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Can such an animal model truly represent Henoch–Schönlein purpura?

, Children's Hospital of Soochow University , Jingde Street 303, Suzhou 215000, Jiangsu , China 1 Xiaozhong Li 2 Department of Pediatrics, Affiliated Taixing Hospital of Yangzhou University , Taixing, Jiangsu

Petri net methodology for solving healthcare management issues

Various approaches of Petri nets can be achieved as system security and information flow in the healthcare recording system inside any medical or health-related business. Petri net system formal modeling is essential as well as important to track down the records and secure information inside a preformed health organization. In this paper, we mainly focused on the formal model...

GnRH Antagonist Improves Pubertal Cyclophosphamide-Induced Long-Term Testicular Injury in Adult Rats

Correspondence should be addressed to Xiaozhong Li; ten.haey@ncilgnohzoaix Received 16 January 2018; Revised 23 March 2018; Accepted 11 April 2018; Published 10 June 2018 Academic Editor: Małgorzata Kotula-Balak

GnRH Antagonist Improves Pubertal Cyclophosphamide-Induced Long-Term Testicular Injury in Adult Rats

Background. Gonadal injury following chemotherapy is of increasing importance with the continuous improvement of survival rates. The protection of gonadotropin hormone antagonist (GnRHant) in long-term adult survivors of adolescent cancers and some autoimmune diseases has not yet been evaluated. Methods. The present study was aimed at longitudinally exploring whether the GnRHant...

Children with Henoch–Schönlein purpura with low complement levels: follow-up for >6 years

, People's Republic of China 215003 1 Xiaozhong Li - Dear Editor In 2012, we published a study in Pediatric Nephrology in which we reported our findings that the reduction of complement in children with

Reliability Analysis of Random Fuzzy Unrepairable Systems

The lifetimes of components in unrepairable systems are considered as random fuzzy variables since randomness and fuzziness are often merged with each other. Then we establish the fundamental mathematical models of random fuzzy unrepairable systems, including series systems, parallel systems, series-parallel systems, parallel-series systems, and cold standby systems with...

Reliability Analysis of Random Fuzzy Unrepairable Systems

The lifetimes of components in unrepairable systems are considered as random fuzzy variables since randomness and fuzziness are often merged with each other. Then we establish the fundamental mathematical models of random fuzzy unrepairable systems, including series systems, parallel systems, series-parallel systems, parallel-series systems, and cold standby systems with...

Early urinary angiotensinogen excretion in critically ill neonates

Introduction: Urinary angiotensinogen is considered a reliable biomarker for intrarenal renin–angiotensin system activity. The aims of this study were to assess the urinary angiotensinogen level during the first day of life and to evaluate its correlation with renal function in critically ill neonates.

Association of Fluid Accumulation with Clinical Outcomes in Critically Ill Children with Severe Sepsis

Objective To evaluate whether early and acquired daily fluid overload (FO), as well as fluctuations in fluid accumulation, were associated with adverse outcomes in critically ill children with severe sepsis. Methods This study enrolled 202 children in a pediatric intensive care unit (PICU) with severe sepsis. Early fluid overload was defined as ≥5% fluid accumulation occurring in...

U-shaped relationship between early blood glucose and mortality in critically ill children

Background The aims of this study are to evaluate the relationship between early blood glucose concentrations and mortality and to define a ‘safe range’ of blood glucose concentrations during the first 24 h after pediatric intensive care unit (PICU) admission with the lowest risk of mortality. We further determine whether associations exist between PICU mortality and early...

Forecasting New Product Diffusion Using Grey Time-Delayed Verhulst Model

Taking account of the time-delayed phenomenon in diffusion of new products, we propose the time-delayed Verhulst model and then establish a grey time-delayed Verhulst model using the method of grey differential equations. The related parameter packets of this novel model are obtained under the rule of ordinary least squares (OLS). The results show that the traditional grey...

Forecasting New Product Diffusion Using Grey Time-Delayed Verhulst Model

Taking account of the time-delayed phenomenon in diffusion of new products, we propose the time-delayed Verhulst model and then establish a grey time-delayed Verhulst model using the method of grey differential equations. The related parameter packets of this novel model are obtained under the rule of ordinary least squares (OLS). The results show that the traditional grey...

Forecasting New Product Diffusion Using Grey Time-Delayed Verhulst Model

Li 0 Jong Hae Kim 0 School of Business, Jiangnan University , Wuxi 214122 , China Taking account of the time-delayed phenomenon in diffusion of new products, we propose the time-delayed Verhulst model

Forecasting New Product Diffusion Using Grey Time-Delayed Verhulst Model

Taking account of the time-delayed phenomenon in diffusion of new products, we propose the time-delayed Verhulst model and then establish a grey time-delayed Verhulst model using the method of grey differential equations. The related parameter packets of this novel model are obtained under the rule of ordinary least squares (OLS). The results show that the traditional grey...

Forecasting New Product Diffusion Using Grey Time-Delayed Verhulst Model

Taking account of the time-delayed phenomenon in diffusion of new products, we propose the time-delayed Verhulst model and then establish a grey time-delayed Verhulst model using the method of grey differential equations. The related parameter packets of this novel model are obtained under the rule of ordinary least squares (OLS). The results show that the traditional grey...

Long Non-Coding RNA Expression Profile in the Kidneys of Male, Low Birth Weight Rats Exposed to Maternal Protein Restriction at Postnatal Day 1 and Day 10

Background Long non-coding RNAs (lncRNAs), which are involved in a variety of biological functions and aberrantly expressed in many types of diseases, are required for postnatal development. In this study, we aimed to investigate the lncRNA profiles in low birth weight (LBW) rats with reduced nephron endowment induced by the restriction of maternal protein intake. LBW by reduced...

Addition of SNAP to perinatal risk factors improves the prediction of bronchopulmonary dysplasia or death in critically ill preterm infants

the membranes; RDS: Respiratory distress syndrome; ROC: Receiver operating characteristic; SNAP: The score for neonatal acute physiology; SNAP-II: SNAP version II. Authors information Xiaozhong Li and

Addition of SNAP to perinatal risk factors improves the prediction of bronchopulmonary dysplasia or death in critically ill preterm infants

death in neonates. Author’s information Xiaozhong Li and Xing Feng share corresponding authorship. Abbreviations AUC:  Area under the receiver-operating-characteristic curve BPD

Urinary protein markers predict the severity of renal histological lesions in children with mesangial proliferative glomerulonephritis

BackgroundSeveral renal histopathological features, including mesangial hypercellularity, glomerulosclerosis, tubular atrophy and interstitial fibrosis, are considered to be independent predictors of end-stage renal failure in patients with glomerular diseases. Mesangial proliferative glomerulonephritis (MesPGN) is characterized by proliferations of mesangial cells with increase...