small molecule metabolites, metabolomics has been devoted to search for biomarkers that can be used for diagnosis and prognosis of malignant tumors. The purpose of this review is to summarize recent literatures on metabolomic-based cancer biomarker research and to discuss the current issues and challenges in the...

The tumor suppressor phosphatase PP2A-B56α regulates stemness and promotes the initiation of malignancies in a novel murine model

curation: Mahnaz Janghorban, Derek Zachman, Colin J. Daniel, Anupriya Agarwal. Formal analysis: Mahnaz Janghorban, Ellen M. Langer, Xiaoyan Wang, Derek Zachman, Jody Hooper, Rosalie C. Sears. Funding ... acquisition: Rosalie C. Sears. Investigation: Mahnaz Janghorban, Rosalie C. Sears. Methodology: Mahnaz Janghorban, Xiaoyan Wang, Derek Zachman. Project administration: Mahnaz Janghorban. Resources: Mahnaz

The decreased expression of TIPE2 protein in the decidua of patients with missed abortion and possible significance

Missed abortion is a common occurrence for otherwise healthy women. Immunological factor is one of the most important reasons. Tumor necrosis factor-α-induced protein-8 like-2 (TIPE2) is a novel negative immune regulator related to several human diseases. However, the expression level and clinical significance of TIPE2 in missed abortion remain unclear. The expression of TIPE2...

PEAK1, acting as a tumor promoter in colorectal cancer, is regulated by the EGFR/KRas signaling axis and miR-181d

PEAK1 is upregulated in multiple human malignancies and has been associated with tumor invasion and metastasis, but little is known about the role of PEAK1 in colorectal cancer (CRC) progression. We investigated the expression pattern, function and regulatory mechanisms of PEAK1 in CRC. Here, we found that PEAK1 is overexpressed in CRC tissues and that high PEAK1 expression...

Study of Electrical Conductivity and Microcosmic Structure of Tetrahedral Amorphous Carbon Films Doped by Boron

Received 10 September 2015; Revised 8 December 2015; Accepted 10 December 2015 Academic Editor: Antonio Riveiro Copyright © 2015 Xiaoyan Wang and Yuqing Zhao. This is an open access article distributed

Elevated tumor-to-liver uptake ratio (TLR) from 18F–FDG-PET/CT predicts poor prognosis in stage IIA colorectal cancer following curative resection

medical physicians (Dr. Zhanwen Zhang & Dr. Xiaoyan Wang) with more than 10 years of clinical experience in colorectal cancer imaging. The physicians identified visible lesions with high tracer uptake and

Involvement of aberrantly activated HOTAIR/EZH2/miR-193a feedback loop in progression of prostate cancer

Though androgen deprivation therapy is the standard treatment for prostate cancer (PCa), most patients would inevitably progress to castration-resistant prostate cancer (CRPC) which is the main cause of PCa death. Therefore, the identification of novel molecular mechanism regulating cancer progression and achievement of new insight into target therapy would be necessary for...

The effects of kisspeptin-10 on serum metabolism and myocardium in rats

Kisspeptin is a peptide encoded by the Kiss 1 gene and is also called metastin. Previous studies have generally focused on several functions of this peptide, including metastasis, puberty, vasoconstriction and reproduction. However, few studies have focused on the cardiac functions of kisspeptin. In the present study, cardiac histomorphology was observed via TEM (transmission...

Infliximab enhances the therapeutic effects of 5-fluorouracil resulting in tumor regression in colon cancer

Xiaoyan Wang 0 1 0 h unan Key Laboratory of Nonresolving Inflammation and Cancer , Changsha, Hunan , People's Republic of China 1 Department of Gastroenterology, The Third Xiangya Hospital of central south

Selection of the Inducer for the Differentiation of Chicken Embryonic Stem Cells into Male Germ Cells In Vitro

Several inducers have been used to differentiate embryonic stem cells (ESCs) into male germ cells but the induction process has been inefficient. To solve the problem of low efficiency of inducer for ESCs differentiation into male germ cells, all-trans retinoic acid (ATRA), Am80(the retinoic acid receptor agonist), and estradiol (E2) was used to induce ESCs to differentiate into...

Mesalazine-induced eosinophilic pneumonia with bone marrow infiltration: a case report and literature review

Mesalazine-induced eosinophilic pneumonia with bone marrow infiltration: a case report and literature review Yunjian Zhang,1 Ling Luo,1 Xiaofang Wang,1 Xiaoyang Liu,1 Xiaoyan Wang,1 Yi Ding2

Metabonomics Approach to Assessing the Modulatory Effects of Kisspeptin-10 on Liver Injury Induced by Heat Stress in Rats

) and the Fundamental research funds for the central Universities(KYZ201526). Author information Author notes Yuanlong Hou, Xiaoyan Wang and Jihui Ping contributed equally to this work ... Search for Xiaoyan Wang in:Nature Research journals • PubMed • Google Scholar Search for Jihui Ping in:Nature Research journals • PubMed • Google Scholar Search for Zhihai Lei in:Nature Research journals

Inhibition of HIV Virus by Neutralizing Vhh Attached to Dual Functional Liposomes Encapsulating Dapivirine

Although highly active antiretroviral therapy (HAART) has greatly improved the life expectancy of HIV/AIDS patients, the treatment is not curative. It is a global challenge which fosters an urgent need to develop an effective drug or neutralizing antibody delivery approach for the prevention and treatment of this disease. Due to the low density of envelope spikes with restricted...