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A Jacobi-Collocation Method for Second Kind Volterra Integral Equations with a Smooth Kernel

SCY1308. Haotao Cai is supported by Natural Science Foundation of Shandong Province Grant ZR2010AQ001. Xin Zhang is supported by Natural Science Foundation of Shandong Province Grant ZR2010AQ012

Control Allocation Design of Reaction Control System for Reusable Launch Vehicle

January 2014; Revised 13 April 2014; Accepted 13 April 2014; Published 12 June 2014 Academic Editor: Hui Zhang Copyright © 2014 Rongjun Mu and Xin Zhang. This is an open access article distributed under

Delivery of acetylthevetin B, an antitumor cardiac glycoside, using polymeric micelles for enhanced therapeutic efficacy against lung cancer cells

authors would like to thank Dr Zhuang WEI for generously providing lung carcinoma A549 cells. Author contribution Jing-jing ZHU performed most of the experiments and drafted the manuscript. Xin-xin ZHANG ... assisted in the extraction, isolation and characterization of ATB. Xin-xin ZHANG, Jin-shan TANG, and Yong GAN designed and directed the study and participated in the overall editing and approval of the paper

The PPARγ agonist, rosiglitazone, attenuates airway inflammation and remodeling via heme oxygenase-1 in murine model of asthma

, Yuan LIU, Yun LIU, and Man-xiang LI contributed to the research design; Jing XU performed the experiments and the data analysis with the assistance of Guizuo WANG, Yan-ting ZHU, Dong HAN, De-xin ZHANG

FoxM1 mediated resistance to gefitinib in non-smallcell lung cancer cells

. Acknowledgements This work was supported by the Shanghai Leading Academic Discipline Project( No B115) and China National ?985? Project (phase III). Author contribution Nuo XU and Xin ZHANG performed the research

Novel vehicle based on cubosomes for ophthalmic delivery of flurbiprofen with low irritancy and high bioavailability

-xin Zhang, Chun-liu Zhu & Li GanSchool of Pharmacy, China Pharmaceutical University, Nanjing 210009, ChinaJin-qiu ShenWuhan Wuyao Science & Technology Co Ltd, Wuhan 430033, ChinaHai-ming Geng ... • PubMed • Google ScholarSearch for Hai-ming Geng in:Nature Research journals • PubMed • Google ScholarSearch for Xin-xin Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Chun-liu Zhu

Effects of breast cancer resistance protein inhibitors and pharmaceutical excipients on decreasing gastrointestinal toxicity of camptothecin analogs

gastrointestinal toxicity of CPT. Author contribution Yong GAN, Xin-xin ZHANG, and Wei-san PAN designed the research; Xin-xin ZHANG and Li GAN carried out the research; Yong GAN and Wei-san PAN contributed ... materials and analytical tools; Chun-liu ZHU analyzed the data; Xin-xin ZHANG and Yong GAN wrote the paper. 1 Jaxel C , Kohn KW , Wani MC , Wall ME , Pommier Y . Structureactivity study of the actions of

Study on Bottom Damp-Proof Method of Cave Dwelling

The cave dwelling, as one of the most typical and traditional characteristic local housing styles in the loess area of Northwest China, has been adopted widely in many areas since ancient times. The construction of the cave dwellings supports environmental protection, makes use of innovative construction technology, and preserves historical cultural heritage. The cave dwellings...

Static and Dynamic Load Tests of Shaft and Base Grouted Concrete Piles

This paper examines shaft and base grouted concrete piles by conducting vertical static load tests (SLTs) and dynamic load tests. Three concrete piles with shaft and base grouting, with base grouting only, and without grouting techniques were selected, and compressive SLTs were conducted. Two piles with grouting were also assessed with dynamic load tests. Another two uplift SLTs...

Mixing in the Minimal Flavor-Violating Two-Higgs-Doublet Models

The work is supported by the National Natural Science Foundation of China (NSFC) under Contract nos. 11675061 and 11435003. Xin Zhang is supported by the CCNU-QLPL Innovation Fund (QLPL2015P01

Analysis and simulation of high-power LED array with microchannel heat sink

The high power light emitting diode (LED) array integrated with the microchannel heat sink is designed in this paper, and then optimal analysis and simulation have been carried out. According to the theory of heat transfer and fluid mechanics, the calculation of the thermal resistance for the microchannel heat sink is obtained, and the thermal resistance is minimized. Finally the...

Numerical Simulation of Rock Plate Cutting with Three Sides Fixed and One Side Free

In order to overcome conical pick wear in the traditional rock cutting method, a new cutting method was proposed on account of increasing free surface of the rock. The mechanical model of rock plate bending under concentrated force was established, and the first fracture position was given. The comparison between experimental and numerical results indicated that the numerical...

Numerical Simulation of Fragment Separation during Rock Cutting Using a 3D Dynamic Finite Element Analysis Code

To predict fragment separation during rock cutting, previous studies on rock cutting interactions using simulation approaches, experimental tests, and theoretical methods were considered in detail. This study used the numerical code LS-DYNA (3D) to numerically simulate fragment separation. In the simulations, a damage material model and erosion criteria were used for the base...

Characterization and Alumina Leachability of 12CaO·7Al2O3 with Different Holding Times

The effect of synthesis time on phase compositions, lattice constant, average grain size, preferred orientation, and surface morphology of 12CaO·7Al2O3 synthesized at 1500°C was analyzed by XRD and SEM. The results indicate that the main phase of samples synthesized is 12CaO·7Al2O3 when holding time is over 30 min. The lattice constant increases and the preferred orientation...

A vaccine with Aβ oligomer-specific mimotope attenuates cognitive deficits and brain pathologies in transgenic mice with Alzheimer’s disease

Background β-Amyloid peptide (Aβ) oligomers are initial factors used to induce Alzheimer’s disease (AD) development, and Aβ monomers have normal physiological function. The antibodies or vaccines against Aβ monomers have serious problems, such as side effects and low curative effects. Therefore, it is essential to specifically target Aβ oligomers rather than monomers for the...

Dietary Vitamin C Intake and Lung Function in Rural China

The relation between dietary vitamin C intake and pulmonary function was investigated in a cross-sectional study carried out in 69 counties in rural China in 1989. Within each of the 69 counties, 120 subjects aged 35–64 years were identified using a three-stage random clustering procedure. Each subject underwent pulmonary function testing, completed a detailed questionnaire, and...

Silencing of microRNA-101 prevents IL-1β-induced extracellular matrix degradation in chondrocytes

Introduction Extracellular matrix (ECM) degradation leads to malfunction of the cartilage in osteoarthritis (OA). Inflammatory cytokine interleukin-1 beta (IL-1β) functions in ECM degradation and prevents ECM synthesis by down-regulating the key transcription factor, Sox9, and consequently inhibiting ECM gene expression. Evidence reveals that microRNAs (miRNA) have been...

Evaluation of copy number variation detection for a SNP array platform

Background Copy Number Variations (CNVs) are usually inferred from Single Nucleotide Polymorphism (SNP) arrays by use of some software packages based on given algorithms. However, there is no clear understanding of the performance of these software packages; it is therefore difficult to select one or several software packages for CNV detection based on the SNP array platform.We...

The expression of beclin-1, an autophagic gene, in hepatocellular carcinoma associated with clinical pathological and prognostic significance

Background A role for autophagy, a conserved cellular response to stress, has recently been demonstrated in human cancers. Aberrant expression of Beclin-1, an important autophagic gene, has been reported in various human cancers. In the present study, we investigated the significance and relationship between Beclin-1 expression and cell proliferation, apoptosis, microvessel...